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References

Moringa

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  1. Rockwood JL, Anderson BG, Casamatta DA. Potential uses of Moringa oleifera and an examination of antibiotic efficacy conferred by M. oleifera seed and leaf extracts using crude extraction techniques available to underserved indigenous populations. Int J Phytothearpy Res. 2013;3(2):61–71.

  2. Oduro I, Ellis WO, Owusu D. Nutritional potential of two leafy vegetables: Moringa oleifera and Ipomoea batatasleaves. Sci Res Essays. 2008;3(2):57–60.

  3. Kasolo JN, Bimenya GS, Ojok L, et al. Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities. J Med Plants Res. 2010;4(9):753–757.

  4. Monik Adriaens. Family Medicinal Plant Gardens in the Rwenzori Region. Marianum Press Ltd. 2006; 79-82.

  5. Mutiara TK, Harijono, Teti Estiasih, et al. Effect lactagogue moringa leaves Moringa oleifera Lam powder in rats.J Basic Appl Sci Res. 2013;3(4):430–434.

  6. Thurber MD, Fahey JW. Adoption of Moringa oleifera to combat under-nutrition viewed through the lens of the diffusion of innovations theory. Ecol Food Nutr. 2010;48(3):212–225.

  7. Mbikay M. Therapeutic potential of Moringa oleifera leaves in chronic hyperglycemia and dyslipidemia: a review. Front Pharmacol. 2012;3:24.

  8. Berkovich L, Earon G, Ron I, et al. Moringa oleifera aqueous leaf extract down-regulates nuclear factor-kappaB and increases cytotoxic effect of chemotherapy in pancreatic cancer cells. BMC Complement Altern Med. 2013;13:212.

  9. Sánchez Machado DI, Núñez Gastélum JA. Reyes Moreno C, et al. Nutritional quality of edible parts of Moringa oleifera. Food Anal Methods. 2010;3(3):175–180.

  10. Barminas JT, Charles M, Emmanuel D. Mineral composition of non-conventional leafy vegetables. Plant Foods Hum. Nutr.1998;53(1):29–36.

  11. Olagbemide PT, Alikwe PC. Proximate analysis and chemical composition of raw and defatted Moringa oleifera kernel. Adv Life Sci Technol. 2014;24:92–99.

  12. Moringa Leaf Powder: A nutritional analysis of leaf powder.

  13. Ijarotimi OS, Adeoti O, Ariyo O. Comparative study on nutrient composition, phytochemical, and functional characteristics of raw, germinated, and fermented Moringa oleifera seed flour.Food Sci Nutr. 2013;1(6):452–463.          

  14. Mishra SP, Singh P, Singh S. Processing of Moringa oleifera leaves for human consumption. Bull Environ Pharmacol Life Sci. 2012;2(1):28–31.

  15. Sallau B, Mada SB, Ibrahim S. Effect of boiling, simmering and blanching on the antinutritional content of Moringa oleifera leaves. Int J Food Nutr Saf. 2012;2:1–6.

  16. Kachik F, Mudlagiri BG, Gary RB, et al. Effects of food preparation on qualitative and quantitative distribution of major carotenoids constituents of tomatoes and several green vegetables. J Agric Food Chem.1992;40(3):390–398.

  17. Yang R, Chang L, Hsu J, et al. Nutritional and functional properties of moringa leaves from germplasm, to plant, to food, to health. Am Chem Soc. 2006;1–17.

  18. Kiranawati TW, Nurjanah N. Improvement of noodles recipe for increasing breastmilk: design of the Moringa noodles. Am J Food Sci Technol. 2014;2(3):88–92.

  19. Asiedu Gyekye IJ, Frimpong Manso S, Awortwe C, et al. Micro and macroelemental composition and safety evaluation of the nutraceutical Moringa oleifera leaves. J Toxicol. 2014:1–13.

  20. Kaneto H, Kajimoto Y, Miyagawa J, et al. Beneficial effects of antioxidants in diabetes: possible protection of pancreatic β -cells against glucose toxicity. Diabetes. 1999;48(12):2398–2406.

  21. Prentki M, Nolan CJ. Islet β cell failure in type 2 diabetes. J Clin Invest. 2006;116(7):1802–1812.

  22. Kamalakkannan N, Prince PS. Antihyperglycaemic and antioxidant effect of rutin, a polyphenolic flavonoid, in streptozotocin-induced diabetic wistar rats. Basic Clin Pharmacol Toxicol. 2006;98(1):97–103.

  23. Al Malki AL, El Rabey HA. The antidiabetic effect of low doses of Moringa oleifera Lam. seeds on streptozotocin induced diabetes and diabetic nephropathy in male rats. Biomed Res Int. 2015:1–13.

  24. Aronson D, Rayfield RA. How hyperglycemia promotes atherosclerosis: molecular mechanisms. Cardiovasc Diabetol. 2002;1:1.

  25. Chumark P, Khunawat P, Sanvarinda Y, et al. The in vitro and ex vivo antioxidant properties, hypolipidaemic and antiatherosclerotic activities of water extract of Moringa oleifera Lam. Leaves. J Ethnopharmacol. 2008;116(3):439–446.

  26. Tiloke C, Phulukdaree A, Chuturgoon AA. The antiproliferative effect of Moringa oleifera crude aqueous leaf extract on cancerous human alveolar epithelial cells. BMC Complement Altern Med. 2013;13:226–233.

  27. Jung IL. Soluble extract from Moringa oleifera leaves with a new anticancer activity. PLoS ONE. 2014;9(4):1–10.

  28. Leelawat S, Leelawat L. Moringa olefiera extracts induce cholangiocarcinoma cell apoptosis by induction of reactive oxygen species production. Int J Pharmacogn Phytochem Res. 2014;6(2):183–189.

  29. Liou GY, Storz P. Reactive oxygen species in cancer. Free Radic Res. 2010;44(5):479–496.

  30. Hermawan, Nur KA, Sarmoko, et al. Ethanolic extract of Moringa oleifera increased cytotoxic effect of doxorubicin on HeLa cancer cells. J Nat Remedies. 2012;12(2):108–114.

  31. Fahey J, Muna Abdalla I. Moringa oleifera: a review of the medical evidence for its nutritional, therapeutic, and prophylactic properties. Trees Life J. 2005;1:1–33.

  32. Miyoshi N, Uchida K, Osawa T, et al. A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation. Cancer Res. 2004;64(6):2134–2142.

  33. Lee YJ, Shacter E. Oxidative stress inhibits apoptosis in human lymphoma cells. J Biol Chem. 1999;274(28):19792–19798.

  34. Baker K, Marcus CB, Huffman K, et al. Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury. J Pharmacol Exp Ther.1998;284(1):215–221.

  35. Kirisattayakul W, Wattanathorn J, Tong Un T, et al. Cerebroprotective effect of Moringa oleifera against focal ischemic stroke induced by middle cerebral artery occlusion. Oxid Med Cell Longev. 2013:10–13.

  36. Sutalangka C, Wattanathorn J, Muchimapura S, et al. Moringa oleifera mitigates memory impairment and neurodegeneration in animal model of age-related dementia. Oxid Med Cell Longev. 2013:1–9.

  37. Adeyemi OS, Elebiyo TC. Moringa oleifera supplemented diets prevented nickel-induced nephrotoxicity in Wistar rats. J Nutr Metab. 2014:1–8.

  38. Ravikumar K, Sheeja AK. Heavy metal removal from water using Moringa oleifera seed coagulant and double filtration. Int J Sci Eng Res. 2013;4(5):10–13.

  39. Mahajan GS, Mehta AA. Anti-arthritic activity of hydroalcoholic extract of flowers of Moringa oleifera lam. in Wistar rats. J Herbs Spices Med Plants. 2009;15(2):149–163.

  40. Chen M, Verdes RP. Elucidation of bactericidal effects incurred by Moringa oleifera and Chitosan. J US SJWP. 2009;4:65–79.

  41. Viera GHF, Mourão JA, Ângelo AM, et al. Antibacterial effect in vitro of Moringa oleifera and Annona muricata against Gram positive and Gram negative bacteria. Rev Ins Med Trop Sao Paulo. 2010;52(3):129–132.

  42. Jahn SA, Musnad HA, Burgstaller H. The tree that purifies water: cultivating multipurpose Moringaceae in the Sudan Unasylva. 1986;38:23–28.

  43. Choudhary MK, Bodakhe SH, Gupta SK. Assessment of the antiulcer potential of Moringa oleifera root-bark extract in rats. J Acupunct Meridian Stud. 2013;6(4):214–220.

  44. Nair S, Varalakshmi KN. Anticancer, cytotoxic potential of Moringa oleifera extracts on HeLa cell line. J Nat Pharm. 2011;2:138–142

  45. Monera TG, Maponga CC. Prevalence and patterns of Moringa oleifera use among HIV positive patients in Zimbabwe: a cross-sectional survey. J Public Health Afr. 2012;3(1):6–8.

  46. Lalas S, Tsaknis J. Characterization of Moringa oleifera seed oil variety Periyakulam-1. J Food Compos Anal. 2002;15(1):65–77.

  47. Lurling M, Beekman W. Anticyanobacterial activity of Moringa oleifera seeds. J Appl Phycol. 2010;22(4):503–510.

  48. Sengupta ME, Keraita B, Olsen A, et al. Use of Moringa oleifera seed extracts to reduce helminth egg numbers and turbidity in irrigation water. Water Res. 2012;46(11):3646–3656.

  49. Suhartini S, Hidayat N, Rosaliana E. Influence of powdered Moringa oleifera seeds and natural filter media on the characteristics of tapioca starch wastewater. Int J Recycl Org Waste Agric. 2013;2:1–11.

  50. Santos TR, Silva MF, Nishi L, et al. Development of a magnetic coagulant based on Moringa oleifera seed extract for water treatment. Environ Sci Pollut Res. 2016:23(8):7692–700.

  51. Adejumo OE, Kolapo AL, Folarin AO. Moringa oleifera Lam. Moringaceae grown in Nigeria: in vitro antisickling activity on deoxygenated erythrocyte cells. J Pharm Bioall Sci. 2012;4(2):118–122.

  52. Shank LP, Riyathong T, Lee VS, et al. Peroxidase activity in native and callus culture of Moringa oleifera Lam. J Med Bioeng. 2013;2(3):163–167.

  53. Fuglie LJ. The Moringa Tree: A local solution to malnutrition; Church World Service in Senegal: 2005

  54. Aluko O, Brai MR, Adelore AO. Materials evaluation of sensory attributes of snack from maize-moringa seed flour blends. Int J Innov Res Sci Eng Technol. 2013;7:597–599.

  55. Owusu D, Oduro I. Development of crackers from cassava and sweetpotato flours using Moringa oleiferaand Ipomoea batatas leaves as fortificant. Am J Food Nutr. 2011;1(3):114–122.

  56. Raphaël KJ. Effects of substituting soybean with Moringa oleifera meal in diets on laying and eggs quality characteristics of KABIR chickens. J Anim Nutr. 2015;1(4):1–6.

  57. Olugbemi TS, Mutayoba SK, Lekule FP. Effect of Moringa M. oleifera inclusion in cassava based diets fed to broiler chickens. Int J Poult Sci. 2010;9(4):363–367.

  58. Zeng B, Luo J, Wang P, et al. The beneficial effects of Moringa oleifera leaf on reproductive performance in mice. Food Sci Nutr. 2019;7(2):738-746. Published 2019 Jan 22. doi:10.1002/fsn3.918

Spirulina

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1. Amha Belay, Yoshimichi Ota (1993): Current knowledge on potential health benefits of Spirulina. Pub. in Journal of Appl. Phycology, 5:235-241.

2. Ayehunie S, Belay A, Baba TW, et al. (1998): Inhibition of HIV-1 replication by an aqueous extract of Spirulina platensis (Arthrospira platensis). J Acquir Immune Defic Syndr Hum Retrovirol, 18:7"“12.

3. Becker EW, Jakober B, Luft D, et al.(1986): Clinical and biochemical evaluations of the alga Spirulina with regard to its application in the treatment of obesity. A double-blind crossover study. Nutr Rep Intl, 33:565"“73.

4. Bioavailability of spirulina carotenes in preschool children. by V. Annapurna, et al. 1991. National Institute of Nutrition, Hyderabad, India. J. Clin. Biochem Nutrition. 10 145-151. India.

5. Large scale nutritional supplementation with spirulina alga. by C.V. Seshadri. 1993. All India Coordinated Project on Spirulina. Shri Amm Murugappa Chettiar Research Center (MCRC) Madras, India.

6. Prevention of experimental oral cancer by extracts of spirulina-dunaliella algae. by J. Schwartz, G. Shklar, et al. 1988. Harvard School of Dental Medicine. Pub. in Nutrition and Cancer, 11, 127-134. 1988. USA.

7. Clinical and biochemical evaluations of spirulina with regard to its application in the treatment of obesity. by E.W. Becker, et al. 1986. Inst. Chem. Pfanz. Pub. in Nutrition Reports Int'l, Vol. 33, No. 4, pg 565. Germany.

8. Effects of spirulina on hypercholesterolemia and fatty liver in rats. by T. Kato and K. Takemoto. 1984. Saitama Medical College. Pub. in Japan Nutr. Foods Assoc. Journal. 37:323. Japan.

9. Dagnelie PC, van Staveren WA, van den Berg H. (1991): Vitamin B-12 from algae appears not to be bioavailable. Am J Clin Nutr, 53:695"“97.

10. Qureshi M.A., Kidd M.T., and Ali R.A., Journal of Nutritional Immunology V.3(4) 1995, pages 35-45. Spirulina platensis Extract Enhances Chicken Macrophage Functions After in vitro Exposure.

11. Dillon JC, Phuc AP, Dubacq JP. (1995): Nutritional value of the alga Spirulina. World Rev Nutr Diet, 77:32"“46.

12. Gonzalez de Rivera C, Miranda-Zamora? R, Diaz-Zagoya? JC, et al. (1993): Preventive effect of Spirulina maxima on the fatty liver induced by a fructose-rich diet in the rat, a preliminary report. Life Sci, 53:57"“6

13. Inhibition of HIV-1 replication by an aqueous extract of spirulina. by Ayehunie, Belay et al. 7th IAAA Conf., Knysna, South Africa. 1996. USA.

14. Calcium Spirulan, an inhibitor of enveloped virus replication, from a blue-green alga Spirulina. by Hayashi et al. 1996. Pub. in Journal of Natural Products, 59, 83-87. Japan.

15. Antiviral activity of blue-green algae cultures. by Patterson. Pub. in Journal of Phycology 29, 125-130. USA.

16. AIDS Antiviral sulfolipids from cyanobacteria (blue-green algae). by K. Gustafson, et al. 1989. Pub. in Journal of the National Cancer Institute, August 16, 1989, pg 1254. USA.

17. Evaluation of chemoprevention of oral cancer with spirulina. by Babu, M. et al. 1995. Pub. in Nutrition and Cancer, Vol. 24, No. 2, 197-202. India.

18. Inhibitive effect and mechanism of polysaccharide of spirulina on transplanted tumor cells in mice. by Lisheng, et al. 1991. Pub. in Marine Sciences, Qingdao, N.5. pp 33-38. China.

19. Enhancement of endonuclease activity and repair DNA synthesis by polysaccharide of spirulina. by Qishen, P. et al. 1988. Pub. in Chinese Genetics Journal, 15 (5) 374-381. China.

20. Inhibition of experimental oral carcinogenesis by topical beta carotene. by Schwartz, et al. 1986. Harvard School of Dental Medicine. Pub. in Carcinogenesis, May 1986 7(5) 711-715. USA.

21. Hayashi K, Hayashi T, Kojima I. (1996): A natural sulfated polysaccharide, calcium spirulan, isolated from Spirulina platensis: in vitro and ex vivo evaluation of anti-herpes simplex virus and anti-human immunodeficiency virus activities. AIDS Res Hum Retroviruses, 12:1463"“71.

22. Inhibition of experimental oral carcinogenesis by topical beta carotene. by Schwartz, et al. 1986. Harvard School of Dental Medicine. Pub. in Carcinogenesis, May 1986 7(5) 711-715. USA.

23. Hayashi O, Katoh T, Okuwaki Y. (1994): Enhancement of antibody production in mice by dietary Spirulina platensis. J Nutr Sci Vitaminol (Tokyo), 40:431"“41.

24. Hongyan Wu, Kunshan Gao, Virginia E. Villafañe, Teruo Watanabe, E. Walter Helbling (2005): Effects of Solar UV Radiation on Morphology and Photosynthesis of Filamentous Cyanobacterium Arthrospira (Spirulina) platensis. Applied and Environmental Microbiology, 71(9): 5004-5013.

25. Iwata K, Inayama T, Kato T. (1990): Effects of Spirulina platensis on plasma lipoprotein lipase activity in fructose-induced hyperlipidemic rats. J Nutr Sci Vitaminol (Tokyo), 36:165"“71.

26. Johnson PE, Shubert LE. (1986): Accumulation of mercury and other elements by spirulina (cyanophyceae). Nutr Rep Intl, 34(6):1063"“71.

27. Kapoor R, Mehta U. (1993): Effect of supplementation of blue green alga (Spirulina) on outcome of pregnancy in rats. Plant Foods Hum Nutr 1993; 43:29"“35.

28. Kebede Elizabeth (1996): Phytoplankton in a Salinity-Alkalinity? Series of Lakes in the Ethiopian Rift Valley. Uppsala University (Sweden), 178 pp.

29. Kim HM, Lee EH, Cho HH, et al. (1998): Inhibitory effect of mast cell-mediated immediate-type allergic reactions in rats by spirulina. Biochem Pharmacol, 55:1071"“76.

30. Mathew B, Sankaranarayanan R, Nair PP, et al. (1995): Evaluation of chemoprevention of oral cancer with Spirulina fusiformis. Nutr Cancer, 24:197"“202.

31. Mishima T, Murata J, Toyoshima M, et al. (1998): Inhibition of tumor invasion and metastasis by calcium spirulan (Ca-SP), a novel sulfated polysaccharide derived from a blue-green alga, Spirulina platensis. Clin Exp Metastasis, 16:541"“50.

32. Nakashima MJ, Angold S, Beavin BB, et al. (1989): Extraction of light filth from Spirulina powders and tablets: collaborative study. J Assoc Off Anal Chem, 72:451"“53.

33. Nakaya N, Homma Y, Goto Y. (1988): Cholesterol lowering effect of Spirulina. Nutr Rep Intl 1988; 37:1329"“37.

34. Microalga Spirulina. by Robert Henrikson. 1993. Pub. by Ediciones Urano, Barcelona Spain (in Spanish). Oikos Pharmaceuticals, C/ San Pedro, 29640 Fuengirola, Málaga, Costa del Sol, España.

35. Orio Ciferri (1983): Spirulina, the edible organism. Microbiological Reviews, 47(4): 551"“578.

36. Schwartz J, Shklar G, Reid S, Trickler D. (1988): Prevention of experimental oral cancer by extracts of Spirulina-Dunaliella? algae. Nutr Cancer, 11:127"“34.

37. Susan M. Aubrey (2006): Spirulina: Answer for the hungry. Family Health News, www.familyhealthnews.com/articles-spirulina.html

38. Yang HN, Lee EH, Kim HM. (1997): Spirulina inhibits anaphylactic reaction. Life Sci, 61:1237"“44.

39. Hayashi K., et al, Phytotherapy Research, Vol. 7, 76-80 (1993). An Extract from Spirulina platensis is a Selective Inhibitor of Herpes Simplex Virus Type 1 Penetration into HeLa Cells.

40. Remirez, D., R. Gonzalez, N. Merino, et al. "Inhibitory Effects of Spirulina in Zymosan-Induced Arthritis in Mice." Mediators of Inflammation 11 (April 2002): 75-79.

41. Remirez, D., N. Ledon, and R. Gonzalez. "Role of Histamine in the Inhibitory Effects of Phycocyanin in Experimental Models of Allergic Inflammatory Response." Mediators of Inflammation 11 (April 2002): 81-85.

42. Tonnina, D., et al. "Integral Toxicity Test of Sea Waters by an Algal Biosensor." Annali di Chimica (Rome) 92 (April 2002): 477-484.

43. Varga, L., J. Szigeti, R. Kovacs, et al. "Influence of a Spirulina platensis Biomass on the Microflora of Fermented ABT Milks During Storage (R1)." Journal of Dairy Science 85 (May 2002): 1031-1038.

44. EarthNet. EarthNet Scientific Health Library. http://www.spirulina.com/SPLAbstracts1.html (2000). Earthrise. Spirulina Library Abstracts and Summaries.

45. http://www.earthrise.com/ERLibAbstracts2.html (2000). Mayo Clinic. Mayo Clinic: Blue-green algae. http://www.mayohealth.org/mayo/askdiet/htm/new/qd970618.htm (1997).

46. Chen LL et al. [Experimental study of spirulina platensis in treating allergic rhinitis in rats]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2005 Feb;30(1):96-8.

47. Radioprotective effect of extract from spirulina in mouse bone marrow cells studied by using the micronucleus test. by P. Qishen, Kolman et al. 1989. In Toxicology Letters 48: 165-169. China.

48. Enhancement of endonuclease activity and repair DNA synthesis by polysaccharide of spirulina. by Qishen, P. et al. 1988. Pub. in Chinese Genetics Journal, 15 (5) 374-381. China.

49. Means to normalize the levels of immunoglobulin E, using the food supplement Spirulina. by L. Evets, et al. 1994. Grodenski State Medical Univ. Russian Federation Committee of Patents and Trade. Patent (19)RU (11)2005486. Jan. 15, 1994. Russia.

50. Radioprotective effect of extract from spirulina in mouse bone marrow cells studied by using the micronucleus test. by P. Qishen, Kolman et al. 1989. In Toxicology Letters 48: 165-169. China.

51. Spirulina- natural sorbent of radionucleides. by L.P. Loseva and I.V. Dardynskaya. Sep 1993. Research Institute of Radiation Medicine, Minsk, Belarus. 6th Int'l Congress of Applied Algology, Czech Republic. Belarus.

52. Observations on the utilization of spirulina as an adjuvant nutritive factor in treating some diseases accompanied by a nutritional deficiency. by V. Fica, et al. 1984. Clinica II Medicala, Spitalui Clinic, Bucuresti. Med. Interna 36 (3). Romania. (In Romanian).

53. Means to normalize the levels of immunoglobulin E, using the food supplement Spirulina. by L. Evets, et al. 1994. Grodenski State Medical Univ. Russian Federation Committee of Patents and Trade. Patent (19)RU (11)2005486. Jan. 15, 1994. Russia.

54. Cingi C et al. The effects of spirulina on allergic rhinitis. Eur Arch Otorhinolaryngol. 2008 Oct;265(10):1219-23. Epub 2008 Mar 15.

55. Mao TK et al. Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. J Med Food. 2005 Spring;8(1):27-30.

56. Mathew B, Sankaranarayanan R, Nair PP, et al. Nutr Cancer. 1995; 24(2):197-202.

57. Large scale nutritional supplementation with spirulina alga. by C.V. Seshadri. 1993. All India Coordinated Project on Spirulina. Shri Amm Murugappa Chettiar Research Center (MCRC) Madras, India.

58. Marles RJ et al. United States pharmacopeia safety evaluation of spirulina. Crit Rev Food Sci Nutr. 2011 Aug;51(7):593-604.

59. Kapoor R, Mehta U. 34_ 1993 Jul;44(1):2934. Iron status and growth of rats fed different dietary iron sources.

60. Ayehunie S., Belay A., Hu Y., Baba T., Ruprecht R., 7th IAAA Conference, Knysna, South Africa April 17, 1996. Inhibition of HIV-1 replication by an aqueous extract of Spirulina platensis (Arthrospira platensis).

61. Baojiang G., et al, Second Asia-Pacific Conference on Algal Biotechnology, April 25-27, 1994, p. 24. Study on Effect and Mechanism of Polysaccharides of Spirulina platensis on Body Immune Functions Improvement.

62. Babu.,M., et al, Nutrition and Cancer 1995, V. 24, No. 2, p.197-202. Evaluation of Chemoprevention of Oral Cancer with Spirulina fusiformis.

63. Belay A., Ota Y., Miyakawa K., Shimamatsu H., Journal of Applied Phycology 5:235-241, 1993. Current Knowledge on Potential Health Benefits of Spirulina.

64. Carmichael, et al Scientific American January 1995. "The Toxins of Cyanobacteria."

65. Evets L.B. et al Grodenski State Medical University, January 15, 1994 Russian Federation Committee of Patents and Trade, Patent Number: (19) RU (11) 2005486 C1 (51) 5 A 61K35/80. Means to Normalize the levels of Immunoglobulin E Using the Food Supplement Spirulina.

66. Fukino H., Takagi Y., Yamane Y., Eisei Kagaku 36: 5.,1990. Effect of Spirulina Platensis on the renal toxicity induced by inorganic mercury and cisplatin.

67. Hayashi O., et al, Journal of Nutritional Sciences and Vitaminology, 40, 431-441, 1994. Enhancement of Antibody Production in Mice by Dietary Spirulina platensis.

68. Hypocholesterolemic effect of blue-green algae spirulina spirulina in albino rats. by M.A. Devi and L.V. Venkataraman. 1983. Pub. in Nutrition Reports Int'l, 28:519-530. India.

69. The effect of spirulina on reduction of serum cholesterol. by N. Nayaka, et al. 1986. Tokai Univ. Pub. in Progress in Medicine, Vol. 36, No. 11. Japan.

70. Effect of water soluble and water insoluble fractions of spirulina over serum lipids and glucose resistance of rats. by Y. Takai, et al. 1991. Pub. in J. Japan Soc. Nutr. Food Science, 44:273-277. Japan.

71. Effects of spirulina on plasma lipoprotein lipase activity in rats. by K. Iwata, et al. 1990. Pub. .in Journal Nutr. Sci. Vitaminol, 36:165-171. Japan.

72. Current knowledge on potential health benefits of spirulina. by Amha Belay and Yoshimichi Ota. 1993. Pub. in Journal of Appl. Phycology, 5:235-241. USA.

73. Health Benefits of Spirulina. by Denise Fox. 1993. In Spirulina, Algae of Life. April 1993. Bulletin No. 12. Pub. by Institute Oceanographique, Monaco.

74. Microalgae as Food and Supplement by Robert A. Kay. 1991. In Critical Reviews in Food Science and Nutr. 30(6):555-573. Pub. by CRC Press. USA.

75. Spirulina: a model for microalgae as human food. by Alan Jassby. 1988. In Algae and Human Affairs. edited by Lembi and Waaland. Pub. by Cambridge Univ. Press, Cambridge, UK.

76. Spirulina, the edible organism. by Orio Ciferri. 1983. In Microbiological Reviews.Dec 1983. 551-578. Italy.

77. Kolman A., et al Toxicology Letters, 48 (1989) 165-169 Elsevier. Radioprotective effect of extract from Spirulina platensis in mouse bone marrow cells studied by using the micronucleus test.

78. Lisheng L., et al, Marine Sciences, Qindao China, N. 5, 1991, p. 33-38. Inhibitive Effective and Mechanism of Polysaccharide of Spirulina platensis on Transplanted Tumor Cells in Mice.

79. Pang Qishen et al, Acta Genetica Sinica (Chinese Journal of Genetics), V.15(5) p. 374-381, 1988. Enhancement of Endonuclease Activity and repair DNA Synthesis by Polysaccharide of Spirulina platensis.

80. Qureshi M.A., Garlich J.D., Kidd M.T., Immunopharmacology and Immunotoxicology, 1996 (submitted), "Dietary Spirulina platensis Enhances Humoral and Cell-mediated Immune Functions In Chickens".

81. Zhang C., et al, 1994 Second Asia-Pacific Conference on Alga Biotechnology, April 25-27, p.58. The Effects of Polysaccharide and Phycocyanin from Spirulina platensis variety on Peripheral blood and Hematopoietic system of Bone Marrow in Mice.

82. Vonshak, A. (ed.). Spirulina platensis (Arthrospira): Physiology, Cell-biology and Biotechnology. London: Taylor & Francis, 1997.

83. Spirulina. A Good Health Guide. by Jack Joseph Challem. 1981. Pub. by Keats Publishing, New Canaan, CT. USA.

84. Ciferri O (December 1983). "Spirulina, the edible microorganism". Microbiol. Rev. 47 (4): 551"“78. PMC 283708. PMID 6420655.

85. Habib, M. Ahsan B.; Parvin, Mashuda; Huntington, Tim C.; Hasan, Mohammad R. (2008). "A Review on Culture, Production and Use of Spirulina as Food dor Humans and Feeds for Domestic Animals and Fish". Food and Agriculture Organization of The United Nations. Retrieved November 20, 2011.

86. Effects of polysaccharide and phycocyanin from spirulina on peripheral blood and hematopoietic system of bone marrow in mice. by Zhang Cheng-Wu, et al.. April 1994. Nanjing Univ. China. Pub. in Proc. of Second Asia Pacific Conf. on Algal Biotech. Univ. of Malaysia. p.58. China.

87. Enhancement of antibody production in mice by dietary spirulina. by Hayashi, et al. June 1994. Kagawa Nutrition Univ. Japan. Pub. in Journal of Nutr. Science and Vitaminology. Japan.

88. Immune enhancement potential of spirulina in chickens. by M. Quereshi, et al. August 1994. Poultry Science Assoc. Dept. of Poultry Science, North Carolina State, NC. Pub. in Journal of Poultry Science Vol 73, S.1. p. 46. USA.

89. Immunomodulary effects of spirulina supplementation in chickens. by M. Qureshi, et al. May 1995. North Carolina State. Pub. in Proc. of 44th Western Poultry Disease Conference, pp 117-120. USA.

90. Immunostimulating activity of lipopolysaccharides from blue-green algae. by L. Besednova, et al. 1979. Pub. in Zhurnal Mikrobiologii, Epidemiologii, Immunobiologii, 56(12) pp 75-79. Russia.

91. Inhibitive effect and mechanism of polysaccharide of spirulina on transplanted tumor cells in mice. by Lisheng, et al. 1991.Pub. in Marine Sciences, Qingdao, N.5. pp 33-38. China.

92. Abdulqader, G., Barsanti, L., Tredici, M. "Harvest of Arthrospira platensis from Lake Kossorom (Chad) and its household usage among the Kanembu." Journal of Applied Phycology. 12: 493-498. 2000.

93. Babadzhanov A.S. et al.. "Chemical Composition of Spirulina Platensis Cultivated in Uzbekistan". Chemistry of Natural Compounds 40 (3): 2004.

94. "Blue-green algae". MedlinePlus. U.S. National Library of Medicine. November 18, 2010. Retrieved April 15, 2011.

95. a b Watanabe F (2007). "Vitamin B12 sources and bioavailability.". Exp. Biol. Med. (Maywood) 232 (10): 1266"“74. doi:10.3181/0703-MR-67. PMID 17959839. "Most of the edible blue-green algae (cyanobacteria) used for human supplements predominantly contain pseudovitamin B(12), which is inactive in humans. The edible cyanobacteria are not suitable for use as vitamin B(12) sources, especially in vegans."

96. Watanabe F, Katsura H, Takenaka S, Fujita T, Abe K, Tamura Y, Nakatsuka T, Nakano Y (1999). "Pseudovitamin B(12) is the predominant cobamide of an algal health food, spirulina tablets.". J. Agric. Food Chem. 47 (11): 4736"“41. doi:10.1021/jf990541b. PMID 10552882. "The results presented here strongly suggest that spirulina tablet algal health food is not suitable for use as a B12 source, especially in vegetarians."

97. Qureshi M.A., Ali R.A., Immunopharmacology, Jan. 1996. Phagocytic potential of Feline macrophages after exposure to a water soluble extract of spirulina in vitro.

98. a b c Tokusoglu O., Unal M.K. "Biomass Nutrient Profiles of Three Microalgae: Spirulina platensis, Chlorella vulgaris, and Isochrisis galbana". Journal of Food Science 68 (4): 2003.

99. Krishnakumari, M.K.; Ramesh, H.P., Venkataraman, L.V. (1981). "Food Safety Evaluation: acute oral and dermal effects of the algae Scenedesmus acutus and Spirulina platensis on albino rats". J. Food Protect. 44 (934).

100. Bizzi, A.; et al (1980). "Trattamenti prolungati nel ratto con diete conntenenti proteine di Spirulina. Aspetti biochimici, morfologici e tossicologici" [Extended Treatment of Rats with Diets Containing Spirulina. Biochemical, morphlogical, and toxicological aspects.]. In Materassi, R. Prospettive della coltura di Spirulina in Italia (Accademia dei Geo rgofili, Firence) 205.

101. The Spirulina Diet. by Saundra Howard. 1982. Pub. by Lyle Stuart, Secacus, NJ. USA.

102. a b Chamorro-Cevallos, G.; B.L. Barron, J. Vasquez-Sanchez (2008). "Toxicologic Studies and Antitoxic Properties of Spirulina". In Gershwin, M.E. Spirulina in Human Nutrition and Health (CRC Press).

103. Study on effect and mechanism of polysaccharides of spirulina on body immune function improvement. by G. Baojiang, et al. April 1994. South China Normal Univ. China. Pub. in Proc. of Second Asia Pacific Conf. on Algal Biotech. Univ. of Malaysia. pp 33-38. China.

104. Effects of polysaccharide and phycocyanin from spirulina on peripheral blood and hematopoietic system of bone marrow in mice. by Zhang Cheng-Wu, et al.. April 1994. Nanjing Univ. China. Pub. in Proc. of Second Asia Pacific Conf. on Algal Biotech. Univ. of Malaysia. p.58. China.

105. Phagocytic potential of feline macrophages after exposure to a water soluble extract of spirulina in vitro. by M. Qureshi, et al. January 1996. Pub. in Immunopharmacology. in press. USA.

106. Spirulina extracts enhances chicken macrophage functions after in vitro exposure. by M. Qureshi, et al. 1995. Pub. in Jour. Nutritional Immunology, No. 3 (4) 35-45. USA.

107. Immune enhancement potential of spirulina in chickens. by M. Qureshi, et al. August 1994. Poultry Science Assoc. Dept. of Poultry Science, North Carolina State, NC. Pub. in Journal of Poultry Science Vol 73, S.1. p. 46. USA.

108. Immunomodulary effects of spirulina supplementation in chickens. by M. Qureshi, et al. May 1995. North Carolina State. Pub. in Proc. of 44th Western Poultry Disease Conference, pp 117-120. USA.

109. Immunostimulating activity of lipopolysaccharides from blue-green algae. by L. Besednova, et al. 1979. Pub. in Zhurnal Mikrobiologii, Epidemiologii, Immunobiologii, 56(12) pp 75-79. Russia.

110. Means to normalize the levels of immunoglobulin E, using the food supplement Spirulina. by L. Evets, et al. 1994. Grodenski State Medical Univ. Russian Federation Committee of Patents and Trade. Patent (19)RU (11)2005486. Jan. 15, 1994. Russia.

111. Radioprotective effect of extract from spirulina in mouse bone marrow cells studied by using the micronucleus test. by P. Qishen, Kolman et al. 1989. In Toxicology Letters 48: 165-169. China.

112. Immune response activation in channel catfish ictaluras punctatus fed spirulina enriched artemia. by B. Portoni et al. 1996. American Fisheries Society Fish Health Section. USA.

113. Availability of iron to rats from spirulina, a blue-green algae. by P. Johnson and E. Shubert. 1986. Pub. in Nutrition Research Vol 6, 85-94. USA.

114. Belay, Amha (2008). "Spirulina (Arthrospira): Production and Quality Assurance". Spirulina in Human Nutrition and Health, CRC Press: 1"“25.

115. a b "Blue-green algae". MedlinePlus. National Institutes of Health. July 6, 2011. Retrieved October 4, 2011.

116. Earth Food Spirulina: How this remarkable blue-green algae can transform your health and our planet. by Robert Henrikson. 1989, Revised 1994. Pub. by Ronore Enterprises, Inc. PO Box 1188, Kenwood, CA 95452 USA.

117. Hayashi T. & Hayashi K., et al, Journal of Natural Products 1996, Vol. 59, No. 1, 83-87, American Chemical Society and American Society of Pharmacognosy. Calcium Spirulan, an Inhibitor of Enveloped Virus Replication, from a Blue-Green Alga Spirulina platensis.

118. McCarty, M. F. (2007). "Clinical Potential o fSpirulina as a Source of Phycocyanobilin". Journal of Medicinal Food 10 (4): 566"“570. doi:10.1089/jmf.2007.621. PMID 18158824.

119. Large scale nutritional supplementation with spirulina alga. by C.V. Seshadri. 1993. All India Coordinated Project on Spirulina. Shri Amm Murugappa Chettiar Research Center (MCRC) Madras, India.

120. Observations on the utilization of spirulina as an adjuvant nutritive factor in treating some diseases accompanied by a nutritional deficiency. by V. Fica, et al. 1984. Clinica II Medicala, Spitalui Clinic, Bucuresti. Med. Interna 36 (3). Romania. (in Romanian).

121. The study on curative effect of zinc containing spirulina for zinc deficient children. by Wen Yonghuang, et al. 1994. Capital Medical College, Beijing. Presented at 5th Int'l Phycological Congress, Qingdao, June 1994. China.

122. Antitumoral agents containing phycobilin- also used to treat ulcers and hemorrhoidal bleeding. by Dainippon Ink & Chemicals and Tokyo Kenkyukai. 1983. Patent 58065216 A 830418. Japan.

123 Effect of spirulina on the renal toxicity induced by inorganic mercury and cisplatin. by H. Fukino, et al. 1990. Pub. in Eisei Kagaku, 36:5, 1990. Japan.

124. Effects of polysaccharide and phycocyanin from spirulina on peripheral blood and hematopoietic system of bone marrow in mice. by Zhang Cheng-Wu, et al.. April 1994. Nanjing Univ. China. Pub. in Proc. of Second Asia Pacific Conf. on Algal Biotech. Univ. of Malaysia. China.

125. Calcium Spirulan, an inhibitor of enveloped virus replication, from a blue-green alga Spirulina. by Hayashi et al. 1996. Pub. in Journal of Natural Products, 59, 83-87. Japan.

126. Ayehunie, S. et al. "Inhibition of HIV-1 Replication by an Aqueous Extract of Spirulina platensis (Arthrospira platensis)." JAIDS: Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology. 18, 1, May 1998: 7-12.

127. Spirulina, Algae of Life. April 1993. Bulletin Special No. 12. Pub. by Institute Oceanographique, Monaco.

128. Barmejo-Bescós, P., Piñero-Estrada, E., &Villar del Fresno, A. (2008). "Neuroprotection by Spirulina platensis protean extract and phycocyanin against iron-induced toxicity in SH-SY5Y neuroblastoma cells". Toxicology in Vitro 22 (6): 1496"“1502. doi:10.1016/j.tiv.2008.05.004. PMID 18572379.

129. Khan M. et al. (December 2005). "Protective effect of Spirulina against doxorubicin-induced cardiotoxicity". Phytotherapy Research 19 (12): 1030"“7. doi:10.1002/ptr.1783. PMID 16372368.

130. Wang, Y., et al. "Dietary supplementation with blueberries, spinach, or spirulina reduces ischemic brain damage." Experimental Neurology. May, 2005 ;193(1):75-84.

131. Health Benefits of Spirulina. by Denise Fox. 1993. In Spirulina, Algae of Life. April 1993. Bulletin No. 12. Pub. by Institute Oceanographique, Monaco.

132. Gemma, C., et al. "Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines." Experimental Neurology. July 15, 2002; 22(14):6114-20.

133. Kulshreshtha, A., Zacharia, J., Jarouliya, U.,Bhadauriya, P., Prasad, G.B.K.S., & Bisen, P.S. (2008). "Spirulina in Health Care Management". Current Pharmaceutical Biotechnology 9 (5): 400"“405. doi:10.2174/138920108785915111. PMID 18855693.

134. "ALSUntangled No. 9: Blue-green algae (Spirulina) as a treatment for ALS". Amyotroph Lateral Scler 12 (2): 153"“5. March 2011. doi:10.3109/17482968.2011.553796. PMID 21323493.

135. Chen, LL, et al. "Experimental study of spirulina platensis in treating allergic rhinitis in rats." Journal of Central South University (Medical Sciences). Feb. 2005. 30(1):96-8.

136. Simpore, J., et al. "Nutrition Rehabilitation of HIV-Infected and HIV-Negative Undernourished Children Utilizing Spirulina." Annals of Nutrition & Metabolism. 49, 2005: 373-380.

137. Effectiveness of spirulina algae as food for children with protein-energy malnutrition in a tropical environment. by P. Bucaille. 1990. University Paul Sabatier, Toulouse, France. Oct. 1990. Zaire. (in French).

138. Mir Misbahuddin, AZM Maidul Islam, Salamat Khandker, Ifthaker-Al-Mahmud, Nazrul Islam and Anjumanara. Efficacy of spirulina extract plus zinc in patients of chronic arsenic poisoning: a randomized placebo-controlled study. (Risk factors ). Journal of Toxicology: Clinical Toxicology. 44.2 (March 2006): p135(7).

139. Prevention of experimental oral cancer by extracts of spirulina-dunaliella algae. by J. Schwartz, G. Shklar, et al. 1988. Harvard School of Dental Medicine. Pub. in Nutrition and Cancer, 11, 127-134. 1988. USA.

140. Evaluation of chemoprevention of oral cancer with spirulina. by Babu, M. et al. 1995. Pub. in Nutrition and Cancer, Vol. 24, No. 2, 197-202. India.

141. Cingi, C., Conk-Dalay, M., Cakli, H., & Bal, C. (2008). "The effects of Spirulina on allergic rhinitis". European Archives of Oto-Rhino-Larynology 265 (10): 1219"“1223. doi:10.1007/s00405-008-0642-8. PMID 18343939.

142. a b Park, H.; Lee, Y.; Ryu, H.; Kim, M.; Chung, H.; Kim, W. (2008). "A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans". Annals of nutrition & metabolism 52 (4): 322"“328. doi:10.1159/000151486. PMID 18714150.

143. Current knowledge on potential health benefits of spirulina. by Amha Belay and Yoshimichi Ota. 1993. In Journal of Appl. Phycology, 5:235-241. USA.

144. Effectiveness of spirulina algae as food for children with protein-energy malnutrition in a tropical environment. by P. Bucaille. 1990. University Paul Sabatier, Toulouse, France. Oct. 1990. Zaire. (in French).

145. Food value of spirulina in humans. by C. Sautier and J. Tremolieres. 1976. Pub. in Ann. Nutrition Alim., 30:517-534. France (in French).

146. Torres-Duran PV, Ferreira-Hermosillo A, Juarez-Oropeza MA (2007). "Antihyperlipemic and antihypertensive effects of Spirulina maxima in an open sample of Mexican population: a preliminary report". Lipids Health Dis 6: 33. doi:10.1186/1476-511X-6-33. PMC 2211748. PMID 18039384.

147. Iron transfer from spirulina to blood in rats. by K. Takemoto, et al. 1982. Saitama Medical College. Japan.

148. AIDS Antiviral sulfolipids from cyanobacteria (blue-green algae). by K. Gustafson, et al. 1989. Pub. in Journal of the National Cancer Institute, August 16, 1989, pg 1254. USA.

149. Cholesterol lowering effect of spirulina. by N. Nayaka, et al. 1988. Tokai Univ. Pub. in Nutrition Reports Int'l, Vol. 37, No. 6, 1329-1337. Japan.

150. Rejuvenating the Body through fasting with Spirulina plankton. by Christopher Hills. 1979. Pub. by Univ. of the Trees, Boulder Creek, CA. USA.

151. Lu, H.K., Hsieh, C.C. Hsu, J.J., Yang, Y.K., & Chou, H.N. (2006). "Preventative effects of Spirulina platensis on skeletal muscle damage under exercise induced oxidative stress". European Journal of Applied Physiology 98 (2): 220"“226. doi:10.1007/s00421-006-0263-0. PMID 16944194.

152. Enhancement of antibody production in mice by dietary spirulina. by Hayashi, et al. June 1994. Kagawa Nutrition Univ. Japan. Pub. in Journal of Nutr. Science and Vitaminology. Japan.

153. IIMSAM, Intergovernmental Institution for the use of Micro-algae Spirulina Against Malnutrition

154. Algoculture: Spirulina, hope for a hungry world. by Ripley D. Fox. 1986. Pub. by Edisud, Aix-en-Province, France (in French).

155. Characterization of Spirulina biomass for CELSS diet potential. Normal, Al.: Alabama A&M University, 1988.

156. Jensen GS, Ginsberg DI, Drapeau C. Blue-green algae as an immuno-enhancer and biomodulator. J Amer Nutraceut Assoc 2001;3(4):24-30.

157. Mani UV, Desai S, Iyer U. Studies on the long-term effect of spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients. J Nutraceut 2000;2(3):25-32.

158. Spirulina National Symposium (India). by C.V. Seshadri and N. Jeeji Bai. 1992. Pub. by MDRC, Madras, India.

159. Spirulina- natural sorbent of radionucleides. by L.P. Loseva and I.V. Dardynskaya. Sep 1993. Research Institute of Radiation Medicine, Minsk, Belarus. 6th Int'l Congress of Applied Algology, Czech Republic. Belarus.

160. Spirulina in Jiangxi China. by Miao Jian Ren. 1987. Academy of Agricultural Science. Presented at Soc. Appl. Algology, Lille France Sep. 1987. China.

161. The study on curative effect of zinc containing spirulina for zinc deficient children. by Wen Yonghuang, et al. 1994. Capital Medical College, Beijing. Presented at 5th Int'l Phycological Congress, Qingdao, June 1994. China.

162. Clinical and biochemical evaluations of spirulina with regard to its application in the treatment of obesity. by E.W. Becker, et al. 1986. Inst. Chem. Pfanz. Pub. in Nutrition Reports Int'l, Vol. 33, No. 4, pg 565. Germany.

163. Bioavailability of spirulina carotenes in preschool children. by V. Annapurna, et al. 1991. National Institute of Nutrition, Hyderabad, India. J. Clin. Biochem Nutrition. 10 145-151. India.

164. Large scale nutritional supplementation with spirulina alga. by C.V. Seshadri. 1993. All India Coordinated Project on Spirulina. Shri Amm Murugappa Chettiar Research Center (MCRC) Madras, India.

165. Samuels R, Mani UV, Iyer UM, et al. Hypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndrome. J Med Food 2002;5(2):91-96.

166. Shih SR, Tsai KN, Li YS, et al. Inhibition of enterovirus 71-induced apoptosis by allophycocyanin isolated from a blue-green alga Spirulina platensis. J.Med.Virol. 2003;70(1):119-125.

167. Effects of spirulina on plasma lipoprotein lipase activity in rats. by K. Iwata. 1990. Pub. in Journal Nutr. Sci. Vitaminol. 36:165-171. Japan.

168. Clinical experiences of administration of spirulina to patients with hypochronic anemia. by T. Takeuchi, et al. 1978. Tokyo Medical and Dental Univ. Japan.

169. Effect of spirulina on the renal toxicity induced by inorganic mercury and cisplatin. by H. Fukino, et al. 1990. Pub. in Eisei Kagaku, 36:5, 1990. Japan.

170. The effect of spirulina on nephrotoxicity in rats. by Y. Yamane, et al. 1988. Chiba Univ. Presented at Annual Symposium of the Pharmaceutical Society of Japan, April 15, 1988. Japan.

Chlorella

Chlorella.jpeg
  1. Borowitzka MA. In: Micro-algal biotechnology. Borowitzka LJ, editor. New York: Cambridge University Press; 1988. Vitamins and fine chemicals from micro-algae; p. 153.

  2. 5. “Changes induced by Chlorella on the Body Weight and incidence of Colds Among Naval Trainees.” Midorf, 1, 1970.

  3. Schubert LE. In: Progressing physiological research. Round FE, Chapman DJ, editor. Bristol, U.K: Biopress Ltd; 1988. The use of spirulina and chlorella as food resource for animals and humans; p. 23.

  4. Toru Mizoguchi, Isao Takehara, Tohru Masuzawa, Toshiro Saito, and Yo Naoki.Journal of Medicinal Food.Sep 2008.391-404 Volume: 11 Issue 3: Beyond Fish Oil Supplementation: The Effects of Alternative Plant Sources of Omega-3 Polyunsaturated Fatty Acids upon Lipid Indexes and Cardiometabolic Biomarkers—An Overview

  5. Panahi Y, Mostafazadeh B, Abrishami A, Saadat A, Beiraghdar F, Tavana S, Pishgoo B, Parvin S, Sahebkar A. Investigation of the effects of Chlorella vulgaris supplementation on the modulation of oxidative stress in apparently healthy smokers. Clin Lab. 2013;59(5-6):579-87.

  6. Lee SH, Kang HJ, Lee HJ, Kang MH, Park YK. Six-week supplementation with Chlorella has favorable impact on antioxidant status in Korean male smokers. Nutrition. 2010 Feb;26(2):175-83.

  7. Tsiplakou E, Abdullah MAM, Mavrommatis A, Chatzikonstantinou M, Skliros D, Sotirakoglou K, Flemetakis E, Labrou NE, Zervas G. The effect of dietary Chlorella vulgaris inclusion on goat's milk chemical composition, fatty acids profile and enzymes activities related to oxidation.  J Anim Physiol Anim Nutr (Berl). 2018 Feb;102(1):142-151.

  8. Ferrazzano GF, Papa C, Pollio A, Ingenito A, Sangianantoni G, Cantile T.Cyanobacteria and Microalgae as Sources of Functional Foods to Improve Human General and Oral Health. Molecules. 2020 Nov 6;25(21):5164.

  9. Neumann U, Derwenskus F, Gille A, Louis S, Schmid-Staiger U, Briviba K, Bischoff SC. Bioavailability and Safety of Nutrients from the Microalgae Chlorella vulgaris, Nannochloropsis oceanica and Phaeodactylum tricornutum in C57BL/6 Mice. Nutrients. 2018 Jul 26;10(8):965.

  10. Rzymski P, Jaśkiewicz M. Microalgal food supplements from the perspective of Polish consumers: patterns of use, adverse events, and beneficial effects.  J Appl Phycol. 2017;29(4):1841-1850.

  11. Mohd Azamai ES, Sulaiman S, Mohd Habib SH, et al. Chlorella vulgaris triggers apoptosis in hepatocarcinogenesis-induced rats. J Zhejiang Univ Sci B. 2009;10(1):14-21. doi:10.1631/jzus.B0820168

  12. Zainul Azlan N, Mohd Yusof YA, Makpol S. Chlorella vulgaris Ameliorates Oxidative Stress and Improves the Muscle Regenerative Capacity of Young and Old Sprague-Dawley Rats. Nutrients. 2020;12(12):3752. Published 2020 Dec 7. doi:10.3390/nu12123752

  13. Zainul Azlan N, Mohd Yusof YA, Alias E, Makpol S. Chlorella vulgaris Modulates Genes and Muscle-Specific microRNAs Expression to Promote Myoblast Differentiation in Culture. Evid Based Complement Alternat Med. 2019;2019:8394648. Published 2019 Jul 21. doi:10.1155/2019/8394648

  14. Mizoguchi T, Takehara I, Masuzawa T, Saito T, Naoki Y. Nutrigenomic studies of effects of Chlorella on subjects with high-risk factors for lifestyle-related disease. J Med Food. 2008 Sep;11(3):395-404. doi: 10.1089/jmf.2006.0180. PMID: 18800884

  15. Noguchi N, Konishi F, Kumamoto S, Maruyama I, Ando Y, Yanagita T. Beneficial effects of Chlorella on glucose and lipid metabolism in obese rodents on a high-fat diet. Obes Res Clin Pract. 2013 Mar-Apr;7(2):e95-e105. doi: 10.1016/j.orcp.2013.01.002. PMID: 24331771

  16. Makpol, Suzana et al. “Chlorella Vulgaris Modulates Hydrogen Peroxide-Induced DNA Damage and Telomere Shortening of Human Fibroblasts Derived from Different Aged Individuals.” African Journal of Traditional, Complementary, and Alternative Medicines 6.4 (2009): 560–572.

  17. 2. Merchant, Randall et al. “Dietary Chlorella pyrenoidosa for patients with malignant glioma: Effects on immunocompetence, quality of life, and survival.” Phytother. Res., 4 (1990): 220–231. doi:10.1002/ptr.2650040605

  18. 3. The diverse effects of chlorella, Management, Menu for Mass Feeding, June 1966, reprinted by Scientific Reports on Chlorella in Japan, Silpaque Pulbishing.

  19. 4. Kwak, Jung Hyun et al. “Beneficial Immunostimulatory Effect of Short-Term Chlorella Supplementation: Enhancement of Natural Killer Cell Activity and Early Inflammatory Response (Randomized, Double-Blinded, Placebo-Controlled Trial).” Nutrition Journal 11 (2012): 53.

  20. 6. Dr. Paul Tse A.H.C.M., C.E.T., C.T., R.Ac. “The Detoxification, Immunostimulation and Healing Property of Chlorella.” World Convention of Traditional Medicine & Acupuncture, March 2000.

  21. Zainul Azlan N, Mohd Yusof YA, Alias E, Makpol S. Chlorella vulgaris improves the Regenerative Capacity of Young and Senescent Myoblasts and Promotes Muscle Regeneration. Oxid Med Cell Longev. 2019; 2019:3520789. Published 2019 Jun 4.

  22. Morita K, Matsueda T, Lida T, Hasegawa T. Chlorella accelerates dioxin excretion in rats. J Nutr. 1999; 129:1731–1736.

  23. Morita K, Ogata K, Hasegawa T. Chlorophyll derived from Chlorella inhibits dioxin absorption from the gastrointestinal tract and accelerates dioxin excretion in rats. Environ Health Perspect. 2001;109:289–294. Okudo M, Hasegawa T, Sonoda M, Okabe T, Tanaka M. The effects of Chlorella on the level of cholesterol in serum and liver. Jpn J Nutr. 1975;33:3–8.

  24. Fujiwara Y, Hirakawa K, Sinpo K. Effect of long-term administration of Chlorella tablets on hyperlipemia. J Jpn Soc Nutr Food Sci. 1990;43:167–173.

  25. Nakamura T, Hasegawa T, Ueno S. et al. Effect of g-aminobutyric acid-rich Chlorella on blood pressure in mildly hypertensive subjects. Jpn Pharmacol Ther. 2000;28:529–533.

  26. Queiroz ML, Bincoletto C, Valadares MC, Dantas DC, Santos LM. Effects of Chlorella vulgaris extract on cytokines production in Listeria monocytogenes infected mice. Immunopharmacol Immunotoxicol. 2002;24:483–496.

  27. Hasegawa T, Matsuguchi T, Noda K, Tanaka K, Kumamoto S, Shoyama Y, Yoshikai Y. Toll-like receptor 2 is at least partly involved in the antitumor activity of glycoprotein from Chlorella vulgaris. Int Immunopharmacol. 2002;2:579–589.

  28. Tanaka K, Yamada A, Noda K, Hasegawa T, Okuda K, Shoyama Y, Nomoto K. A novel glycoprotein obtained from Chlorella vulgaris strain CK22 shows antimetastatic immunopotentiation. Cancer Immunol Immunother. 1998;45:313–320

  29. Shibata S, Natori Y, Nishihara T, Tomisaka K, Matsubara K, Sanawa H, Nguyen VC. Antioxidant and anticataract effect of Chlorella on rats with streptozotocin-induced diabetes. J Nutr Sci Vitaminol. 2003;49:334–339.

  30. Rodriguez-Lopez M, Lopez-Quijada C. Plasma glucose and plasma insulin in normal and alloxanized rats treated with Chlorella. Life Sci. 1971;10:57–68.

  31. Lee HS, Choi CY, Cho C, Song Y. Attenuating effect of chlorella supplementation on oxidative stress and NF kappa B activation in peritoneal macrophages and liver of C57BL/6 mice fed on an atherogenic diet. BiosciBiotechnol Biochem. 2003;67:2083–2090.

  32. Tanaka K, Yamada A, Nada K, Shoyama Y, Kubo C, Nomoto K. Oral administration of a unicellular green algae, Chlorella vulgaris, prevents stress-induced ulcer. Plant Med. 1997;63:465–466.

  33. Tanaka K, Konishi F, Himeno K, Taniguchi K, Nomoto K. Augmentation of antitumor resistance by a strain of unicellular green algae, Chlorella vulgaris. Cancer Immunol Immunother. 1984;17:90–94.

  34. Konishi F, Tanaka K, Himeno K, Taniguchi K, Nomoto K. Antitumor effect induced by a hot water extract of Chlorella vulgaris (CE): resistance to Meth-A tumor growth mediated by CE-induced polymorphonuclear leukocytes. Cancer Immunol Immunother. 1985;19:73–78.

  35. Tanaka K, Tomita Y, Tsuruta M. et al.Oral administration of Chlorella vulgaris augments concomitant antitumor immunity. Immunopharmacol Immunotoxicol. 1990;12:277-21

  36. Tanaka K, Koga T, Konishi F. Augmentation of host defense by a unicellular green alga, Chlorella vulgaris, to Escherichia coli infection. Infect Immun. 1986;53:267–271.

  37. Hasegawa T, Tanaka K, Ueno K. Augmentation of the resistance against Escherichia coli by oral administration of a hot water extract of Chlorella vulgaris in rats. Int J Immunopharmacol. 1989;11:971–976.

  38. Hasegawa T, Okuda M, Nomoto K, Yoshikai Y. Augmentation of the resistance against Listeria monocytogenes by oral administration of a hot water extract of Chlorella vulgaris in mice. Immunopharmacol Immunotoxicol. 1994;16:191–202.

  39. Hasegawa T, Okuda M, Makino M, Hiromatsu K, Nomoto K, Yoshikai Y. Hot water extracts of Chlorella vulgaris reduce opportunistic infection with Listeria monocytogenes in C57BL/6 mice infected with LP-BM5 murine leukemia viruses. Int J Immunopharmacol. 1995;17:505–512.

  40. Ibusuki K, Minamishima Y. Effect of Chlorella vulgaris extracts on murine cytomegalovirus infections. Nat Immun Cell Growth Regul. 1990;9:121–128

  41. Hasegawa T, Ito K, Ueno S. et al.Oral administration of hot water extracts of Chlorella vulgaris reduces IgE production against milk casein in mice. Int J Immunopharmacol. 1999;21:311–323.

  42. Shim JA, Son YA, Park JM, Kim MK. Effect of Chlorella intake on Cadmium metabolism in rats. Nutr Res Pract. 2009 Spring;3(1):15-22.

  43. · Kim YJ, Kwon S, Kim MK. Effect of Chlorella vulgaris intake on cadmium detoxification in rats fed cadmium. Nutr Res Pract. 2009 Summer;3(2):89-94.

  44. Shim JY, Shin HS, Han JG, Park HS, Lim BL, Chung KW, Om AS Protective effects of Chlorella vulgaris on liver toxicity in cadmium-administered rats. J Med Food. 2008 Sep;11(3):479-85.

  45. Kim MY, Shon WJ, Park MN, Lee YS, Shin DM Protective effect of dietary chitosan on cadmium accumulation in rats. Nutr Res Pract. 2016 Feb;10(1):19-25.

  46. Ogawa K, Fukuda T, Han J, Kitamura Y, Shiba K, Odani A. Evaluation of Chlorella as a Decorporation Agent to Enhance the Elimination of Radioactive Strontium from Body. PLoS One. 2016 Feb 1;11(2):e0148080.

  47. Kim YJ, Kwon S, Kim MK. Effect of Chlorella vulgaris intake on cadmium detoxification in rats fed cadmium. Nutr Res Pract. 2009 Summer;3(2):89-94.

  48. Queiroz ML, Rodrigues AP, Bincoletto C, Figueirêdo CA, Malacrida S. Protective effects of Chlorella vulgaris in lead-exposed mice infected with Listeria monocytogenes. Int Immunopharmacol. 2003 Jun;3(6):889-900.

  49. Lin SH, Li MH, Chuang KA, Lin NH, Chang CH, Wu HC, Chao YH, Lin CC, Pan IH, Perng MD, Wen SF.  Chlorella sorokiniana Extract Prevents Cisplatin-Induced Myelotoxicity In Vitro and In Vivo. Oxid Med Cell Longev. 2020 Jan 25;2020:7353618.

  50. Ogawa K, Fukuda T, Han J, Kitamura Y, Shiba K, Odani A Evaluation of Chlorella as a Decorporation Agent to Enhance the Elimination of Radioactive Strontium from Body. PLoS One. 2016 Feb 1;11(2):e0148080.

  51. Makpol S, Yeoh TW, Ruslam FA, Arifin KT, Yusof YA. Comparative effect of Piper betle, Chlorella vulgaris and tocotrienol-rich fraction on antioxidant enzymes activity in cellular ageing of human diploid fibroblasts. BMC Complement Altern Med. 2013 Aug 16;13:210. doi: 10.1186/1472-6882-13-210. PMID: 23948056 Free PMC article.

  52. Chou NT, Cheng CF, Wu HC, Lai CP, Lin LT, Pan IH, Ko CH. Chlorella sorokiniana-Induced Activation and Maturation of Human Monocyte-Derived Dendritic Cells through NF-κB and PI3K/MAPK Pathways. Evid Based Complement Alternat Med. 2012;2012:735396.

  53. Michael A. Borowitzka, Microalgae in Medicine and Human Health, Microalgae in Health and Disease Prevention, 10.1016/B978-0-12-811405-6.00009-8, (195-210), (2018).

  54. Dayana Priyadharshini Stephen, Bakthavatsalam Kannappan Ayalur, Effect of nutrients on Chlorella pyrenoidosa for treatment of phenolic effluent of coal gasification plant, Environmental Science and Pollution Research, 10.1007 2017

  55. Aline Lisie Ramos, Cristiane Okuda Torello, Mary L. S. Queiroz, Chlorella vulgaris Modulates Immunomyelopoietic Activity and Enhances the Resistance of Tumor-Bearing Mice , Nutrition and Cancer, 2010.8 1170-1180

  56. Luisa Gouveia, Ana Evangelista Marques, João M. Sousa, Patrícia Moura, Narcisa M. Bandarra. Microalgae – source of natural bioactive molecules as functional ingredients, Food Science & Technology Bulletin: Functional Foods, 10.1616/1476-2137.15884, 7, 2, (21-37), (2010).

  57. Randall E. Merchant, Cynthia A. Andre, Christopher M. Wise, Nutritional Supplementation with Chlorella pyrenoidosa for Fibromyalgia Syndrome: A Double-Blind, Placebo-Controlled, Crossover Study. Journal of Musculoskeletal Pain 2010.9 37-54

  58. Anthony G. Day, David Brinkmann, Scott Franklin, Karen Espina, George Rudenko, Ashley Roberts, Kerry S. Howse, Safety evaluation of a high-lipid algal biomass from Chlorella protothecoides. Regulatory Toxicology and Pharmacology. 2009. 55; 166-180

  59. Saburo Hidaka, Yoshizo Okamoto, Masaki Arita, A hot water extract of Chlorella pyrenoidosa reduces body weight and serum lipids in ovariectomized rats, Phytotherapy Research. 2004. 18; 164-168

  60. Randall E. Merchant, Cynthia A. Andre, Domenic A. Sica, Nutritional Supplementation with Chlorella pyrenoidosa for Mild to Moderate Hypertension. Journal of Medicinal Food. 2002. 5; 141-152

  61. Randall E. Merchant, Cynthia A. Andre, Domenic A. Sica, Chlorella Supplementation for Controlling Hypertension: A Clinical Evaluation, Alternative and Complementary Therapies. 2002. 8; 370-376

  62. Randall E. Merchant, Cynthia A. Carmack, Christopher M. Wise, Nutritional Supplementation with Chlorella pyrenoidosa for patients with fibromyalgia syndrome: a pilot study. Phytotherapy Research 2000. 14; 167-173

  63. Kiyoshi Noda, Naohito Ohno, Kuniaki Tanaka, Masao Okuda, Toshiro Yadomae, Kikuo Nomoto, Yukihiro Shoyama, A new type of biological response modifier from Chlorella vulgaris which needs protein moiety to show an antitumour activity. Phytotherapy Research 1998.12; 309-319

  64. Christian JL, Greger JL. Nutrition for Living. Redwood City, CA: Benjamin/ Cummings; 1994. p. 111.

  65. The American Dietetic Association. Handbook of Clinical Dietetics. 2. New Haven, CT: Yale University Press; 1992. pp. 5–39.

  66. Nair MP, Kandaswami C, Mahajan S. et al.The flavonoid, quercetin, differentially regulates Th-1 (IFNgamma) and Th-2 (IL4) cytokine gene expression by normal peripheral blood mononuclear cells. BiochimBiophys Acta. 2002;1593:29–36.

  67. Hasegawa T, Kimura Y, Hiromatsu K. et al. Effect of hot water extract of Chlorella vulgaris on cytokine expression patterns in mice with murine acquired immunodeficiency syndrome after infection with Listeria monocytogenes. Immunopharmacology. 1997;35: 273–282

  68. Ewart HS, Bloch O, Girouard GS. et al.Stimulation of cytokine production in human peripheral blood mononuclear cells by an aqueous Chlorella extract. Planta Med. 2007;73:762–768.

  69. Cheng FC, Lin A, Feng JJ, Mizoguchi T, Takekoshi H, Kubota H, Kato Y, Naoki Y. Effects of Chlorella on Activities of Protein Tyrosine Phosphatases, Matrix Metalloproteinases, Caspases, Cytokine Release, B and T Cell Proliferations, and Phorbol Ester Receptor Binding. J Med Food. 2004;7:146–152.

  70. Kwak JH, Baek SH, Woo Y, et al. Beneficial immunostimulatory effect of short-term Chlorella supplementation: enhancement of natural killer cell activity and early inflammatory response (randomized, double-blinded, placebo-controlled trial). Nutr J. 2012; 11:53. Published 2012 Jul 31

Beetroot

beetroot.png

1. Beta vulgaris L. USDA, NRCS. 2008. The PLANTS Database (http://plants.usda.gov ,July 2008). National Plant Data Center , Baton Rouge, LA 70874-4490 USA.

2. Chevallier A. The Encyclopedia of Medicinal Plants . Dorling Kindersley: London; 1996.

3. Fugh-Berman A, Balick MJ, Kronenberg F, et al. Treatment of fibroids: the use of beets ( Beta vulgaris ) and molasses ( Saccharum officinarum ) as an herbal therapy by Dominican healers in New York City. J Ethnopharmacol . 2004;92(2-3):337-339.

4. Lee CH, Wettasinghe M, Bolling BW, Ji LL, Parkin KL. Betalains, phase II enzyme-inducing components from red beetroot ( Beta vulgaris L.) extracts. Nutr Cancer . 2005;53(1):91-103.

5. Stintzing FC, Carle R. Functional properties of anthocyanins and betalains in plants, food, and in human nutrition. Trends Food Sci Technol . 2004;15(1):19-38.

6. Iglesias R, Pérez Y, de Torre C, et al. Molecular characterization and systemic induction of single-chain ribosome-inactivating proteins (RIPs) in sugar beet ( Beta vulgaris ) leaves. J Exp Bot . 2005;56(416):1675-1684.

7. Blázovics A, Sárdi E, Szentmihályi K, Váli L, Takács-Hájos M, Stefanovits-Bányai E. Extreme consumption of Beta vulgaris var. rubra can cause metal ion accumulation in the liver. Acta Biol Hung . 2007;58(3):281-286.

8. Ninfali P, Bacchiocca M, Antonelli A, et al. Characterization and biological activity of the main flavonoids from Swiss Chard ( Beta vulgaris subspecies cycla ). Phytomedicine . 2007;14(2-3):216-221.

9. Frank T, Stintzing FC, Carle R, et al. Urinary pharmacokinetics of betalains following consumption of red beet juice in healthy humans. Pharmacol Res . 2005;52(4):290-297.

10. Kanner J, Harel S, Granit R. Betalains"”a new class of dietary cationized antioxidants. J Agric Food Chem . 2001:49(11):5178-5185.

11. Pavlov A, Kovatcheva P, Tuneva D, Ilieva M, Bley T. Radical scavenging activity and stability of betalains from Beta vulgaris hairy root culture in simulated conditions of human gastrointestinal tract. Plant Foods Hum Nutr . 2005;60(2):43-47.

12. Sembries S, Dongowski G, Mehrländer K, Will F, Dietrich H. Physiological effects of extraction juices from apple , grape, and red beet pomaces in rats. J Agric Food Chem . 2006;54(26):10269-10280.

13. Váli L, Stefanovits-Bányai E, Szentmihályi K, et al. Liver-protecting effects of table beet ( Beta vulgaris var. rubra ) during ischemia-reperfusion. Nutrition . 2007;23(2):172-178.

14. Webb AJ, Patel N, Loukogeorgakis S, et al. Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension . 2008;51(3):784-790.

15. Minciullo PL, Mistrello G, Patafi M, Zanoni D, Gangemi S. Cross-reactivity between Parietaria pollen and beet. Allergol Immunopathol (Madr). 2007;35(2):74-75.

16. "Sorting Beta names". Multilingual Multiscript Plant Name Database. The University of Melbourne. Archived from the original on 2013-04-15. Retrieved 2013-04-15.

17. a b c Grubben, G.J.H. & Denton, O.A. (2004) Plant Resources of Tropical Africa 2. Vegetables. PROTA Foundation, Wageningen; Backhuys, Leiden; CTA, Wageningen.

18. Francis, F.J. (1999). Colorants. Egan Press. ISBN 1-891127-00-4.

19. Making Wild Wines & Meads; Pattie Vargas & Rich Gulling; page 73.

20. a b A.D.A.M., Inc., ed. (2002), Betaine, University of Maryland Medical Center.

21. Homocysteine or Renal Impairment Which Is the Real Cardiovascular Risk Factor?, Potter et al, Arteriosclerosis, Thrombosis, and Vascular Biology. 2008; 28: 1158-1164.

22. Engan, Harald; Andrew M. Jones, Fanny Ehrenberg, Erika Schagatay (12). Respiratory Physiology & Neurobiology 182 (2-3) http://www.sciencedirect.com/science/article/pii/S1569904812001036 |url= missing title (help).

23. Webb, Andrew J.; Nakul Patel; Stavros Loukogeorgakis; Mike Okorie; Zainab Aboud; Shivani Misra; Rahim Rashid; Philip Miall; John Deanfield; Nigel Benjamin; Raymond MacAllister; Adrian J. Hobbs; Amrita Ahluwalia; Patel, N; Loukogeorgakis, S; Okorie, M; Aboud, Z; Misra, S; Rashid, R; Miall, P et al. (2008), "Acute Blood Pressure Lowering, Vasoprotective, and Antiplatelet Properties of Dietary Nitrate via bioconversion to Nitrite", Hypertension 51 (3): 784"“790, doi:10.1161/HYPERTENSIONAHA.107.103523, PMC 2839282, PMID 18250365.

24. "Beet your personal best". Sydney Morning Herald. 4 October 2010. Archived from the original on 6 October 2010. Retrieved 5 October 2010.

25. Stephen Nottingham (2004), Beetroot (E-book)

Carrot

carrot.png

1. Agte V, Jahagirdar M, Chiplonkar S. GLV supplements increased plasma beta-carotene, vitamin C, zinc and hemoglobin in young healthy adults. Eur J Nutr 2006;45(1):29-36.
2. Briviba K, Schnabele K, Rechkemmer G, et al. Supplementation of a diet low in carotenoids with tomato or carrot juice does not affect lipid peroxidation in plasma and feces of healthy men. J Nutr 2004;134(5):1081-1083 .
3. Bub A., Barth SW, Watzl B, et al. Paraoxonase 1 Q192R (PON1-192) polymorphism is associated with reduced lipid peroxidation in healthy young men on a low-carotenoid diet supplemented with tomato juice. Br J Nutr 2005;93(3):291-297.
4. Cardinault N, Tyssandier V, Grolier P, et al. Comparison of the postprandial chylomicron carotenoid responses in young and older subjects. Eur J Nutr 2003;42(6):315-323.
5. Donaldson MS, Speight N, Loomis S. Fibromyalgia syndrome improved using a mostly raw vegetarian diet: an observational study. BMC.Complement Altern Med 2001;1:7.
6. el Arab AE, Khalil F, Hussein L. Vitamin A deficiency among preschool children in a rural area of Egypt: the results of dietary assessment and biochemical assay. Int J Food Sci Nutr 2002;53(6):465-474.
7. Gerrish CJ, Mennella JA. Flavor variety enhances food acceptance in formula-fed infants. Am J Clin Nutr 2001;73(6):1080-1085.
8. Horvitz MA, Simon PW, Tanumihardjo SA. Lycopene and beta-carotene are bioavailable from lycopene 'red' carrots in humans. Eur J Clin Nutr 2004;58(5):803-811.
9. Kurilich AC, Clevidence BA, Britz SJ, et al. Plasma and urine responses are lower for acylated vs nonacylated anthocyanins from raw and cooked purple carrots. J Agric.Food Chem 8-10-2005;53(16):6537-6542 .
10. Moller P, Loft S. Oxidative DNA damage in human white blood cells in dietary antioxidant intervention studies. Am J Clin Nutr 2002;76(2):303-310 .
11. Ncube TN, Greiner T, Malaba LC, et al. Supplementing lactating women with pureed papaya and grated carrots improved vitamin A status in a placebo-controlled trial. J Nutr 2001;131(5):1497-1502 .
12. Thurmann PA, Steffen J, Zwernemann C, et al. Plasma concentration response to drinks containing beta-carotene as carrot juice or formulated as a water dispersible powder. Eur J Nutr 2002;41(5):228-235 .
13. Tyssandier V, Reboul E, Dumas JF, et al. Processing of vegetable-borne carotenoids in the human stomach and duodenum. Am J Physiol Gastrointest.Liver Physiol 2003;284(6):G913-G923 .
14. Vieths S, Scheurer S, Ballmer-Weber B. Current understanding of cross-reactivity of food allergens and pollen. Ann.N Y.Acad.Sci 2002;964:47-68 .
15. Watzl B, Bub A, Briviba K, et al. Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men. Ann.Nutr Metab 2003;47(6):255-261.
16. Agricultural Marketing Resource Center (AgMRC). Carrot Profile. 2011;Iowa State University, Ames, IO. Available online at: http://www.agmrc.org. 0.
17. de Jesus Ornelas-Paz J , Yahia EM and Gardea-Bejar AA. Bioconversion Efficiency of B-Carotene from Mango Fruit and Carrots. Vitamin A Journal: American Journal of Agricultural and Biological Science Year: 2010 Vol: 5 Issue: 3 Pages/record No.: 301-308. 2010 .
18. Imsic M, Winkler S, Tomkins B et al. Effect of storage and cooking on beta-carotene isomers in carrots ( Daucus carota L. cv. 'Stefano'). J Agric Food Chem. 2010 Apr 28;58(8):5109-13. 2010 .

19. Kjellenberg L, Johansson E, Gustavsson KE et al. Effects of harvesting date and storage on the amounts of polyacetylenes in carrots, Daucus carota. J Agric Food Chem. 2010 Nov 24;58(22):11703-8. Epub 2010 Oct 21. 2010.
20. Lemmens L, Colle IJ, Van Buggenhout S et al. Quantifying the influence of thermal process parameters on in vitro B-carotene bioaccessibility: a case study on carrots. J Agric Food Chem. 2011 Apr 13;59(7):3162-7. Epub 2011 Mar 15. 2011.
21. Lin BH and Lucier G. Carrot Consumption Varies With Age, Income, and Race. Amber Waves. Washington: Apr 2008. Vol. 6, Iss. 2; p. 4. 2008 .
22. Matejkova J and Petrikova K. Variation in Content of Carotenoids and Vitamin C in Carrots . Notulae Scientia Biologicae Year: 2010 Vol: 2 Issue: 4 Pages/record No.: 88-91. 2010 .
23. Metzger BT and Barnes DM. Polyacetylene diversity and bioactivity in orange market and locally grown colored carrots (Daucus carota L.). J Agric Food Chem. 2009 Dec 9;57(23):11134-9. 2009 .
24. Morizet D, Depezay L, Masse P et al. Perceptual and lexical knowledge of vegetables in preadolescent children. Appetite. 2011 Aug;57(1):142-7. Epub 2011 Apr 16. 2011.
25. Neri L, Hernando Hernando I, Perez-Munuera I et al. Effect of blanching in water and sugar solutions on texture and microstructure of sliced carrots. J Food Sci. 2011 Jan-Feb;76(1):E23-30. doi: 10.1111/j.1750-3841.2010.01906.x. Epub 2010 Nov 29. 2011.
26. Nicolle C, Simon G, Rock E et al. Genetic Variability Influences Carotenoid, Vitamin, Phenolic, and Mineral Content in White, Yellow, Purple, Orange, and Dark-orange Carrot Cultivars. J. Amer. Soc. Hort. Sci., Jul 2004; 129: 523-529. 2004 .
27. Oude Griep LM, Monique Verschuren WM, Kromhout D et al. Colours of fruit and vegetables and 10-year incidence of CHD. Br J Nutr. 2011 Jun 8:1-8. [Epub ahead of print]. 2011 .
28. Purup S, Larsen E and Christensen LP. Differential Effects of Falcarinol and Related Aliphatic C17-Polyacetylenes on Intestinal Cell Proliferation. J Agric Food Chem. 2009 September 23; 57(18): 8290"“8296. 2009 .
29. Rennie C and Wise A. Preferences for steaming of vegetables. J Hum Nutr Diet. 2010 Feb;23(1):108-10. Epub 2009 Nov 23. 2010 .
30. Soltoft M, Bysted A, Madsen KH et al. Effects of organic and conventional growth systems on the content of carotenoids in carrot roots, and on intake and plasma status of carotenoids in humans. J Sci Food Agric. 2011 Mar 15;91(4):767-75. doi: 10.1002/jsfa.4248. Epub 2011 Jan 6. 2011.
31. Tang G. Bioconversion of dietary provitamin A carotenoids to vitamin A in humans. Am J Clin Nutr. 2010 May;91(5):1468S-1473S. Epub 2010 Mar 3. 2010.
32. Theodosiou M, Laudet V and Schubert M. . From carrot to clinic: an overview of the retinoic acid signaling pathway. Cellular and Molecular Life Sciences. Basel: May 2010. Vol. 67, Iss. 9; p. 1423-1445. 2010 .
33. Wang ZX, Dong PC, Sun TT et al. [Comparison of lutein, zeaxanthin and B-carotene level in raw and cooked foods consumed in Beijing]. Zhonghua Yu Fang Yi Xue Za Zhi. 2011 Jan;45(1):64-7. Chinese. 2011.
34. http://curecancercells.com/carrot-juice/
35. http://www.carrotmuseum.co.uk/falcarinol.html
36. http://www.naturalnews.com/042513_carrots_surprising_facts_health_benefits.html
37. http://myhealthbynature.com/carrot-juice-benefits-side-effects/
38. Zidorn C, Johrer K, Ganzera M et al. Polyacetylenes from the Apiaceae vegetables carrot, celery, fennel, parsley, and parsnip and their cytotoxic activities. J Agric Food Chem. 2005 Apr 6;53(7):2518-23. 2005.

39. http://www.ars-grin.gov/duke/

40. http://ndb.nal.usda.gov/ndb/foods

Red Raspberry

closeup-shot-cute-fresh-raspberries-one-

1. World's Healthiest Foods, in-depth nutrient profile for raspberries. Whfoods.org. Retrieved on 2012-09-24.
2. Journal of Agricultural and Food Chemistry Presents Research from the 2007 International Berry Health Benefits Symposium, Journal of Agricultural and Food Chemistry ACS Publications, February 2008
3. Carvalho, Elisabete; Fraser, P.D.; Martens, S. (2013). ""Carotenoids and tocopherols in yellow and red raspberries"". Food Chemistry 139: 744""“752. doi:10.1016/j.foodchem.2012.12.047.
4. Liu M, Li XQ, Weber C, Lee CY, Brown J, Liu RH (May 2002). ""Antioxidant and antiproliferative activities of raspberries"". J. Agric. Food Chem. 50 (10): 2926""“30. doi:10.1021/jf0111209. PMID 11982421.
5. Heinonen M (June 2007). ""Antioxidant activity and antimicrobial effect of berry phenolics""”a Finnish perspective"". Mol Nutr Food Res 51 (6): 684""“91. doi:10.1002/mnfr.200700006. PMID 17492800.
6. Cerdá B, Tomás-Barberán FA, Espín JC (January 2005). ""Metabolism of antioxidant and chemopreventive ellagitannins from strawberries, raspberries, walnuts, and oak-aged wine in humans: identification of biomarkers and individual variability"". J. Agric. Food Chem. 53 (2): 227""“35. doi:10.1021/jf049144d. PMID 15656654.
7. ""Statistics from: Food And Agricultural Organization of United Nations: Economic And Social Department: The Statistical Division"". UN Food and Agriculture Organization Corporate Statistical Database.
8. Aiyer HS, Li Y, Liu QH et al. Dietary freeze-dried black raspberry's effect on cellular antioxidant status during reflux-induced esophagitis in rats. Nutrition, Volume 27, Issue 2, February 2011, Pages 182-187.
9. Ali L, Svensson B, Alsanius BW et al. Late season harvest and storage of Rubus berries-Major antioxidant and sugar levels. Scientia Horticulturae, Volume 129, Issue 3, 27 June 2011, Pages 376-381.
10. Beekwilder J, Hall RD and de Vos CH. Identification and dietary relevance of antioxidants from raspberry. Biofactors. 2005;23(4):197-205. 2005.
11. Bobinaite R, Viskelis P and Venskutonis PR. Variation of total phenolics, anthocyanins, ellagic acid and radical scavenging capacity in various raspberry (Rubus spp.) cultivars. Food Chemistry, Volume 132, Issue 3, 1 June 2012, Pages 1495-1501.
12. Borquez RM, Canales ER and Redon JP. Osmotic dehydration of raspberries with vacuum pretreatment followed by microwave-vacuum drying. Journal of Food Engineering, Volume 99, Issue 2, July 2010, Pages 121-127.
13. Bowen-Forbes CS, Zhang Y and Nair MG. Anthocyanin content, antioxidant, anti-inflammatory and anticancer properties of blackberry and raspberry fruits. Journal of Food Composition and Analysis, Volume 23, Issue 6, September 2010, Pages 554-560.
14. Cekic C and Ozgen M. Comparison of antioxidant capacity and phytochemical properties of wild and cultivated red raspberries (Rubus idaeus L.). Journal of Food Composition and Analysis, Volume 23, Issue 6, September 2010, Pages 540-544.
15. Goto T, Teraminami A, Lee JY et al. Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese""“diabetic mice. The Journal of Nutritional Biochemistry, Volume 23, Issue 7, July 2012, Pages 768-776.
16. Haffner K, Rosenfeld HJ, Skrede G et al. Quality of red raspberry Rubus idaeus L. cultivars after storage in controlled and normal atmospheres. Postharvest Biology and Technology, Volume 24, Issue 3, April 2002, Pages 279-289.
17. Jeong JB and Jeong HJ. Rheosmin, a naturally occurring phenolic compound inhibits LPS-induced iNOS and COX-2 expression in RAW264.7 cells by blocking NF-kappa B activation pathway. Food and Chemical Toxicology, Volume 48, Issues 8""“9, August""“September 2010, Pages 2148-2153.
18. Jeong JH, Jung J, Lee SR et al. Anti-oxidant, anti-proliferative and anti-inflammatory activities of the extracts from black raspberry fruits and wine. Food Chemistry, Volume 123, Issue 2, 15 November 2010, Pages 338-344.
19. Jin P, Wang SY, Gao H et al. Effect of cultural system and essential oil treatment on antioxidant capacity in raspberries. Food Chemistry, Volume 132, Issue 1, 1 May 2012, Pages 399-405.
20. McDougall GJ, Kulkarnni NN and Stewart D. Berry polyphenols inhibit pancreatic lipase activity in vitro. Food Chemistry, Volume 115, Issue 1, 1 July 2009, Pages 193-199.
21. Miromoto C, Satoh Y, Hara M et al. Anti-obese action of raspberry ketone. Life Sciences, Volume 77, Issue 2, 27 May 2005, Pages 194-204.
22. Ochoa MR, Kesseler AG, Vullioud MB et al. Physical and Chemical Characteristics of Raspberry Pulp: Storage Effect on Composition and Color. LWT - Food Science and Technology, Volume 32, Issue 3, May 1999, Pages 149-153.
23. Park KS. Raspberry ketone increases both lipolysis and fatty acid oxidation in 3T3-L1 adipocytes. Planta Med. 2010 Oct;76(15):1654-8. Epub 2010 Apr 27.
24. Piljac-Zegarac J and Samec D. Antioxidant stability of small fruits in postharvest storage at room and refrigerator temperatures. Food Research International, Volume 44, Issue 1, January 2011, Pages 345-350.
25. Ravoori S, Vadhanam MV, Aqil F et al. Inhibition of estrogen-mediated mammary tumorigenesis by blueberry and black raspberry. J Agric Food Chem. 2012 Jun 6;60(22):5547-55. Epub 2012 May 22.
26. Rosillo MA, Sanchez-Hildago M, Cardeno A et al. Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn's disease. Biochemical Pharmacology, Volume 82, Issue 7, 1 October 2011, Pages 737-745
27. Ross HA, McDougall GJ and Stewart D. Antiproliferative activity is predominantly associated with ellagitannins in raspberry extracts. Phytochemistry, Volume 68, Issue 2, January 2007, Pages 218-228.
28. Stober GD, Wang LS, Zikri N et al. Cancer prevention with freeze-dried berries and berry components. Seminars in Cancer Biology, Volume 17, Issue 5, October 2007, Pages 403-410.
29. U.S. Department of Agriculture, Economic Research Service (USDA/ERS). (2011). Fruit situation and outlook yearbook, October 2011.
30. U.S. Department of Agriculture, Economic Research Service (USDA/ERS). (2011). Vegetables and melons yearbook data, May 2011.
31. Wang SY, Chen CT and Want CY. The influence of light and maturity on fruit quality and flavonoid content of red raspberries. Food Chemistry, Volume 112, Issue 3, 1 February 2009, Pages 676-684.
32. Wu X, Beecher GR, Holden JM et al. Concentrations of Anthocyanins in Common Foods in the United States and Estimation of Normal Consumption. J Agric Food Chem. 2006 May 31;54(11):4069-4075. 2006.
33. Zhang L, Li J, Hogan S et al. Inhibitory effect of raspberries on starch digestive enzyme and their antioxidant properties and phenolic composition. Food Chemistry, Volume 119, Issue 2, 15 March 2010, Pages 592-599.
34. Zhang Z, Knobloch TJ, Seamon LG et al. A black raspberry extract inhibits proliferation and regulates apoptosis in cervical cancer cells. Gynecologic Oncology, Volume 123, Issue 2, November 2011, Pages 401-406.

35. http://www.ars.usda.gov/main/site_main.htm?modecode=80-40-05-25

Milk Thistle Seed

milk thistle.png

1. Davis-Searles PR, Nakanishi Y, Kim NC, et al. Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells. Cancer Res. 2005 May 15;65(10):4448-57.
2. Gallardo-Williams MT, Maronpot RR, Wine RN, Brunssen SH, Chapin RE. Inhibition of the enzymatic activity of prostate-specific antigen by boric acid and 3-nitrophenyl boronic acid. Prostate. 2003 Jan 1;54(1):44-9.
3. Cohen P, Graves HC, Peehl DM, et al. Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma. J Clin Endocrinol Metab. 1992 Oct;75(4):1046-53.
4. Cohen P, Peehl DM, Graves HC, Rosenfeld RG. Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease. J Endocrinol. 1994 Sep;142(3):407-15.
5. Wang P, Cong R, Wang J, Zhang L. Determination of the active flavonoids in silymarine. Se Pu. 1998 Nov;16(6):510-2.
6. Zi X, Agarwal R. Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: implications for prostate cancer intervention. Proc Natl Acad Sci USA. 1999 Jun 22;96(13):7490-5.
7. Lahiri-Chatterjee M, Katiyar SK, Mohan RR, Agarwal R. A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model. Cancer Res. 1999 Feb 1;59(3):622-32.
8. Katiyar SK, Korman NJ, Mukhtar H, Agarwal R. Protective effects of silymarin against photocarcinogenesis in a mouse skin model. J Natl Cancer Inst. 1997 Apr 16;89(8):556-66.
9. Singh RP, Agarwal R. Prostate cancer prevention by silibinin. Curr Cancer Drug Targets. 2004 Feb;4(1):1-11.
10. Available at: http://www.nci.nih.gov/cancertopics/pdq/cam/milkthistle/HealthProfessional/page2. Accessed August 24, 2005.
11. Lee DY, Liu Y. Molecular structure and stereochemistry of silybin A, silybin B, isosilybin A, and isosilybin B, Isolated from Silybum marianum (milk thistle). J Nat Prod. 2003 Sep;66(9):1171-4.
12. Zi X, Feyes DK, Agarwal R. Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells MDA-MB 468: induction of G1 arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of cyclin-dependent kinases and associated cyclins. Clin Cancer Res. 1998 Apr;4(4):1055-64.
13. Tyagi AK, Agarwal C, Chan DC, Agarwal R. Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells. Oncol Rep. 2004 Feb;11(2):493-9.
14. Singh RP, Agarwal R. A cancer chemopreventive agent silibinin, targets mitogenic and survival signaling in prostate cancer. Mutat Res. 2004 Nov 2;555(1-2):21-32.
15. Singh RP, Sharma G, Dhanalakshmi S, Agarwal C, Agarwal R. Suppression of advanced human prostate tumor growth in athymic mice by silibinin feeding is associated with reduced cell proliferation, increased apopotosis, and inhibition of angiogenesis. Cancer Epidemiol Biomarkers Prev. 2003 Sept;12(9):933-9.
16. Anon. Silybum marianum (milk thistle). Altern Med Rev. 1999 Aug;4(4):272-4.
17. Laekeman G, De Coster S, De Meyer K. St. Mary's Thistle: an overview. J Pharm Belg. 2003;58(1):28-31.
18. Wingo PA, Landis S, Ries LA. An adjustment to the 1997 estimate for new prostate cancer cases. CA Cancer J Clin. 1997 Jul;47(4):239-42.
19. Luper S. A review of plants used in the treatment of liver disease: part 1. Altern Med Rev. 1998 Dec;3(6):410-21.
20. Mallikarjuna G, Dhanalakshmi S, Singh RP, Agarwal C, Agarwal R. Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling. Cancer Res. 2004 Sep 1;64(17):6349-56.
21. Altorjay I et al. The effect of silibinin on the free radical scavenger mechanisms of human erythrocytes in vitro. Acta Physiol Hung 1992;80:375-80.
22. Bialecka M. The effect of bioflavonoids and lecithin on the course of experimental atherosclerosis in rabbits. Ann Acad Med Stetin 1997;43:41-56.
23. Bindoli A et al. Inhibitory action of silymarin on lipid peroxide formation in rat liver mitochondria and microsomes. Biochem Pharmacol 1977;26:2405-9.
24. Boigk G et al. Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats. Hepatology 1997;26:643-9.
25. Bokemeyer C et al. Silibinin protects against cisplatin-induced nephrotoxicity without compromising cisplatin or ifosfamide anti-tumor activity. Br J Cancer 1996;74:2036-41.
26. Chen H et al. Protective effects of silibinin and tetrandrine on the outcome of spontaneously hypertensive rats subjected to acute coronary artery occlusion. Int J Cardiol 1993;41:103-8.
27. Dehmlow C et al. Scavenging of reactive oxygen species and inhibition of arachidonic acid metabolism by silibinin in human cells. Life Sci 1996;58:1591- 1600.
28. Dehmlow C et al. Inhibition of Kupffer cell functions as an explanation for the hepatoprotective properties of silibinin. Hepatology 1996;23:749-54.
29. Feher J et al. Effect of silibinin on the activity and expression of superoxide dismutase in lymphocytes from patients with chronic alcoholic liver disease. Free Rad Res Commun 1987;3:373-7.
30. Feher J et al. Liver cell protection in toxic liver lesions. Acta Physiol Hung 1989;73:285-91.
31. Feher J et al. Liver-protective action of silymarin therapy in chronic alcoholic liver disease. Orv Hetil 1989;130:2723-7.
32. Ferenci P et al. Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. J Hepatol 1989;9:105-13.
33. Fuchs E et al. Effects of silibinin and of a synthetic analogue on isolated rat heptatic stellate cells and myofibroblasts. Drug Res 1997;47:1383-7.
34. Geller LI et al. Treatment of fatty hepatosis in diabetics. Probl Endokrinol (Mosk) 1993;39:20-2.
35. Germani E et al. Progressive and selective changes in neurotrophic factor expression and substance P axonal transport induced by perinatal diabetes: protection action of antioxidant treatment. J Neurosci Res 1999;57:521-8.
36. Gershbein LL. Action of dietary trypsin, pressed coffee oil, silymarin, and iron salt on 1,2-dimethylhydrazine tumorigenesis by gavage. Anticancer Res 1994;14:1113-6.
37. Gower JD et al. Prevention by antioxidants of oxidative damage to rabbit kidneys subjected to cold ischemia. Biochem Pharmacol 1989;38:213-15.
38. Kim DH et al. Silymarin and its components are inhibitors of beta-glucuronidase. Biol Pharm Bull 1994;17:443-5.
39. Kreeman V et al. Silymarin inhibits the development of diet-induced hypercholesterolemia in rats. Planta Med 1998;64:138-40.
40. Lahiri-Chatterjee M et al. A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model. Cancer Res 1999;59:622-32.
41. Locher R et al. Inhibitory action of silibinin on low density lipoprotein oxidation. Drug Res 1998;48:236-9.
42. Manna SK et al. Silymarin suppresses TNF-induced activation of NF-kappaB, c-Jun N-terminal kinase, and apoptosis. J Immunol 1999;163:6800-9.
43. Mira L et al. Scavenging of reactive oxygen species by silibinin dehemisuccinate. Biochem Pharmacol 1994;48:753-9.
44. Mowrey D. Guaranteed Potency Herbs: Next Generation Herbal Medicine. Keats Publishing, 1990.
45. Onat D et al. Effect of alpha-tocopherol and silibinin dihemisuccinate on the proliferation of human skin fibroblasts. Biotechnol Appl Biochem 1999;29:213-15.
46. Pietroangelo A et al. Antioxidant activity of silibinin in vivo during long-term iron overload in rats. Gastroenterology 1995;109:1941-9.
47. Rui YC et al. Effects of silibinin on production of oxygen free radical, lipoperoxide and leukotrienes in brain following ischemia and reperfusion. Chung Kuo 1990;11:418-21.
48. Saliou C et al. Selective inhibition of NF-kappaB activation by the flavonoid hepatoprotector silymarin in HepG2. Evidence for different activating pathways. FEBS Lett 1998;440:8-12.
49. Sanhuenza J et al. Changes in the xanthine dehydrogenase/xanthine oxidase ratio in the rat kidney subjected to ischemia-reperfusion stress: preventive effect of some flavonoids. Res Commun Chem Pathol Pharmacol 1992;78:211-8.
50. Scambia G et al. Antiproliferative effect of silibinin on gynecological malignancies: synergism with cisplatin and doxorubicin. European J Cancer 1996;32A:877-82.
51. Schonfeld J et al. Silibinin, a plant extract with antioxidant and membrane stabilizing properties, protects exocrine pancreas from cyclosporin A toxicity. CMLS Cell Mol Life Sci 1997; 53:917-20.
52. Schriewer H, Rauen HM. The effect of silibinin dihemisuccinate on cholesterol biosynthesis in rat liver homogenates. Arzneimittelforschung 1977;27:1691-4.
53. Skottova N, Krecman V. Silymarin as a potential hypocholesterolemic drug. Physiol Res 1998;47:1-7.
54. Skottova N, Krecman V. Dietary silymarin improves removal of low density lipoproteins by the perfused rat liver. Acta Univ Palacki Fac Med 1998;141:39-40.
55. Skottova N et al. Activities of silymarin and its flavolignans upon low density lipoprotein oxidizability in vitro. Phytother Res 1999; 13:535-7.
56. Sonnenbichler J et al. Biochemical effects of the flavonolignan silibinin on RNA, protein, and DNA synthesis in rat livers. Progress Clin Biol Res 1986;213:319-31.
57. Sonnenbichler J et al. Stimulatory effects of silibinin and silichristin from the milk thistle Silybum marianum on kidney cells. J Pharmacol Exp Ther 1999;290:1375-83.
58. Strauber RE, Stindl G. Protective effect of silibinin against ethanol-induced cytotoxicity in HepG2 cells. J Hepatol 1999;30 (Suppl):277.
59. Soto CP et al. Prevention of alloxan-induced diabetes in the rat by silymarin. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 1998;119:125-9.
60. Tang ZJ. Alterations in insulin receptor in injured rats and the effects of dexamethasone and silibinin. Chung Hua 1991;7:214-7.
61. Valenzuela A et al. Selectivity of silymarin on the increase of glutathione content in different tissues of the rat. Planta Med 1989;55:420-2.
62. Valenzuela A et al. Effect of silibinin dihemisuccinate on the ethanol metabolizing systems of the rat liver. Cell Biochem Funct 1989;7:173-8.
63. Valenzuela A, Garrido A. Biochemical bases of the pharmacological action of the flavonoid silymarin and its structural isomer silibinin. Biol Res 1994;27:105-12.
64. Velussi M et al. Long-term (12 months) treatment with antioxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde in cirrhotic diabetic patients. J Hepatol 1997;26:871-9.
65. Zhao J, Agarwal R. Tissue distribution of silibinin, the major active constituent of silymarin, in mice and its association with enhancement of phase II enzymes: implications in cancer chemoprevention. Carcinogenesis 1999;20:2101-8.
66. Zhao J et al. Significant inhibition by the flavonoid antioxidant silymarin against 12_Otetradecanoylphorbol 13-acetate-caused modulation of antioxidant and inflammatory enzymes, and coclooxygenase 2 and interleukin-1 alpha expression in SENCAR mouse epidermis: implications in the prevention of stage I tumor promotion. Mol Carcinog 1999;26:321-33.
67. Zi X et al. Novel cancer chemopreventive effects of silymarin: inhibition of mRNA expression of an endogenous tumor promoter TNF alpha. Biochem Biophys Res Commun 1997;239:334-9.
68. Zi X et al. Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells MDA-MB 468; induction of G1 arrest through an increase in Cip1/p21concommitant with a decrease in kinase activity of cyclin-dependent kinases and associated cyclins. Clin Cancer Res 1998;4:1055-64.
69. Zi X, Agarwal R. Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: implications for prostate cancer intervention. Proc Natl Acad Sci USA 1999;96:7490-5.
70. Campos, R., A. Garrido, R. Guerra, A. Valenzuela. 1989. Silybin dihemisuccinate protects against glutathione depletion and lipid peroxidation induced by acetaminophen on rat liver. Planta Med 55(5):417"“419
71. Hikino, H., Y. Kiso, H. Wagner, M. Fiebig. 1984. Antihepatotoxic actions of flavonolignans from Silybum marianum fruits. Planta Med 50(3):248"“250
72. Kiesewetter, E., I. Leodolter, H. Thaler. 1977. [Results of two double-blind studies on the effect of silymarin in chronic hepatitis] [In German]. Leber Magen Darm 7(5):318"“323
73. Krecman, V., N. Skottova, D. Walterova, J. Ulrichova, V. Simanek. 1998. Silymarin inhibits the development of diet-induced hypercholesterolemia in rats. Planta Med 64(2):138"“142
74. Mourelle, M., P. Muriel, L. Favari, T. Franco. 1989. Prevention of CC14-induced liver cirrhosis by silymarin. Fundam Clin Pharm 3(3):183"“191
75. Plomteux, G. et al. 1977. Hepatoprotector action of silymarin in human acute viral hepatitis. Int Res Commun Syst 5
76. Skottova, N. and V. Krecman. 1998. Silymarin as a potential hypocholesterolaemic drug. Physiol Res 47(1):1"“7
77. Bratman, Steve, Dr. Complementary & Alternative Health: The Scientific Verdict on What Really Works. London, UK: Collins, 2007. Print. 94. Gaby, Alan R., MD. The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions. 3rd ed. New York, NY: Three Rivers Press, 2006. Print.

78. Murray, Michael, ND. The Pill Book Guide to Natural Medicines: Vitamins, Minerals, Nutritional Supplements, Herbs, And Other Natural Products. New York, NY: Bantam Books, 2002. Print.

Cardamom

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1.Verma SK, "Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum)," Indian J Biochem Biophys, Dec, 2009, avaliable from https://www.ncbi.nlm.nih.gov/pubmed/20361714, Accessed January 16, 2018.

2. Souissi M, Axelmat J, Kamel C, Antibacterial and Ant-iinflammatory activities of Cardamom (Elettaria cardamomum) extracts: potential therapeutic benefits for peridontal infections. Anaerobe 2020 Vol 61

3. S.T. Auti, Y.A. Kulkarni. Neuroprotective effect of cardamom oil against aluminum induced neurotoxicity in rats Frontiers in Neurology, 10 (2019), p. 399

4. A.A. Gomaa, R.M. Makboul, M.A. El-Mokhtar, E.A. Abdel-Rahman, I.A. Ahmed, M.A. Nicola. Terpenoid-rich Elettaria cardamomum extract prevents Alzheimer-like alterations induced in diabetic rats via inhibition of GSK3β activity, oxidative stress and pro-inflammatory cytokines. Cytokine, 113 (2019), pp. 405-416

5. S.S. Husain, M. Ali. Analysis of volatile oil of the fruits of Elettaria cardamomum (L.) Maton and its antimicrobial activity. World Journal of Pharmacy and Pharmaceutical Sciences, 3 (2) (2014), pp. 1798-1808

6. V.S. Korikanthimathm, D. Prasath, G. Rao. Medicinal properties of cardamom Elettaria cardamomum. Journal of Medicinal and Aromatic Plant Sciences, 22 (2000), pp. 683-685

7. O. Mirmosayyeb, A. Tanhaei, H.R. Sohrabi, R.N. Martins, M. Tanhaei, M.A. Najafi, R. Meamar. Possible role of common spices as a preventive and therapeutic agent for Alzheimer's disease. International Journal of Preventive Medicine, 8 (2017)p. 5

8. H. Okugawa, M. Moriyasu, S. Matsushita, K. Saiki, Y. Hashimoto, K. Matsumoto, A. Kato. Evaluation of crude drugs by a combination of enfleurage and chromatography-4-on flavor components in seeds of Amomum cardamomum and Elettaria cardamomum. Shoyakugaku Zasshi, 42 (1) (1988), pp. 94-97

9. K.P.A. Padmakumari Amma, P.N. Venugopalan Nair, I. Sasidharan, M. Priya Rani. Chemical composition, flavonoid-phenolic contents and radical scavenging activity of four major varieties of cardamom. International Journal of Biological & Medical Research, 3 (2010), pp. 20-24

10. S. Sengottuvelu. Cardamom (Elettaria cardamomum Linn. Maton) seeds in health. Nuts and seeds in health and disease prevention, Academic Press (2011), pp. 285-291

11. Muthusamy M, Dhanya M.K, Warkentin T.D, Botany, traditional uses, phytochemistry and biological activities of cardamom [Elettaria cardamomum (L.) Maton] – A critical review. Journal of Ethnopharmacology. Volume 246, 10 January 2020

12. Masoumi-Ardakani Y, Mahmoudvand H, Amin M, Esmaeilpour K, Ghazvini H, Khalifeh S, Seperhri G. The effect of Elettaria cardamomum extract on anxiety-like behavior in a rat model of post-traumatic stress disorder. Biomedicine & Pharmacotherapy. Volume 87, March 2017, Pages 489-495

13. Makboul RM, El-Mokhtar Mohamed A., Abdel-Rahman E.a., Ahmed Israa A., Nicola MA.. Terpenoid-rich Elettaria cardamomum extract prevents Alzheimer-like alterations induced in diabetic rats via inhibition of GSK3ß activity, oxidative stress and pro-inflammatory cytokines. Cytokine Vol 113, Jan 2019, 405-416

14. Malti JE, Mountassif D, Amarouch H. Antimicrobial activity of Elettaria cardamomum: Toxicity, biochemical and histological studies. Food Chemistry Vol 104, 4 2007 1560-1568

15. Jamal A, Kalim J, Aslam M, Jafri M.A. Gastroprotective effect of cardamom, Elettaria cardamomum fruits in rats. Journal of Ethnopharmacology Vol 103, 2, Jan 2006, 149-153

16. Elguindy NM, Galila Y.A, El Azab EF, Maghraby HK. Chemoprotective Effect of Elettaria Cardamomum against Chemically induced Hepatocellular Carcinoma in Rats by inhibiting NF-kB, Oxidative Stress, and Activity of Ornithine Decarboxylase. South African Journal of Botany, Vol 105, Jul 2016, 251-258

17. Zahedi SG, Qorbani M, Esfahani-Nasli E, Aghasi M, Khoshamal H, Keshavarz A, Sotoudeh G. The effects of Elettaria cardamom supplementation on inflammatory markers and vascular function in patients with type 2 diabetes mellitus: A mechanism-based randomized clinical trial. Journal of Herbal Medicine. Vol 25, Feb 2021.

18. Anwaruul HG, Jabeen Q, Khan Au, Abdul JS. Gutmodulatory, blood pressure lowering, diuretic and sedative activities of cardamom. Journal of Ethnopharmacology Vol 115, 3. 2008. 4663-472

19. Bouzabata A, Mahomoodally MF. A quantitative documentation of traditionally-used medicinal plants from Northeastern Algeria: Interactions of beliefs among healers and diabetic patients. Journal of Herbal Medicine, vol 22, Aug 2020. Bhide, Monica.

20. Bhattacharjee S, et al. Inhibition of Lipid Peroxidation and Enhancement of GST Activity by Cardamom and Cinnamom during Chemically induced Colon Carcinogenesis in Swiss albino mice. Asia Pacific Journal of Cancer Prevention, 2007, Vol 8. 4. 578-582.

21."Queen of Spices", Saveur, 8 March 2010. Retrieved on 4 December 2014.

Acai Berry

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  1. Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci USA. 1993 Sep 1;90(17):7915-22.

  2. Poon HF, Calabrese V, Scapagnini G, Butterfield DA. Free radicals and brain aging. Clin Geriatr Med. 2004 May;20(2):329-59.

  3. Zikri NN, Riedl KM, Wang LS, Lechner J, Schwartz SJ, Stoner GD. Black raspberry components inhibit proliferation, induce apoptosis, and modulate gene expression in rat esophageal epithelial cells. Nutr Cancer. 2009 Nov 6;61(6):816-26.

  4. Shin DY, Lee WS, Lu JN, et al. Induction of apoptosis in human colon cancer HCT-116 cells by anthocyanins through suppression of Akt and activation of p38-MAPK. Int J Oncol. 2009 Dec;35(6):1499-504.

  5. Shin DY, Ryu CH, Lee WS, et al. Induction of apoptosis and inhibition of invasion in human hepatoma cells by anthocyanins from meoru. Ann N Y Acad Sci. 2009 Aug;1171:137-48.

  6. Li L, Adams LS, Chen S, Killian S, Ahmed A, Seeram AP. Eugenia jambolana Lam. berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells. J Agric Food Chem. 2009 Feb 11;57(3):826-31.

  7. Xia M, Ling W, Zhu H, et al. Anthocyanin attenuates CD40-mediated endothelial cell activation and apoptosis by inhibiting CD40-induced MAPK activation. Atherosclerosis. 2009 Jan;202(1):41-7.

  8. Toufektsian MC, de Lorgeril M, Nagy N, et al. Chronic dietary intake of plant-derived anthocyanins protects the rat heart against ischemia-reperfusion injury. J Nutr. 2008 Apr;138(4):747-52.

  9. Lehtonen HM, Suomela JP, Tahvonen R, et al. Berry meals and risk factors associated with metabolic syndrome. Eur J Clin Nutr. 2010 Mar 3.

  10. Torronen R, Sarkkinen E, Tapola N, Hautaniemi E, Kilpi K, Niskanen L. Berries modify the postprandial plasma glucose response to sucrose in healthy subjects. Br J Nutr. 2009 Nov 24:1-4.

  11. Jurgonski A, Juskiewicz J, Zdunczyk Z. Ingestion of black chokeberry fruit extract leads to intestinal and systemic changes in a rat model of prediabetes and hyperlipidemia. Plant Foods Hum Nutr. 2008 Dec;63(4):176-82.

  12. Mertens-Talcott SU, Rios J, Jilma-Stohlawetz P, et al. Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers. J Agric Food Chem. 2008;56:7796-802.

  13. Schauss AG, Wu X, Prior RL, Ou B, Huang D, Owens J, Agarwal A, Jensen GS, Hart AN, Shanbrom E. Antioxidant capacity and other bioactivities of the freeze-dried Amazonian palm berry, Euterpe oleraceae mart. (acai). J Agric Food Chem. 2006 Nov 1;54(22):8604-10.

  14. Schauss AG, Wu X, Prior RL, Ou B, Huang D, Owens J, Agarwal A, Jensen GS, Hart AN, Shanbrom E. Antioxidant capacity and other bioactivities of the freeze-dried Amazonian palm berry, Euterpe oleraceae mart. (acai). J Agric Food Chem. 2006 Nov 1;54(22):8604-10.

  15. Cao G, Verdon CP, Wu AH, Wang H, Prior RL. Automated assay of oxygen radical absorbance capacity with the COBAS FARA II. Clin Chem. 1995 Dec;41(12 Pt 1):1738-44.

  16. Ou B, Hampsch-Woodill M, Prior RL. Development and validation of an improved oxygen radical absorbance capacity assay using fluorescein as the fluorescent probe. J Agric Food Chem. 2001 Oct;49(10):4619-26.

  17. Available at: ars.usda.gov/is/AR/archive/feb99/aging0299.pdf. Accessed March 3, 2010.

  18. Cao G, Verdon CP, Wu AH, Wang H, Prior RL. Automated assay of oxygen radical absorbance capacity with the COBAS FARA II. Clin Chem. 1995 Dec;41(12 Pt 1):1738-44.

  19. Ou B, Hampsch-Woodill M, Prior RL. Development and validation of an improved oxygen radical absorbance capacity assay using fluorescein as the fluorescent probe. J Agric Food Chem. 2001 Oct;49(10):4619-26.

  20. Davalos A, Gomez-Cordoves C, and Bartoloma B. Extending applicability of the oxygen radical absorbance capacity (ORAC Fluorescein) assay. J Agric Food Chem. 2004; 52:48-54.

  21. Mertens-Talcott SU, Rios J, Jilma-Stohlawetz P, et al. Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers. J Agric Food Chem. 2008;56:7796-802.

  22. Cao G, Verdon CP, Wu AH, Wang H, Prior RL. Automated assay of oxygen radical absorbance capacity with the COBAS FARA II. Clin Chem. 1995 Dec;41(12 Pt 1):1738-44.

  23. Xu BJ, Yuan SH, Chang SK. Comparative analyses of phenolic composition, antioxidant capacity, and color of cool season legumes and other selected food legumes. J Food Sci. 2007 Mar;72(2):S167-77.

  24. Cao G, Booth SL, Sadowski JA, Prior RL. Increases in human plasma antioxidant capacity after consumption of controlled diets high in fruit and vegetables. Am J Clin Nutr. 1998 Nov;68(5):1081-7.

  25. Cao G, Russell RM, Lischner N, Prior RL. Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women. J Nutr. 1998 Dec;128(12):2383-90.

  26. Prior RL, Joseph JA, Cao G, Shukitt-Hale B. Can foods forestall aging? Agricult Res. 1999 Feb;47(2):14-17.

  27. Young G, Lawrence R, Schreuder M. Discovery of the Ultimate Superfood. Canandaigua, NY:Life Sciences Press; 2005:48.

  28. Roy S, Khanna S, Alessio HM, et al. Anti-angiogenic property of edible berries. Free Radic Res. 2002 Sep;36(9):1023-31.

  29. Moyer RA, Hummer KE, Finn CE, Frei B, Wrolstad RE. Anthocyanins, phenolics, and antioxidant capacity in diverse small fruits: vaccinium, rubus, and ribes. J Agric Food Chem. 2002 Jan 30;50(3):519-25.

  30. Marcason W. What is the acai berry and are there health benefits?J Am Diet Assoc. 2009 Nov;109(11):1968.

  31. Schauss AG, Wu X, Prior RL, et al. Phytochemical and nutrient composition of the freeze-dried Amazonian palm berry, Euterpe oleracea Mart. (Acai). J Agric Food Chem. 2006 Nov 1;54(22):8598-603.

  32. Schauss AG, Wu X, Prior RL, Ou B, Huang D, Owens J, Agarwal A, Jensen GS, Hart AN, Shanbrom E. Antioxidant capacity and other bioactivities of the freeze-dried Amazonian palm berry, Euterpe oleraceae mart. (acai). J Agric Food Chem. 2006 Nov 1;54(22):8604-10.

  33. Young G, Lawrence R, Schreuder M. Discovery of the Ultimate Superfood. Canandaigua, NY:Life Sciences Press; 2005:48.

  34. Schauss AG, Wu X, Prior RL, Ou B, Huang D, Owens J, Agarwal A, Jensen GS, Hart AN, Shanbrom E. Antioxidant capacity and other bioactivities of the freeze-dried Amazonian palm berry, Euterpe oleraceae mart. (acai). J Agric Food Chem. 2006 Nov 1;54(22):8604-10.

  35. Lichtenthaler R, Belandrino Rodrigues R, Guilherme S. Maia J et al. Total oxidant scavenging capacities of Euterpe oleracea Mart. (Acai) fruits. Int J of Food Sci and Nut. 2005;56:53-64.

  36. Schauss AG, Wu X, Prior RL, Ou B, Huang D, Owens J, Agarwal A, Jensen GS, Hart AN, Shanbrom E. Antioxidant capacity and other bioactivities of the freeze-dried Amazonian palm berry, Euterpe oleraceae mart. (acai). J Agric Food Chem. 2006 Nov 1;54(22):8604-10.

  37. Lichtenthaler R, Belandrino Rodrigues R, Guilherme S. Maia J et al. Total oxidant scavenging capacities of Euterpe oleracea Mart. (Acai) fruits. Int J of Food Sci and Nut. 2005;56:53-64.

  38. Mertens-Talcott SU, Rios J, Jilma-Stohlawetz P, et al. Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers. J Agric Food Chem. 2008;56:7796-802.

  39. Sun X, Seeberger J, Alberico T, et al. Acai palm fruit (Euterpe oleracera Mart.) pulp improves survival of flies on a high fat diet. Exp Gerontol. 2010 Mar;45(3):243-51.

  40. Schauss AG, Wu X, Prior RL, Ou B, Huang D, Owens J, Agarwal A, Jensen GS, Hart AN, Shanbrom E. Antioxidant capacity and other bioactivities of the freeze-dried Amazonian palm berry, Euterpe oleraceae mart. (acai). J Agric Food Chem. 2006 Nov 1;54(22):8604-10.

  41. Sun X, Seeberger J, Alberico T, et al. Acai palm fruit (Euterpe oleracera Mart.) pulp improves survival of flies on a high fat diet. Exp Gerontol. 2010 Mar;45(3):243-51.

  42. Pacheco-Palencia LA, Talcott ST, Safe S, Mertens-Talcott S. Absorption and biological activity of phytochemical-rich extracts from acai (Euterpe oleracea Mart.) pulp and oil in vitro. J Agric Food Chem. 2008 May 28;56(10):3593-600.

  43. Del Pozo-Insfran D, Percival SS, Talcott ST. Acai (Euterpe oleracea Mart.) polyphenolics in their glycoside and aglycone forms induce apoptosis of HL-60 leukemia cells. J Agric Food Chem. 2006 Feb 22;54(4):1222-9.

  44. Ribeiro JC, Antunes LM, Aissa AF, et al. Evaluation of the genotoxic and antigenotoxic effects after acute and subacute treatments with acai pulp (Euterpe oleracea Mart.) on mice using the erythrocytes micronucleus test and the comet assay. Mutat Res.2010 Jan;695(1):22-8.

  45. Stoclet JC, Chataigneau T, Ndjaye M, et al. Vascular protection by dietary polyphenols. Eur J Pharmacol. 2004 Oct;500(1):299-313.

  46. Rocha APM, Carvalho LC, Sousa SV, et al. Endothelium-dependent vasodilator effect of Euterpe oleracea Mart. (Acai) extracts in mesenteric vascular bed of the rat. Vasc Pharmacology. 2007 Feb;46(2):97-104.

  47. Oliveira de Souza M, Silva M, Silva ME, de Paula Oliveira R, Pedrosa ML. Diet supplementation with acai (Euterpe oleracea Mart.) pulp improves biomarkers of oxidative stress and the serum lipid profile in rats. Nutrition. 2009 Dec 17.

  48. Spada PD, Dani C, Bortolini GV, Funchai C, Henriques JA, Salvador M. Frozen fruit pulp of Euterpe oleraceae Mart. (Acai) prevents hydrogen peroxide-induced damage in the cerebral cortex, cerebellum, and hippocampus of rats. J Med Food. 2009 Oct;12(5):1084-8.

  49. Zikri NN, Riedl KM, Wang LS, Lechner J, Schwartz SJ, Stoner GD. Black raspberry components inhibit proliferation, induce apoptosis, and modulate gene expression in rat esophageal epithelial cells. Nutr Cancer. 2009 Nov;61(6):816-26.

  50. Shin DY, Lee WS, Lu JN, et al. Induction of apoptosis in human colon cancer HCT-116 cells by anthocyanins through suppression of Akt and activation of p38-MAPK. Int J Oncol. 2009 Dec;35(6):1499-504.

  51. Shin DY, Ryu CH, Lee WS, et al. Induction of apoptosis and inhibition of invasion in human hepatoma cells by anthocyanins from meoru. Ann N Y Acad Sci. 2009 Aug;1171:137-48.

  52. Li L, Adams LS, Chen S, Killian C, Ahmed A, Seeram NP. Eugenia jambolana Lam. berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells. J Agric Food Chem. 2009 Feb 11;57(3):826-31.

  53. Xia M, Ling W, Zhu H, et al. Anthocyanin attenuates CD40-mediated endothelial cell activation and apoptosis by inhibiting CD40-induced MAPK activation. Atherosclerosis. 2009 Jan;202(1):41-7.

  54. Toufektsian MC, de Lorgeril M, Nagy N, et al. Chronic dietary intake of plant-derived anthocyanins protects the rat heart against ischemia-reperfusion injury. J Nutr. 2008 Apr;138(4):747-52.

  55. Mazza GJ. Anthocyanins and heart health. Ann Ist Super Sanita. 2007;43(4):369-74.

  56. Jurgonski A, Juskiewicz J, Zdunczyk Z. Ingestion of black chokeberry fruit extract leads to intestinal and systemic changes in a rat model of prediabetes and hyperlipidemia. Plant Foods Hum Nutr. 2008 Dec;63(4):176-82.

  57. Ghosh D, Konishi T. Anthocyanins and anthocyanin-rich extracts: role in diabetes and eye function. Asia Pac J Clin Nutr. 2007;16(2):200-8.

  58. Ghosh D, Konishi T. Anthocyanins and anthocyanin-rich extracts: role in diabetes and eye function. Asia Pac J Clin Nutr. 2007;16(2):200-8.

  59. Zafra-Stone S, Yasmin T, Bagchi M, Chatterjee A, Vinson JA, Bagchi D. Berry anthocyanins as novel antioxidants in human health and disease prevention. Mol Nutr Food Res. 2007 Jun;51(6):675-83.

  60. Weisel T, Baum M, Eisenbrand G, et al. An anthocyanin/polyphenolic-rich fruit juice reduces oxidative DNA damage and increases glutathione level in healthy probands. Biotechnol J. 2006 Apr;1(4):388-97.

  61. Zafra-Stone S, Yasmin T, Bagchi M, Chatterjee A, Vinson JA, Bagchi D. Berry anthocyanins as novel antioxidants in human health and disease prevention. Mol Nutr Food Res. 2007 Jun;51(6):675-83.

  62. Koli I, Erlund A, Jula J, Marniemi J, Mattila P, Alfthan G. Bioavailability of various polyphenols from a diet containing moderate amounts of berries. J Agric Food Chem. 2010 Jan 14.

  63. Andres-Lacueva C, Shukitt-Hale B, Galli RL, Jauregui O, Lamuela-Raventos RM, Joseph JA. Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory. Nutr Neurosci. 2005 Apr;8(2):111-20.

  64. Ahmet I, Spangler E, Shukitt-Hale B, et al. Blueberry-enriched diet protects rat heart from ischemic damage. PLoS One. 2009 Jun 19;4(6);e5954.

  65. DeFuria J, Bennett G, Strissel KJ, et al. Dietary blueberry attenuates whole-body insulin resistance in high fat mice by reducing adipocyte death and its inflammatory sequelae. J Nutr. 2009 Aug;139(8):1510-6.

  66. Osman N, Adawi D, Ahrne S, Jeppsson B, Molin G. Probiotics and blueberry attenuate the severity of dextran sulfate sodium (DSS)-induced colitis. Dig Dis Sci. 2008 Sep;53(9):2464-74.

  67. Persson IA, Persson K, Andersson RG. Effect of vaccinum myrtillus and its polyphenols on angiotensin-converting enzyme activity in human endothelial cells. J Agric Food Chem. 2009 Jun 10;57(11):4626-9.

  68. Ramirez MR, Izquierdo I, do Carmo Bassols Raseira M, Zuanazzi JA, Barros D, Henriques AT. Effect of lyophilized Vaccinum berries on memory, anxiety, and locomotion in adult rats. Pharmacol Res. 2005 Dec;52(6):457-62.

  69. Nguyen V, Tang J, Oroudjev E, et al. Cytotoxic effects of bilberry extract on MCF7-GFP-tubulin breast cancer cells. J Med Food. 2010 Feb 4.

  70. Takikawa M, Inoue S, Horio F, Tsuda T. Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice. J Nutr. 2010 Mar;140(3):527-33.

  71. Milbury PE, Graf B, Curran-Celentano JM, Blumberg JB. Bilberry (Vaccinium myrtillus) anthocyanins modulate heme oxygenase-1 and glutathione S-transferase-pi expression in ARPE-19 cells. Invest Ophthalmol Vis Sci. 2007 May;48(5):2343-9.

  72. Knox YM, Hayashi K, Suzutani T, et al. Activity of anthocyanins from fruit extract of Ribes nigrum L. against influenza A and B viruses. Acta Virol. 2001;45(4):209-15.

  73. Nakamura Y, Matsumoto H, Todoki K. Endothelium-dependent vasorelaxation induced by black currant concentrate in rat thoracic aorta. Jpn J Pharmacol. 2002 May;89(1):29-35.

  74. Lyall KA, Hurst SM, Cooney J, et al. Short-term blackcurrent extract consumption modulates exercise-induced oxidative stress and lipopolysaccharide stimulated inflammatory responses. Am J Physiol Regul Integr Comp Physiol. 2009 Jul;297(1):R70-81.

  75. Nakaishi H, Matsumoto H, Tominaga S, Hirayama M. Effects of black current anthocyanoside intake on dark adaptation and VDT work-induced transient refractive alteration in healthy humans. Altern Med Rev. 2000 Dec;5(6):553-62.

  76. Cavanagh HM, Hipwell M, Wilkinson JM. Antibacterial activity of berry fruits used for culinary purposes. J Med Food. 2003 Spring;6(1):57-61.

  77. Gupta K, Chou MY, Howell A, Wobbe C, Grady R, Stapleton AE. Cranberry products inhibit adherence of p-fimbriated Escherichia coli to primary cultured bladder and vaginal epithelial cells. J Urol. 2007 Jun;177(6):2357-60.

  78. Valentova K, Stejskal D, Bednar P, et al. Biosafety, antioxidant status and metabolites in urine after consumption of dried cranberry juice in healthy women: a pilot double-blind placebo-controlled trial. J Agric Food Chem. 2007 Apr 18;55:3217-24.

  79. Liu M, Lin LQ, Song BB, et al. Cranberry phytochemical extract inhibits SGC-7901 cell growth and human tumor xenografts in Balb/c nu/nu mice. J Agric Food Chem. 2009 Jan 28;57(2):762-8.

  80. Kresty LA, Howell AB, Baird M. Cranberry proanthocyanidins induce apoptosis and inhibit acid-induced proliferation of human esophageal adenocarcinoma cells. J Agric Food Chem. 2008 Feb 13;56(3):676-80.

  81. Zhang L, Ma J, Pan K, Go VL, Chen J, You WC. Efficacy of cranberry juice on Helicobacter pylori infection: a double-blind, randomized placebo-controlled trial. Helicobacter. 2005 Apr;10(2):139-45.

  82. Burger O, Weiss E, Sharon N, Tabak M, Neeman I, Ofek I. Inhibition of Helicobacter pylori adhesion to human gastric mucus by a high-molecular-weight constituent of cranberry juice. Crit Rev Food Sci Nutr. 2002;42(3 Suppl):279-84.

  83. Roschek B Jr, Fink RC, McMichael MD, Li D, Alberte RS. Elderberry flavonoids bind to and prevent H1N1 infection in vitro. Phytochemistry. 2009 Jul;70(10):1255-61.

  84. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw. 2001 Apr-Jun;12(2):290-6.

Kale

kale.png

1. Ambrosone CB, Tang L. Cruciferous vegetable intake and cancer prevention: role of nutrigenetics. Cancer Prev Res (Phila Pa). 2009 Apr;2(4):298-300. 2009.
2. Angeloni C, Leoncini E, Malaguti M, et al. Modulation of phase II enzymes by sulforaphane: implications for its cardioprotective potential. J Agric Food Chem. 2009 Jun 24;57(12):5615-22. 2009.
3. Banerjee S, Wang Z, Kong D, et al. 3,3'-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer. 3,3'-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer.  2009.
4. Bhattacharya A, Tang L, Li Y, et al. Inhibition of bladder cancer development by allyl isothiocyanate. Carcinogenesis. 2010 Feb;31(2):281-6. 2010.
5. Bryant CS, Kumar S, Chamala S, et al. Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells. Molecular Cancer 2010, 9:47. 2010.
6. Carpenter CL, Yu MC, and London SJ. Dietary isothiocyanates, glutathione S-transferase M1 (GSTM1), and lung cancer risk in African Americans and Caucasians from Los Angeles County, California. Nutr Cancer. 2009;61(4):492-9. 2009.
7. Christopher B, Sanjeez K, Sreedhar C, et al. Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells. Molecular Cancer Year: 2010 Vol: 9 Issue: 1 Pages/record No.: 47. 2010.
8. Clarke JD, Dashwood RH and Ho E. Multi-targeted prevention of cancer by sulforaphane. Cancer Lett. 2008 Oct 8;269(2):291-304. 2008.
9. Clarke JD, Dashwood RH, Ho E. Multi-targeted prevention of cancer by sulforaphane. Cancer Lett. 2008 Oct 8;269(2):291-304. 2008.
10. Cornelis MC, El-Sohemy A, Campos H. GSTT1 genotype modifies the association between cruciferous vegetable intake and the risk of myocardial infarction. Am J Clin Nutr. 2007 Sep;86(3):752-8. 2007.
11. Higdon JV, Delage B, Williams DE, et al. Cruciferous Vegetables and Human Cancer Risk: Epidemiologic Evidence and Mechanistic Basis. Pharmacol Res. 2007 March; 55(3): 224-236. 2007.
12. Ho E, Clarke JD, Dashwood RH. Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention. J Nutr. 2009 Dec;139(12):2393-6. 2009.
13. Hutzen B, Willis W, Jones S, et al. Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells. Cancer Cell International 2009, 9:24. 2009.
14. Jiang H, Shang X, Wu H, et al. Combination treatment with resveratrol and sulforaphane induces apoptosis in human U251 glioma cells. Neurochem Res. 2010 Jan;35(1):152-61. 2010.
15. Kahlon TS, Chiu MC, and Chapman MH. Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage. Nutr Res. 2008 Jun;28(6):351-7. 2008.
16. Konsue N, Ioannides C. Modulation of carcinogen-metabolising cytochromes P450 in human liver by the chemopreventive phytochemical phenethyl isothiocyanate, a constituent of cruciferous vegetables. Toxicology. 2010 Feb 9;268(3):184-90. 2010.
17. Kunimasa K, Kobayashi T, Kaji K et al. Antiangiogenic effects of indole-3-carbinol and 3,3'-diindolylmethane are associated with their differential regulation of ERK1/2 and Akt in tube-forming HUVEC. J Nutr. 2010 Jan;140(1):1-6. 2010.
18. Lakhan SE, Kirchgessner A, Hofer M. Inflammatory mechanisms in ischemic stroke: therapeutic approaches. Journal of Translational Medicine 2009, 7:97. 2009.
19. Larsson SC, Andersson SO, Johansson JE, et al. Fruit and vegetable consumption and risk of bladder cancer: a prospective cohort study. Cancer Epidemiol Biomarkers Prev. 2008 Sep;17(9):2519-22. 2008.
20. Li F, Hullar MAJ, Schwarz Y, et al. Human Gut Bacterial Communities Are Altered by Addition of Cruciferous Vegetables to a Controlled Fruit- and Vegetable-Free Diet. Journal of Nutrition, Vol. 139, No. 9, 1685-1691, September 2009. 2009.
21. Lin J, Kamat A, Gu J, et al. Dietary intake of vegetables and fruits and the modification effects of GSTM1 and NAT2 genotypes on bladder cancer risk. Cancer Epidemiol Biomarkers Prev. 2009 Jul;18(7):2090-7. 2009.
22. Machijima Y, Ishikawa C, Sawada S, et al. Anti-adult T-cell leukemia/lymphoma effects of indole-3-carbinol. Retrovirology 2009, 6:7. 2009.
23. Nakamura Y, Yogosawa S, Izutani Y et al. A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy. Mol Cancer. 2009 Nov 12;8:100. 2009.
24. Navarro SL, Chang JL, Peterson S et al. Modulation of human serum glutathione S-transferase A1/2 concentration by cruciferous vegetables in a controlled feeding study is influenced by GSTM1 and GSTT1 genotypes. Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):2974-8. 2009.
25. Nettleton JA, Steffen LM, Mayer-Davis EJ, et al. Dietary patterns are associated with biochemical markers of inflammation and endothelial activation in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Clin Nutr. 2006 Jun;83(6):1369-79. 2006.
26. Pellegrini N, Chiavaro E, Gardana C et al. Effect of Different Cooking Methods on Color, Phytochemical Concentration, and Antioxidant Capacity of Raw and Frozen Brassica Vegetables. J. Agric. Food Chem., 2010, 58 (7), pp 4310'4321. 2010.
27. Prawan A, Saw CL, Khor TO et al. Anti-NF-kappaB and anti-inflammatory activities of synthetic isothiocyanates: effect of chemical structures and cellular signaling. Chem Biol Interact. 2009 May 15;179(2-3):202-11. 2009.
28. Rungapamestry V, Duncan AJ, Fuller Z et al. Effect of cooking brassica vegetables on the subsequent hydrolysis and metabolic fate of glucosinolates. Proc Nutr Soc. 2007 Feb;66(1):69-81. 2007.
29. Silberstein JL, Parsons JK. Evidence-based principles of bladder cancer and diet. Urology. 2010 Feb;75(2):340-6. 2010.
30. Steinbrecher A, Linseisen J. Dietary Intake of Individual Glucosinolates in Participants of the EPIC-Heidelberg Cohort Study. Ann Nutr Metab 2009;54:87-96. 2009.
31. Tang L, Zirpoli GR, Guru K et al. Consumption of Raw Cruciferous Vegetables is Inversely Associated with Bladder Cancer Risk. Cancer Res. 2007 Apr 15;67(8):3569-73. 2007.
32. Tarozzi A, Morroni F, Merlicco A, et al. Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line. J Neurochem. 2009 Dec;111(5):1161-71. 2009.
33. Thompson CA, Habermann TM, Wang AH, et al. Antioxidant intake from fruits, vegetables and other sources and risk of non-Hodgkin's lymphoma: the Iowa Women's Health Study. Int J Cancer. 2010 Feb 15;126(4):992-1003. 2010.
34. Vivar OI, Saunier EF, Leitman DC et al. Selective activation of estrogen receptor-{beta} target genes by 3,3'-diindolylmethane. Endocrinology. 2010 Apr;151(4):1662-7. 2010.
35. Yang G, Gao YT, Shu XO et al. Isothiocyanate exposure, glutathione S-transferase polymorphisms, and colorectal cancer risk. Am J Clin Nutr. 2010 Mar;91(3):704-11. 2010.
36. Zhang Y. Allyl isothiocyanate as a cancer chemopreventive phytochemical. Mol Nutr Food Res. 2010 Jan;54(1):127-35. 2010.
37. Zhu H, Jia Z, Zhou K et al. Cruciferous dithiolethione-mediated coordinated induction of total cellular and mitochondrial antioxidants and phase 2 enzymes in human primary cardiomyocytes: cytoprotection against oxidative/electr. Exp Biol Med (Maywood). 2009 Apr;234(4):418-29. 2009.
38. Heber D. Vegetables, fruits and phytoestrogens in the prevention of diseases. J Postgrad Med. Apr-Jun 2004;50(2):145-9.
39. Xiao D, Pinto JT, Gundersen GG, Weinstein IB. Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells. Mol Cancer Ther. Sep 2005;4(9):1388-98.
40. Padilla G, Cartea ME, Velasco P, de Haro A, Ordas A. Variation of glucosinolates in vegetable crops of Brassica rapa. Phytochemistry. Feb 2007;68(4):536-45.
41. Hwang ES, Jeffery EH. Induction of quinone reductase by sulforaphane and sulforaphane N-acetylcysteine conjugate in murine hepatoma cells. J Med Food. 2005;8(2):198-203.
42. Wang LI, Giovannucci EL, Hunter D, Neuberg D, Su L, Christiani DC. Dietary intake of Cruciferous vegetables, Glutathione S-transferase (GST) polymorphisms and lung cancer risk in a Caucasian population. Cancer Causes Control. Dec 2004;15(10):977-85.
43. Cornblatt BS, Ye L, Dinkova-Kostova AT, et al. Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast. Carcinogenesis. 2007 Jul;28(7):1485-90.
44. Thejass P, Kuttan G. Augmentation of natural killer cell and antibody-dependent cellular cytotoxicity in BALB/c mice by sulforaphane, a naturally occurring isothiocyanate from broccoli through enhanced production of cytokines IL-2 and IFN-gamma. Immunopharmacol Immunotoxicol. 2006;28(3):443-57.
45. Khor TO, Hu R, Shen G, et al. Pharmacogenomics of cancer chemopreventive isothiocyanate compound sulforaphane in the intestinal polyps of ApcMin/+ mice. Biopharm Drug Dispos. Dec 2006;27(9):407-20.
46. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr. Oct 1999;70(4):509-16.
47. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr. Oct 1999;70(4):517-24.
48. Dwyer JH, Navab M, Dwyer KM, et al. Oxygenated carotenoid lutein and progression of early atherosclerosis: the Los Angeles atherosclerosis study. Circulation. 2001 Jun 19;103(24):2922-7.
49. McAlister V. Control of coagulation: a gift of Canadian agriculture. Clin Invest Med. Dec 2006;29(6):373-7.
50. Schurgers LJ, Teunissen KJ, Hamulyak K, Knapen MH, Vik H, Vermeer C. Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood. Apr 15 2007;109(8):3279-83.
51. Available at: http://www.nutritiondata.com/facts-C00001-01c20dh.html. Accessed November 20, 2007.
52. "World War Two vegetable comes back as 'superfood'". Daily Mail (London). 3 October 2007.
53. Bailey, L. H., (1912, republished in 1975). Jersey kale Photo. In Cyclopedia of American Agriculture: Vol. II--crops. Macmillan Publishing, New York. p. 389-390. ISBN 0-405-06762-3. Google Book Search. Retrieved on Nov, 2012.
54. Ravensthorpe, Michael (7 March 2013). "The Health Benefits of Kale". Spiritfoods. Retrieved 2 July 2013.
55. AA.VV. La cucina tradizionale Lombarda, ed. Newton Compton, A. Molinari L'antica cuciniera ligure, ed. De Ferrari AA
56. "Breeding Better Broccoli: Research Points To Pumped Up Lutein Levels In Broccoli". Science Daily. 8 November 2009. Retrieved 5 September 2010.
57. Yuesheng Zhang & Eileen C. Callaway (May 2002). "High cellular accumulation of sulphoraphane, a dietary anticarcinogen, is followed by rapid transporter-mediated export as a glutathione conjugate". The Biochemical journal 364 (Pt 1): 301"“307. PMC 1222573. PMID 11988104.
58. Warwick Medical School, University of Warwick (15 May 2007). "Research Says Boiling Broccoli Ruins Its Anti Cancer Properties".
59. "Broccoli chemical's cancer check". BBC News. 7 February 2006. Retrieved 5 September 2010.
60. "How Dietary Supplement May Block Cancer Cells". Science Daily. 30 June 2010. Retrieved 5 September 2010.
61. Talwinder Singh Kahlon, Mei-Chen M. Chiu, Mary H. Chapman (2008). "Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage". Nutrition Research 28: 351"“357.
62. Joy Larkcom (1 June 2003). The Organic Salad Garden. frances lincoln ltd. pp. 30"“32. ISBN 978-0-7112-2204-5. Retrieved 30 August 2012.
63. Cuthbertson, David Cuningham (1945). Autumn in Kyle and the Charm of Cunninghame. London: Jenkins. Page 186

64. http://www.ars-grin.gov/duke/

65. http://ndb.nal.usda.gov/ndb/foods

Reishi

reishi.png

1. Willard, T., 1990. The Reishi Mushroom: Herb of Spiritual Potency and Medical Wonder. Sylvan Press.

2. Matsomoto, K., 1979. The Mysterious Reishi Mushroom. Santa Barbara: Woodbridge Press Publishing Company.

3. Carlson, J., 1996. Reishi Mushroom. New Editions Health World, pp: 23-25.

4. Komoda, Y., M. Shimizu and Y. Sonoda, 1989. Ganoderic acid and its derivatives as cholesterol synthesis inhibitors; Chem. Pharm. Bull, 37(2): 531-533.

5. Stamens, P., 2000. Growing Gourmet and Medicinal Mushrooms, 3rd Ed; Ten Speed Press.

6. Zhou, X., J. Lin, Y. Yin, J. Zhao, X. Sun and K. Tang, 2007. Ganodermataceae: natural products and their related pharmacological functions. Am. J. Chin. Med., 35(4): 559-574.

7. Wasser, S.P. and A.L. Weis, 1999. Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective. Crit Rev. Immunol., 19(1): 65-96.

8. Chang, H. M. and P. P. H. But, "Pharmacology and Applications of Chinese Materia Medica, vol. 1 (Singapore: World Scientific Company 1987) 144-146

9. Haak-Frendscho, M., K. Kino, T. Sone et al. "Ling Zhi-8: A Novel T-Cell Mitogen Induces Cytokine Production and Upregulation of ICAM-1 Expression" Cellular Immunology 150(1) 1993; 101-113

10. Hobbs, Christopher and Michael Miovic ed. Medical Mushrooms: AN Exploration of Tradition, Healing and Culture, 2nd ed. (Santa Cruz: Botanical Press) 1995. p.104

11. Kohda, H., W. Tokumoto, K. Sakamoto, et al. "The Biologically Active Constituents of Ganoderma Lucidum (Fr.) Karst. Histamine Release-Inhibitory Triterpenes", Chemical Pharmacy Bulletin 33 (1985) 1367-1374

12. Lei, L and Z. Lin, "Effect of Ganoderma Polysaccharides on the Activity of DNA Polymerase in Spleen Cells Stimulated by Alloantigens in Mice in Vitro" Beijing Yike Daxue Xuebao [Journal of Beijing Medical University] 23 (1991) 329"“333

13. Matsumoto, K-Osai, The Mysterious Reishi Mushroom (Santa Barbara: Woodbridge Press 1979)

14. Toth, J. O., et al., "Les Acides Ganoderques T a Z: Triteroenes Cytotoxique de Ganoderma lucidum (Polyporacee) Thetracedron letters 24 (1983) 1081-1084

15. Kenneth J. REISHI: Ancient herb for modern times. Sylvan Press, 1992.

16. Wasson RG. Divine mushroom of immortality. Harcourt, Brace, Jovanovich, Los Angeles, 80-93, 1968.

17. "Lingzhi". In Pharmacology and Application of Chinese Materia Medica, Vol. I. Chang HM and But RPH, eds. World Scientific: Singapore, 642, 1986.

18. Stanislaus CS. LingzhiMedicine of Kings. New Editions Health World, 38-41, June, 1995.

19. Carlson J. Reishi Mushroom. New Editions Health World, 23-25, April, 1996.

20. Stavinoha WB, et al. Study of the anti-inflammatory activity of Ganoderma lucidum. Presented at the Third Academic/Industry Joint Conference (AIJC), Sapporo, Japan, 1990.

21. Lin JM, Lin CC, Chiu HF, Yang JJ, and Lee SG. Evaluation of the anti-inflammatory and liver protective effects of anoectochilus formosanus ganoderma lucidum and gynostemma pentaphyllum in rats. Am J Chi Med, 1:59-69, 1993. 3215, 1985. 22. Zhang, L. X., H. Mong and X. B. Zhou, "Effect of Japanese Ganoderma Lucidum (GL) Planted in Japan on the Production of Interleukin-2 from Murine Splenocytes", Chung_kuo Chung His I Chieh Ho Tsa Chih [Chinese Journal of Modern Developments in Traditional Medicine] 10(11) 1993; 672-674

23. Kenneth J. REISHI: Ancient herb for modern times. Sylvan Press, 1992.

24. Wasson RG. Divine mushroom of immortality. Harcourt, Brace, Jovanovich, Los Angeles, 80-93, 1968.

25. "Lingzhi". In Pharmacology and Application of Chinese Materia Medica, Vol. I. Chang HM and But RPH, eds. World Scientific: Singapore, 642, 1986.

26. Stanislaus CS. Lingzhi Medicine of Kings. New Editions Health World, 38-41, June, 1995.

27. Carlson J. Reishi Mushroom. New Editions Health World, 23-25, April, 1996.

28. Stavinoha WB, et al. Study of the anti-inflammatory activity of Ganoderma lucidum. Presented at the Third Academic/Industry Joint Conference (AIJC), Sapporo, Japan, 1990.

29. Lin JM, Lin CC, Chiu HF, Yang JJ, and Lee SG. Evaluation of the anti-inflammatory and liver protective effects of anoectochilus formosanus ganoderma lucidum and gynostemma pentaphyllum in rats. Am J Chi Med, 1:59-69, 1993. 3215, 1985. 30. Liu J , Shimizu K , Konishi F , Kumamoto S , Kondo R . The anti-androgen effect of ganoderol B isolated from the fruiting body of Ganoderma lucidum . Bioorg Med Chem. 2007 ; 15 ( 14 ): 4966-4972.

31. Lininger SW, Wright JV, et al, eds. The Natural Pharmacy . Rocklin, CA: Prima Publishing; 1998:303-304.

32. Zhou X , Lin J , Yin Y , Zhao J , Sun X , Tang K . Ganodermataceae: natural products and their related pharmacological functions . Am J Chin Med . 2007 ; 35 ( 4 ): 559-574.

33. Matsumoto K . The Mysterious Reishi Mushroom . Santa Barbara, CA: Woodbridge Press Publishing; 1979.

34. Li EK , Tam LS , Wong CK , et al. Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double-blind, randomized, placebo-controlled pilot trial . Arthritis Rheum . 2007; 57 ( 7 ): 1143-1150.

35. Paterson RR . Ganoderma"”a therapeutic fungal biofactory . Phytochemistry . 2006 ; 67 ( 18 ): 1985-2001.

36. Miyazaki T , Nishijima M . Studies on fungal polysaccharides. XXVII. Structural examination of a water-soluble, antitumor polysaccharide of Ganoderma lucidum . Chem Pharm Bull . 1981 ; 29 ( 12 ): 3611-3616.

37. Kohda H , Tokumoto W , Sakamoto K , et al. The biologically active constituents of Ganoderma lucidum (Fr.) Karst. Histamine release-inhibitory triterpenes . Chem Pharm Bull (Tokyo). 1985 ; 33 ( 4 ): 1367-1374.

38. Zhu M , Chang Q , Wong LK , Chong FS , Li RC . Triterpene antioxidants from Ganoderma lucidum . Phytother Res . 1999 ; 13 ( 6 ): 529-531.

39. Hajjaj H , Macé C , Roberts M , Niederberger P , Fay LB . Effect of 26-oxygenosterols from Ganoderma lucidum and their activity as cholesterol synthesis inhibitors . Appl Environ Microbiol . 2005 ; 71 ( 7 ): 3653-3658.

40. Tang W , Liu JW , Zhao WM , Wei DZ , Zhong JJ . Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells . Life Sci . 2006 ; 80 ( 3 ): 205-211.

41. Mizushina Y , Takahashi N , Hanashima L , et al. Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum . Bioorg Med Chem . 1999 ; 7 ( 9 ): 2047-2052.

42. Cheong J , Jung W , Park W . Characterization of an alkali-extracted peptidoglycan from Korean Ganoderma lucidum . Arch Pharm Res . 1999 ; 22 ( 5 ): 515-519.

43. D'Souza TM , Merritt CS , Reddy CA . Lignin-modifying enzymes of the white rot basidiomycete Ganoderma lucidum . Appl Environ Microbiol . 1999 ; 65 ( 12 ): 5307-5313.

44. Lin ZB , Zhang HN . Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms. Acta Pharmacol Sin . 2004 ; 25 ( 11 ): 1387-1395.

45. Yuen JW , Gohel MD . Anticancer effects of Ganoderma lucidum : a review of scientific evidence . Nutr Cancer . 2005 ; 53 ( 1 ): 11-17.

46. Kuo MC , Weng CY , Ha CL , Wu MJ . Ganoderma lucidum mycelia enhance innate immunity by activating NF-kappaB . J Ethnopharmacol . 2006 ; 103 ( 2 ): 217-222.

47. Müller CI , Kumagai T , O'Kelly J , Seeram NP , Heber D , Koeffler HP . Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells . Leuk Res . 2006 ; 30 ( 7 ): 841-848.

48. Sliva D . Ganoderma lucidum in cancer research . Leuk Res . 2006 ; 30 ( 7 ): 767-768.

49. Kim HS , Kacew S , Lee BM . In vitro chemopreventive effects of plant polysaccharides ( Aloe barbadensis miller , Lentinus edodes , Ganoderma lucidum and Coriolus versicolor ) . Carcinogenesis . 1999 ; 20 ( 8 ): 1637-1640.

50. Gao Y , Gao H , Chan E , et al. Antitumor activity and underlying mechanisms of ganopoly, the refined polysaccharides extracted from Ganoderma lucidum , in mice . Immunol Invest . 2005 ; 34 ( 2 ): 171-198.

51. Pang X , Chen Z , Gao X , et al. Potential of a novel polysaccharide preparation (GLPP) from Anhui-grown Ganoderma lucidum in tumor treatment and immunostimulation . J Food Sci . 2007 ; 72 ( 6 ): S435-S442.

52. Zhu XL , Lin ZB . Effects of Ganoderma lucidum polysaccharides on proliferation and cytotoxicity of cytokine-induced killer cells . Acta Pharmacol Sin . 2005 ; 26 ( 9 ): 1130-1137.

53. Lin YL , Lee SS , Hou SM , Chiang BL . Polysaccharide purified from Ganoderma lucidum induces gene expression changes in human dendritic cells and promotes T helper 1 immune response in BALB/c mice . Mol Pharmacol . 2006 ; 70 ( 2 ): 637-644.

54. Lin YL , Liang YC , Lee SS , Chiang BL . Polysaccharide purified from Ganoderma lucidum induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and p38 mitogen-activated protein kinase pathways . J Leukoc Biol . 2005 ; 78 ( 2 ): 533-543.

55. Li YQ , Wang SF . Anti-hepatitis B activities of ganoderic acid from Ganoderma lucidum . Biotechnol Lett . 2006 ; 28 ( 11 ): 837-841.

56. Lin KI , Kao YY , Kuo HK , et al. Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor Blimp-1 . J Biol Chem . 2006 ; 281 ( 34 ): 24111-24123.

57. Chan WK , Lam DT , Law HK , et al. Ganoderma lucidum mycelium and spore extracts as natural adjuvants for immunotherapy . J Altern Complement Med . 2005 ; 11 ( 6 ): 1047-1057.

58. Lin ZB . Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum . J Pharmacol Sci . 2005 ; 99 ( 2 ): 144-153.

59. Yue GG , Fung KP , Tse GM , Leung PC , Lau CB . Comparative studies of various ganoderma species and their different parts with regard to their antitumor and immunomodulating activities in vitro . J Altern Complement Med . 2006 ; 12 ( 8 ): 777-789.

60. Tang W , Gao Y , Chen G , et al. A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia . J Med Food . 2005 ; 8 ( 1 ): 53-58.

61. Cao QZ , Lin ZB . Ganoderma lucidum polysaccharides peptide inhibits the growth of vascular endothelial cell and the induction of VEGF in human lung cancer cell . Life Sci . 2006 ; 78 ( 13 ): 1457-1463.

62. Stanley G , Harvey K , Slivova V , Jiang J , Sliva D . Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-beta1 from prostate cancercells . Biochem Biophys Res Commun . 2005 ; 330 ( 1 ): 46-52.

63. Kim KC , Kim JS , Son JK , Kim IG . Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells by the Ganoderma lucidum and Duchesnea chrysantha extracts . Cancer Lett . 2007 ; 246 ( 1-2 ): 210-217.

64. Gao Y , Tang W , Dai X , et al. Effects of water-soluble Ganoderma lucidum polysaccharides on the immune functions of patients with advanced lung cancer . J Med Food . 2005 ; 8 ( 2 ): 159-168.

65. Gao Y , Zhou S , Jiang W , Huang M , Dai X . Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients . Immunol Invest . 2003 ; 32 ( 3 ): 201-215.

66. Kim KC , Kim IG . Ganoderma lucidum extract protects DNA from strand breakage caused by hydroxyl radical and UV irradiation . Int J Mol Med . 1999 ; 4 ( 3 ): 273-277.

67. Cheuk W , Chan JK , Nuovo G , Chan MK , Fok M . Regression of gastric large B-Cell lymphoma accompanied by a florid lymphoma-like T-cell reaction: immunomodulatory effect of Ganoderma lucidum (Lingzhi)? Int J Surg Pathol . 2007 ; 15 ( 2 ): 180-186.

68. Morigiwa A , Kitabatake K , Fujimoto Y , Ikekawa N . Angiotensin converting enzyme-inhibitory triterpenes from Ganoderma lucidum . Chem Pharm Bull (Tokyo) . 1986 ; 34 ( 7 ): 3025-3028.

69. Su CY , Shiao MS , Wang CT . Differential effects of ganodermic acid S on the thromboxane A2-signaling pathways in human platelets . Biochem Pharmacol . 1999 ; 58 ( 4 ): 587-595.

70. Wang S , et al. The role of Ganoderma lucidum in immunopotentiation: Effect on cytokine release from human macrophages and T-lymphocytes. In: Program and Abstracts of the 1994 International Symposium on Ganoderm Research . Beijing: Beijing Medical University.

71. Chang H-M, But P, eds. Pharmacology and Applications of Chinese Materia Medica . Vol. 1. Singapore: World Scientific; 1986.

72. Byun S , Rim IH . Studies on the concurrent administration of Ganoderma lucidum extract and glutathione on liver damage induced by carbon tetrachloride in rats . J Pharm . 1987 ; 31 : 133-139.

73. Ho YW , Yeung JS , Chiu PK , et al. Ganoderma lucidum polysaccharide peptide reduced the production of proinflammatory cytokines in activated rheumatoid synovial fibroblast . Mol Cell Biochem . 2007 ; 301 ( 1-2 ): 173-179.

74. Xi Bao Y , Kwok Wong C , Kwok Ming Li E , et al. Immunomodulatory effects of lingzhi and san-miao-san supplementation on patients with rheumatoid arthritis . Immunopharmacol Immunotoxicol . 2006 ; 28 ( 2 ): 197-200.

75. Eo SK , Kim YS , Lee CK , Han SS . Antiherpetic activities of various protein bound polysaccharides isolated from Ganoderma lucidum . J Ethnopharmacol . 1999 ; 68 ( 1-3 ): 175-181.

76. Eo SK , Kim YS , Lee CK , Han SS . Antiviral activities of various water and methanol soluble substances isolated from Ganoderma lucidum . J Ethnopharmacol . 1999 ; 68 ( 1-3 ): 129-136.

77. Wicks SM , Tong R , Wang CZ , et al. Safety and tolerability of Ganoderma lucidum in healthy subjects: a double-blind randomized placebo-controlled trial . Am J Chin Med . 2007 ; 35 ( 3 ): 407-414.

78. http://foodmatters.tv/articles-1/a-magic-mushroom-that-fights-cancer-diabetes

79. Kwok Y , Ng KF , Li CC , Lam CC , Man RY . A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers . Anesth Analg . 2005 ; 101 ( 2 ): 423-426.

80. http://www.mdidea.com/products/new/new03603.html

81. http://www.mskcc.org/cancer-care/herb/reishi-mushroom

82. https://www.ncbi.nlm.nih.gov/pubmed/12372965

83. https://www.ncbi.nlm.nih.gov/pubmed/12596858

84. https://www.ncbi.nlm.nih.gov/pubmed/12916709

85. https://www.ncbi.nlm.nih.gov/pubmed/14630595

Cordyceps

cordyceps.png

1. Holliday, John; Cleaver, Matt; (2008). "Medicinal Value of the Caterpillar Fungi Species of the Genus Cordyceps (Fr.) Link (Ascomycetes). A Review" (PDF). International Journal of Medicinal Mushrooms (New York: Begell House) 10 (3): 219. doi:10.1615/IntJMedMushr.v10.i3.30. ISSN 1521-9437.
2. Winkler, D. 2008a. Yartsa Gunbu (Cordyceps sinensis) and the Fungal Commodification of the Rural Economy in Tibet AR. Economic Botany 63.2: 291"“306
3. Halpern, Georges M. (2007). Healing Mushrooms. Square One Publishers. pp. 65"“86. ISBN 978-0-7570-0196-3.
4. "Neurophilosophy: Brainwashed by a parasite". 2006-11-20. Retrieved 2008-07-02.
5. Hughes, D. P.; Wappler, T.; Labandeira, C. C. (2010). "Ancient death-grip leaf scars reveal ant-fungal parasitism". Biology Letters 7 (1): 67"“70. doi:10.1098/rsbl.2010.0521. PMC 3030878. PMID 20719770. edit
6. Sung, Gi-Ho; Nigel L. Hywel-Jones, Jae-Mo Sung, J. Jennifer Luangsa-ard, Bhushan Shrestha and Joseph W. Spatafora (2007). "Phylogenetic classification of Cordyceps and the clavicipitaceous fungi". Stud Mycol 57 (1): 5"“59. doi:10.3114/sim.2007.57.01. PMC 2104736. PMID 18490993.
7. Holliday, John; Cleaver, Phillip; Lomis-Powers, Megan; Patel, Dinesh (2004). "Analysis of Quality and Techniques for Hybridization of Medicinal Fungus Cordyceps sinensis (Berk.)Sacc. (Ascomycetes)" (PDF). International Journal of Medicinal Mushrooms (New York: Begell House) 6 (2): 152. doi:10.1615/IntJMedMushr.v6.i2.60. ISSN 1521-9437.
8. Holliday, John (2005). "Cordyceps" (PDF). In Coates, Paul M. Encyclopaedia of Dietary Supplements 1. Marcel Dekker. pp. 4 of Cordyceps Chapter.
9. Cordyceps information from Drugs.com.
10. Khan MA, Tania M, Zhang D, Chen H (May 2010). "Cordyceps Mushroom: A Potent Anticancer Nutraceutical". The Open Nutraceuticals Journal 3: 179"“183. doi:10.2174/1876396001003010179.
11. Liu, Wei-Chung; Wang, Shu-Chi; Tsai, Min-Lung; Chen, Meng-Chi; Wang, Ya-Chen; Hong, Ji-Hong; McBride, William H.; Chiang, CS (2006-12). "Protection against Radiation-Induced Bone Marrow and Intestinal Injuries by Cordyceps sinensis, a Chinese Herbal Medicine". Radiation Research 166 (6): 900"“907. doi:10.1667/RR0670.1. PMID 17149981.
12. Ko WS, Hsu SL, Chyau CC, Chen KC, Peng RY (July 2009). "Compound Cordyceps TCM-700C exhibits potent hepatoprotective capability in animal model". Fitoterapia 81 (1): 1"“7. doi:10.1016/j.fitote.2009.06.018. PMID 19596425.
13. Nishizawa K, Torii K, Kawasaki A et al. (September 2007). "Antidepressant-like effect of Cordyceps sinensis in the mouse tail suspension test". Biol. Pharm. Bull. 30 (9): 1758"“1762. doi:10.1248/bpb.30.1758. PMID 17827735.
14. Kiho T, Hui J, Yamane A, Ukai S (December 1993). "Polysaccharides in fungi. XXXII. Hypoglycemic activity and chemical properties of a polysaccharide from the cultural mycelium of Cordyceps sinensis". Biol. Pharm. Bull. 16 (12): 1291"“1293. doi:10.1248/bpb.16.1291. PMID 8130781.
15. Kiho T, Yamane A, Hui J, Usui S, Ukai S (February 1996). "Polysaccharides in fungi. XXXVI. Hypoglycemic activity of a polysaccharide (CS-F30) from the cultural mycelium of Cordyceps sinensis and its effect on glucose metabolism in mouse liver". Biol. Pharm. Bull. 19 (2): 294"“296. doi:10.1248/bpb.19.294. PMID 8850325.
16. Zhao CS, Yin WT, Wang JY et al. (June 2002). "CordyMax Cs-4 improves glucose metabolism and increases insulin sensitivity in normal rats". J Altern Complement Med 8 (3): 309"“314. doi:10.1089/10755530260127998. PMID 12165188.
17. Lo HC, Tu ST, Lin KC, Lin SC (April 2004). "The anti-hyperglycemic activity of the fruiting body of Cordyceps in diabetic rats induced by nicotinamide and streptozotocin". Life Sci. 74 (23): 2897"“2908. doi:10.1016/j.lfs.2003.11.003. PMID 15050427.
18. Li SP, Zhang GH, Zeng Q et al. (June 2006). "Hypoglycemic activity of polysaccharide, with antioxidation, isolated from cultured Cordyceps mycelia". Phytomedicine 13 (6): 428"“433. doi:10.1016/j.phymed.2005.02.002. PMID 16716913.
19. Mackay, Duncan (2001-07-24). "Ma's army on the march again". The Guardian. Retrieved 2010-12-04.
20. Winkler, Daniel (2008). "Yarsa Gunbu (Cordyceps sinensis) and the Fungal Commodification of the Rural Economy in Nepal". Economic Botany 62 (3): 291"“305. doi:10.1007/s12231-008-9038-3
21. Chen J, Zhang W, Lu T, et al. Morphological and genetic characterization of a cultivated Cordyceps sinensis fungus and its polysaccharide component possessing antioxidant property in H22 tumor-bearing mice. Life Sci 5-1-2006;78(23):2742-2748.
22. Kim HG, Shrestha B, Lim SY, et al. Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-kappaB through Akt and p38 inhibition in RAW 264.7 macrophage cells. Eur J Pharmacol 9-18-2006;545(2-3):192-199.
23. Kunwar RM, Nepal BK, Kshhetri HB, et al. Ethnomedicine in Himalaya: a case study from Dolpa, Humla, Jumla and Mustang districts of Nepal. J Ethnobiol Ethnomedicine. 2006;2:27.
24. Lee H, Kim YJ, Kim HW, et al. Induction of apoptosis by Cordyceps militaris through activation of caspase-3 in leukemia HL-60 cells. Biol Pharm Bull. 2006;29(4):670-674.
25. Li FH, Liu P, Xiong WG, Xu GF. [Effects of Cordyceps sinensis on dimethylnitrosamine-induced liver fibrosis in rats]. Zhong.Xi.Yi.Jie.He.Xue.Bao. 2006;4(5):514-517.
26. Li SP, Yang FQ, Tsim KW. Quality control of Cordyceps sinensis, a valued traditional Chinese medicine. J Pharm Biomed.Anal. 8-28-2006;41(5):1571-1584.
27. Li SP, Zhang GH, Zeng Q, et al. Hypoglycemic activity of polysaccharide, with antioxidation, isolated from cultured Cordyceps mycelia. Phytomedicine 2006;13(6):428-433.
28. Liu WC, Wang SC, Tsai ML, et al. Protection against radiation-induced bone marrow and intestinal injuries by Cordyceps sinensis, a Chinese herbal medicine. Radiat.Res 2006;166(6):900-907.
29. Rukachaisirikul V, Chantaruk S, Tansakul C, et al. A cyclopeptide from the Insect pathogenic fungus Cordyceps sp. BCC 1788. J Nat Prod 2006;69(2):305-307.
30. Shao G. [Treatment of hyperlipidemia with cultivated Cordyceps--a double-blind, randomized placebo control trial]. Zhong.Xi.Yi.Jie.He.Za Zhi. 1985;5(11):652-4, 642.
31. Wu WC, Hsiao JR, Lian YY, et al. The apoptotic effect of cordycepin on human OEC-M1 oral cancer cell line. Cancer Chemother.Pharmacol 10-10-2006.
32. Wu Y, Sun H, Qin F, et al. Effect of various extracts and a polysaccharide from the edible mycelia of Cordyceps sinensis on cellular and humoral immune response against ovalbumin in mice. Phytother Res 2006;20(8):646-652.
33. Yoo O, Lee DH. Inhibition of sodium glucose cotransporter-I expressed in Xenopus laevis oocytes by 4-acetoxyscirpendiol from Cordyceps takaomantana (anamorph = Paecilomyces tenuipes). Med Mycol 2006;44(1):79-85.
34. Yu HM, Wang BS, Huang SC, Duh PD. Comparison of protective effects between cultured Cordyceps militaris and natural Cordyceps sinensis against oxidative damage. J Agric.Food Chem 4-19-2006;54(8):3132-3138.
35. Zhang G, Huang Y, Bian Y, et al. Hypoglycemic activity of the fungi Cordyceps militaris, Cordyceps sinensis, Tricholoma mongolicum, and Omphalia lapidescens in streptozotocin-induced diabetic rats. Appl Microbiol Biotechnol 2006;72(6):1152-1156.

36. http://www.ncbi.nlm.nih.gov/pubmed/16354395
37. http://www.ncbi.nlm.nih.gov/pubmed/20650308
38. http://www.ncbi.nlm.nih.gov/pubmed/23189667
39. http://www.ncbi.nlm.nih.gov/pubmed/12736514
40. http://www.ncbi.nlm.nih.gov/pubmed/1392475
41. http://www.ncbi.nlm.nih.gov/pubmed/1597083

Lion’s Mane

  1. Neuronal Health – Can Culinary and Medicinal Mushrooms Help?: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924982/

  2. Chang ST, Buswell JA. Development of the world mushroom industry: Applied mushroom biology and international mushroom organizations. Int J Med Mushrooms. 2008;10:195–208. [Google Scholar]

  3. Wasser SP. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol. 2002;60:258–74. [PubMed] [Google Scholar]

  4. Royse DJ. Foreword to the Fifth international conference on mushroom biology and mushroom products. Acta Edulis Fungi. 2005;12:1–2. [Google Scholar]

  5. Chemical Constituents from Hericium erinaceus Promote Neuronal Survival and Potentiate Neurite Outgrowth via the TrkA/Erk1/2 Pathway : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578049/ 

  6. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. : https://www.ncbi.nlm.nih.gov/pubmed/18844328

  7. Hericium erinaceus: https://en.wikipedia.org/wiki/Hericium_erinaceus

Coconut Water

coconut.png

1. Natural Standard Monograph; Palm Oil; Christopher Chan; 2011

2. "The Journal of Nutrition"; Consumption of a Solid Fat Rich in Lauric Acid Results in a More Favorable Serum Lipid Profile in Healthy Men and Women than Consumption of a Solid Fat Rich in Trans-fatty Acids; Nicole M. deRoos; February 2001

3. European Food Safety Authority Journal; "Scientific Opinion on the Safety of Sucrose Esters of Fatty Acids..."; 2010

4. The AOCS Lipid Library; Commodity Oils and Fats - Palmkernel and Coconut Oils; February 2011

5. "Harvard Health Letter"; Ask the Doctor: I Have Started Noticing More Coconut Oil at the Grocery Store...; Walter Willett; May 2011

6. Beccari, O. The origin and dispersal of cocos nucifera. The Philippine journal of science, C. Botany, v.7, Jan. 1917: 27- 43. http://cocos.arecaceae.com/beccari.pdf

7. Davidson, Alan. Coconut in Penguin companion to food. New York, Penguin Reference, c2002. p. 239-241.

8. Duke, James A. Cocos nucifera L. in Handbook of nuts. Boca Raton, FL, CRC Press, c2001. p. 100-109.

9. Hill, Arthur W. The original home and mode of dispersal of the coconut. Nature, v. 124, July 27, 1929: 133-134, 151-153.

10. Macbean, Valerie. Coconut cookery: a practical cookbook encompassing innovative uses of the tropical drupe Cocus nucifera, accompanied by assorted information and anecdotes ranging from hard data to the frankly frivolous. Berkeley, Frog Ltd., North Atlantic Books, c2001. 198 p.

11. Modern coconut management: palm cultivation and products. Edited by J. G. Ohler. London, Intermediate Technology Publications, 1999. 458 p.

12. Rosengarten, Frederic Jr. Coconuts in The book of edible nuts. Mineola, NY, Dover Publications, 2004. p. 65-93.

13. Woodroof, Jasper Guy. Coconuts: production, processing, products. Westport, CT, AVI Publishing Co., 1970. 241 p.

Acerola Cherry

cherry.png

1. "Prescription for Herbal Healing"; Phyllis A. Balch; 2002.

2. Corren J, Lemay M, Lin Y, Rozga L, Randolph RK.,"Clinical and biochemical effects of a combination botanical product (ClearGuardTM) for allergy: a pilot randomized double-blind placebo-controlled trial." Nutr J. 2008 Jul 14;7(1):20

3. Janick, Jules; Robert E. Paull (2008). The Encyclopedia of Fruit & Nuts. CABI. p. 462. ISBN 978-0-85199-638-7.

4. "Malpighia glabra L.". Germplasm Resources Information Network. United States Department of Agriculture. 2007-02-11. Retrieved 2009-12-16.

5. Johnson, Paul D. (2003). "Acerola (Malpighia glabra L., M. punicifolia M. emarginata DC.) Agriculture, Production, and Nutrition". In Artemis P. Simopoulos; C. Gopalan. Plants in Human Health and Nutrition Policy 91. Karger Publishers. pp. 63"“74. ISBN 978-3-8055-7554-6.

6. "Malpighia glabra L. wild crapemyrtle". PLANTS Database. United States Department of Agriculture. Retrieved 2009-10-17.

7. Mezadri T, VillanËœo M, Fernandez-Pachon M, Garcia-Parrilla M, Troncoso A (2008). "Antioxidant compounds and antioxidant activity in acerola (Malpighia emarginata DC.) fruits and derivatives". Journal of Food Composition and Analysis 21 (4): 282"“290.

8. Assis S, Fernandes F, Martins A, Oliveira O (2008). "Acerola: importance, culture, conditions, production and biochemical aspects". Fruits 63: 93"“101.

9. "Barbados Cherry, Mexican Myrtle, Manzanita, Cerez, Huacacote, Wild Crepe Myrtle, Manyonita, Cerezo de Jamaica, Cerezo de Castillo, Pallo de Gallina, Escobillo, Chia, Arrayncito, Xocat, Xocatatl Malpighia glabra". Benny Simpson's Texas Native Shrubs. Texas A&M University. Retrieved 2009-12-15.

10. "Malpighia glabra L. Malpighiaceae" (PDF). Agroforestree Database 4.0. World Agroforestry Centre. 2009. Retrieved 2009-12-1

11. Vendramini T, Tugo L (2000). "Chemical Composition of acerola fruit (Malpighia punicifolia L.) at three stage of maturity". The Food Chemistry 71: 195"“198.

12. Clein N (1956). "Acerola juice"”The richest known source of Vitamin C: A clinical study in infants". The Journal of pediatrics 48 (2): 140"“145.

13. Kuskoski EM, Asuero AG, Morales MT, Fett R (2006). "Wild fruits and pulps of frozen fruits: antioxidant activity, polyphenols and anthocyanins". Cienc Rural 36 (4 (July/Aug)).

Rosehip

rosehip.png

1. M. B. Goldring and S. R. Goldring, "Osteoarthritis," Journal of Cellular Physiology, vol. 313, pp. 626"“634, 2007.
2. Y. Henrotin, C. Sanchez, and M. Balligand, "Pharmaceutical and nutraceutical management of canine osteoarthritis: present and future perspectives," Veterinary Journal, vol. 170, no. 1, pp. 113"“123, 2005.
3. J. A. Buckwalter, J. Martin, and H. J. Mankin, "Synovial joint degeneration and the syndrome of osteoarthritis," Instructional Course Lectures, vol. 49, pp. 481"“489, 2000.
4. M. B. Goldring, "The role of the chondrocyte in osteoarthritis," Arthritis and Rheumatism, vol. 43, no. 9, pp. 1916"“1926, 2000.
5. M. Shakibaei, "Inhibition of chondrogenesis by integrin antibody in vitro," Experimental Cell Research, vol. 240, no. 1, pp. 95"“106, 1998.
6. L. Cao, V. Lee, M. E. Adams et al., "β1-Integrin-collagen interaction reduces chondrocyte apoptosis," Matrix Biology, vol. 18, no. 4, pp. 343"“355, 1999.
7. M. Shakibaei, T. John, P. De Souza, R. Rahmanzadeh, and H. J. Merker, "Signal transduction by β1 integrin receptors in human chondrocytes in vitro: collaboration with the insulin-like growth factor-I receptor," Biochemical Journal, vol. 342, no. 3, pp. 615"“623, 1999.
8. M. Shakibaei, G. Schulze-Tanzil, P. De Souza et al., "Inhibition of mitogen-activated protein kinase kinase induces apoptosis of human chondrocytes," The Journal of Biological Chemistry, vol. 276, no. 16, pp. 13289"“13294, 2001.
9. P. G. Todhunter, S. A. Kincaid, R. J. Todhunter et al., "Immunohistochemical analysis of an equine model of synovitis-induced arthritis," American Journal of Veterinary Research, vol. 57, no. 7, pp. 1080"“1093, 1996.
10. T. Aigner, K. Fundel, J. Saas et al., "Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis," Arthritis and Rheumatism, vol. 54, no. 11, pp. 3533"“3544, 2006.
11. K. J. Smith, A. L. Bertone, S. E. Weisbrode, and M. Radmacher, "Gross, histologic, and gene expression characteristics of osteoarthritic articular cartilage of the metacarpal condyle of horses," American Journal of Veterinary Research, vol. 67, no. 8, pp. 1299"“1306, 2006.
12. K. von der Mark, T. Kirsch, A. Nerlich et al., "Type X collagen synthesis in human osteoarthritic cartilage: indication of chondrocyte hypertrophy," Arthritis and Rheumatism, vol. 35, no. 7, pp. 806"“811, 1992.
13. F. J. Blanco, R. Guitian, E. Vázquez-Martul, F. J. De Toro, and F. Galdo, "Osteoarthritis chondrocytes die by apoptosis: a possible pathway for osteoarthritis pathology," Arthritis and Rheumatism, vol. 41, no. 2, pp. 284"“289, 1998.
14. M. B. Goldring, "The role of cytokines as inflammatory mediators in osteoarthritis: lessons from animal models," Connective Tissue Research, vol. 40, no. 1, pp. 1"“11, 1999.
15. J. R. Robbins, B. Thomas, L. Tan, et al., "Immortalized human adult articular chondrocytes maintain cartilage-specific phenotype and responses to interleukin-1β," Arthritis and Rheumatism, vol. 43, no. 10, pp. 2189"“2201, 2000.
16. A. Kumar, Y. Takada, A. M. Boriek, and B. B. Aggarwal, "Nuclear factor-κB: its role in health and disease," Journal of Molecular Medicine, vol. 82, no. 7, pp. 434"“448, 2004.
17. K. Riehemann, B. Behnke, and K. Schulze-Osthoff, "Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-κB," FEBS Letters, vol. 442, no. 1, pp. 89"“94, 1999.
18. S. Murakami, V. Lefebvre, and B. De Crombrugghe, "Potent inhibition of the master chondrogenic factor Sox9 gene by interleukin-1 and tumor necrosis factor-α," The Journal of Biological Chemistry, vol. 275, no. 5, pp. 3687"“3692, 2000.
19. D. M. Gerlag, L. Ransone, P. P. Tak et al., "The effect of a T cell-specific NF-κB inhibitor on in vitro cytokine production and collagen-induced arthritis," Journal of Immunology, vol. 165, no. 3, pp. 1652"“1658, 2000.
20. N. G. Murphy and R. B. Zurier, "Treatment of rheumatoid arthritis," Current Opinion in Rheumatology, vol. 3, no. 3, pp. 441"“448, 1991.
21. K. P. Khalsa, "Frequently asked questions (FAQ)," Journal of Herbal Pharmacotherapy, vol. 6, no. 1, pp. 77"“87, 2006.
22. S. N. Willich, K. Rossnagel, S. Roll et al., "Rose hip herbal remedy in patients with rheumatoid arthritis"”a randomised controlled trial," Phytomedicine, vol. 17, no. 2, pp. 87"“93, 2010.
23. X. Tao, H. Schulze-Koops, L. Ma, J. Cai, Y. Mao, and P. E. Lipsky, "Effects of Tripterygium wilfordii Hook F extracts on induction of cyclooxygenase 2 activity and prostaglandin E2 production," Arthritis and Rheumatism, vol. 41, no. 1, pp. 130"“138, 1998.
24. N. Lin, T. Sato, and A. Ito, "Triptolide, a novel diterpenoid triepoxide from Tripterygium wilfordii Hook. f., suppresses the production and gene expression of pro-matrix metalloproteinases 1 and 3 and augments those of tissue inhibitors of metalloproteinases 1 and 2 in human synovial fibroblasts," Arthritis and Rheumatism, vol. 44, no. 9, pp. 2193"“2200, 2001.
25. L. W. Whitehouse, M. Znamirowska, and C. J. Paul, "Devil's Claw (Harpagophytum procumbens): no evidence for anti-inflammatory activity in the treatment of arthritic disease," Canadian Medical Association Journal, vol. 129, no. 3, pp. 249"“251, 1983.
26. C. L. Shen, K. J. Hong, and S. W. Kim, "Effects of ginger (Zingiber officinale Rosc.) on decreasing the production of inflammatory mediators in sow osteoarthrotic cartilage explants," Journal of Medicinal Food, vol. 6, no. 4, pp. 323"“328, 2003.
27. L. C. Mishra, B. B. Singh, and S. Dagenais, "Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review," Alternative Medicine Review, vol. 5, no. 4, pp. 334"“346, 2000. View at Scopus
28. E. Ernst, "Complementary and alternative medicine in rheumatology," Best Practice and Research, vol. 14, no. 4, pp. 731"“749, 2000.
29. L. Long, K. Soeken, and E. Ernst, "Herbal medicines for the treatment of osteoarthritis: a systematic review," Rheumatology, vol. 40, no. 7, pp. 779"“793, 2001.
30. J. E. Chrubasik, B. D. Roufogalis, H. Wagner, and S. A. Chrubasik, "A comprehensive review on nettle effect and efficacy profiles, Part I: herba urticae," Phytomedicine, vol. 14, no. 6, pp. 423"“435, 2007.
31. G. Schulze-Tanzil, P. De Souza, B. Behnke, S. Klingelhoefer, A. Scheid, and M. Shakibaei, "Effects of the antirheumatic remedy Hox alpha"”a new stinging nettle leaf extract"”on matrix metalloproteinases in human chondrocytes in vitro," Histology and Histopathology, vol. 17, no. 2, pp. 477"“485, 2002.
32. M. Shakibaei and P. De Souza, "Differentiation of mesenchymal limb bud cells to chondrocytes in alginate beads," Cell Biology International, vol. 21, no. 2, pp. 75"“86, 1997.
33. M. Shakibaei, T. John, G. Schulze-Tanzil, I. Lehmann, and A. Mobasheri, "Suppression of NF-κB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: implications for the treatment of osteoarthritis," Biochemical Pharmacology, vol. 73, no. 9, pp. 1434"“1445, 2007.
34. S. Miyamoto, M. Maki, M. J. Schmitt, M. Hatanaka, and I. M. Verma, "Tumor necrosis factor α-induced phosphorylation of IκBα is a signal for its degradation but not dissociation from NF-κB," Proceedings of the National Academy of Sciences of the United States of America, vol. 91, no. 26, pp. 12740"“12744, 1994.
35. A. Vinitsky, C. Michaud, J. C. Powers, and M. Orlowski, "Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex," Biochemistry, vol. 31, no. 39, pp. 9421"“9428, 1992.
36. R. O. Sanderson, C. Beata, R. M. Flipo et al., "Systematic review of the management of canine osteoarthritis," Veterinary Record, vol. 164, no. 14, pp. 418"“424, 2009. View at Scopus
37. T. P. N. Talorete, M. Bouaziz, S. Sayadi, and H. Isoda, "Influence of medium type and serum on MTT reduction by flavonoids in the absence of cells," Cytotechnology, vol. 52, no. 3, pp. 189"“198, 2006.
38. M. Shakibaei, P. De Souza, and H. J. Merker, "Integrin expression and collagen type II implicated in maintenance of chondrocyte shape in monolayer culture: an immunomorphological study," Cell Biology International, vol. 21, no. 2, pp. 115"“125, 1997.
39. A. Mobasheri, S. D. Carter, P. Martín-Vasallo, and M. Shakibaei, "Integrins and stretch activated ion channels; putative components of functional cell surface mechanoreceptors in articular chondrocytes," Cell Biology International, vol. 26, no. 1, pp. 1"“18, 2002.
40. S. M. Albelda and C. A. Buck, "Integrins and other cell adhesion molecules," The FASEB Journal, vol. 4, no. 11, pp. 2868"“2880, 1990. View at Scopus
41. J. P. Schmitz, D. D. Dean, Z. Schwartz et al., "Chondrocyte cultures express matrix metalloproteinase mRNA and immunoreactive protein; stromelysin-1 and 72 kDa gelatinase are localized in extracellular matrix vesicles," Journal of Cellular Biochemistry, vol. 61, no. 3, pp. 375"“391, 1996.
42. D. H. Manicourt, N. Fujimoto, K. Obata, and E. J. M. A. Thonar, "Levels of circulating collagenase, stromelysin-1, and tissue inhibitor of matrix metalloproteinases 1 in patients with rheumatoid arthritis: relationship to serum levels of antigenic keratan sulfate and systemic parameters of inflammation," Arthritis and Rheumatism, vol. 38, no. 8, pp. 1031"“1039, 1995.
43. G. Keyszer, I. Lambiri, R. Nagel et al., "Circulating levels of matrix metalloproteinases MMP-3 and MMP-1, tissue inhibitor of metalloproteinases 1 (TIMP-1), and MMP-1/TIMP-1 complex in rheumatic disease. Correlation with clinical activity of rheumatoid arthritis versus other surrogate markers," The Journal of Rheumatology, vol. 26, no. 2, pp. 251"“258, 1999. View at Scopus
44. I. C. Chikanza and L. Fernandes, "Novel strategies for the treatment of osteoarthritis," Expert Opinion on Investigational Drugs, vol. 9, no. 7, pp. 1499"“1510, 2000. View at Scopus
45. E. Nédélec, A. Abid, C. Cipolletta et al., "Stimulation of cyclooxygenase-2-activity by nitric oxide-derived species in rat chondrocyte: lack of contribution to loss of cartilage anabolism," Biochemical Pharmacology, vol. 61, no. 8, pp. 965"“978, 2001.
46. C. Csaki, N. Keshishzadeh, K. Fischer, and M. Shakibaei, "Regulation of inflammation signalling by resveratrol in human chondrocytes in vitro," Biochemical Pharmacology, vol. 75, no. 3, pp. 677"“687, 2008.
47. C. Csaki, A. Mobasheri, and M. Shakibaei, "Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis," Arthritis Research & Therapy, vol. 11, no. 6, article R165, 2009.
48. K. Yamamoto, T. Arakawa, N. Ueda, and S. Yamamoto, "Transcriptional roles of nuclear factor κB and nuclear factor-interleukin-6 in the tumor necrosis factor α-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells," The Journal of Biological Chemistry, vol. 270, no. 52, pp. 31315"“31320, 1995.
49. M. Hebbar, J.-P. Peyrat, L. Hornez, P.-Y. Hatron, E. Hachulla, and B. Devulder, "Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor κB: differential regulation of collagenase 1 and collagenase 3," Arthritis and Rheumatism, vol. 43, no. 4, pp. 801"“811, 2000.
50. K. W. McIntyre, D. J. Shuster, K. M. Gillooly et al., "A highly selective inhibitor of IκB kinase, BMS-345541, blocks both joint inflammation and destruction in collagen-induced arthritis in mice," Arthritis and Rheumatism, vol. 48, no. 9, pp. 2652"“2659, 2003.
51. I. Kou and S. Ikegawa, "SOX9-dependent and -independent transcriptional regulation of human cartilage link protein," The Journal of Biological Chemistry, vol. 279, no. 49, pp. 50942"“50948, 2004.
52. http://science.naturalnews.com
53. http://news.bbc.co.uk
54. http://www.nursinginpractice.com
55. http://www.telegraph.co.uk
56.http://www.naturalnews.com/043134_vitamin_C_intravenous_infusions_COPD.html
57. http://www.eurekalert.org/pub_releases/2013-11/aps-vcc110713.php
58.http://ajpregu.physiology.org/content/ajpregu/early/2013/09/20/ajpregu.00360.2013.full.pdf
59. http://www.vitamincfoundation.org/NaturalC.pdf

60. http://lpi.oregonstate.edu/infocenter/vitamins/vitaminC/vitCform.html
MEK1/2 and NF-kappaB signaling pathways," Journal of Cellular Physiology, vol. 197, no. 3, pp. 356"“369, 2003. View at Scopus

62. http://www.ars.usda.gov/main/site_main.htm?modecode=80-40-05-25

63. http://www.ars-grin.gov/duke/

Wild blueberry

blueberry (1).png

1. Adams LS, Phung S, Yee N et al. Blueberry Phytochemicals Inhibit Growth and Metastatic Potential of MDA-MB-231 Breast Cancer Cells Through Modulation of the Phosphatidylinositol 3-Kinase Pathway. Cancer Res. 2010 May 1; 70(9): 3594-3605. Published online 2010 April 13. doi: 10.1158/0008-5472.CAN-09-3565. 2010.
2. Ahmet I, Spangler E, Shukitt-Hale B et al. Blueberry-Enriched Diet Protects Rat Heart from Ischemic Damage. PLoS ONE. 2009; 4(6): e5954. Published online 2009 June 18. doi: 10.1371/journal.pone.0005954. 2009.
3. Basu A, Du M, Leyva MJ et al. Blueberries Decrease Cardiovascular Risk Factors in Obese Men and Women with Metabolic Syndrome. The Journal of Nutrition. Bethesda: Sep 2010. Vol. 140, Iss. 9; p. 1582-1587. 2010.
4. Basu A, Rhone M and Lyons TJ. Berries: emerging impact on cardiovascular health. Nutr Rev. 2010 Mar;68(3):168-77. Review. 2010.
5. DeFuria J, Bennett G, Strissel KJ et al. Dietary . Dietary Blueberry Attenuates Whole-Body Insulin Resistance in High Fat-Fed Mice by Reducing Adipocyte Death and Its Inflammatory Sequelae. J Nutr. 2009 August; 139(8): 1510-1516. doi: 10.3945/jn.109.105155. 2009.
6. Grace MH, Ribnicky DM, Kuhn P et al. Hypoglycemic activity of a novel Anthocyanin-rich formulation from Lowbush Blueberry, Vaccinium angustifolium. Phytomedicine. 2009 May; 16(5): 406-415. 2009.

7. Basu A, Du M, Leyva MJ, Sanchez K, Betts NM, Wu M, Aston CE, Lyons TJ. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr. 2010 Sep;140(9):1582-7. doi: 10.3945/jn.110.124701. Epub 2010 Jul 21.

8. Krikorian R, Shidler MD, Nash TA, Kalt W, Vinqvist-Tymchuk MR, Shukitt-Hale B, Joseph JA. Blueberry supplementation improves memory in older adults. J Agric Food Chem. 2010 Apr 14;58(7):3996-4000. doi: 10.1021/jf9029332.

9. Hurst RD, Wells RW, Hurst SM et al. Blueberry fruit polyphenolics suppress oxidative stress-induced skeletal muscle cell damage in vitro. Mol Nutr Food Res. 2010 Mar;54(3):353-63. 2010.
10. Jenkins DJA, Ssrichaikul K, Kendall CWC et al. The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes. Diabetologia. 2011 February; 54(2): 271-279. 2011.
11. Krikorian R, Shidler MD, Nash TA et al. Blueberry Supplementation Improves Memory in Older Adults. J Agric Food Chem. 2010 April 14; 58(7): 3996-4000. 2010.
12. Lohachoompol V, Srzednicki G, and Craske J. The Change of Total Anthocyanins in Blueberries and Their Antioxidant Effect After Drying and Freezing. J Biomed Biotechnol. 2004 December 1; 2004(5): 248-252. 2004.
13. Mannal P, McDonald D and McFadden D. Pterostilbene and tamoxifen show an additive effect against breast cancer in vitro. Am J Surg. 2010 Nov;200(5):577-80. 2010.
14. Mizuno CS and Rimando AM. Blueberries and Metabolic Syndrome. Silpakorn University Science and Technology Journal Year: 2009 Vol: 3 Issue: 2 Pages/record No.: 7-17. 2009.
15. Paul S, DeCastro AJ, Lee HJ et al. Dietary intake of pterostilbene, a constituent of blueberries, inhibits the beta-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats. Carcinogenesis. 2010 Jul;31(7):1272-8. Epub 2010 Jan 8. 2010.
16. Paul S, Rimando AM, Lee HJ et al. Anti-inflammatory action of pterostilbene is mediated through the p38 MAPK pathway in colon cancer cells. Cancer Prev Res (Phila). 2009 July; 2(7): 650-657. Published online 2009 June 23. doi: 10.1158/1940-6207.CAPR-08-0224. 2009.
17. Sablani SS, Andrews PK, Davies NM et al. Effect of thermal treatments on phytochemicals in conventionally and organically grown berries. J Sci Food Agric. 2010 Apr 15;90(5):769-78. 2010.
18. Scibisz I and Mitek M. The changes of antioxidant properties in highbush blueberries (Vaccinium corymbosum L.) during freezing and long-term frozen storage. Acta Scientiarum Polonorum : Technologia Alimentaria Year: 2007 Vol: 6 Issue: 4 Pages/record No.: 75-81. 2007.
19. Simmen FA, Frank JA, Wu X et al. Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon. BMC Gastroenterol. 2009; 9: 67. Published online 2009 September 16. doi: 10.1186/1471-230X-9-67. 2009.
20. Still AJ, Cash KC, Johnson WD et al. Bioactives in Blueberries Improve Insulin Sensitivity in Obese, Insulin-Resistant Men and Women. The Journal of Nutrition. Bethesda: Oct 2010. Vol. 140, Iss. 10; p. 1764-1768. 2010.
21. Stoner GD, Want LS, Seguin C et al. Multiple Berry Types Prevent N-nitrosomethylbenzylamine-Induced Esophageal Cancer in Rats. Pharm Res. 2010 June; 27(6): 1138-1145. 2010.
22. Vuong T, Matar C, Ramassamy C et al. Biotransformed blueberry juice protects neurons from hydrogen peroxide-induced oxidative stress and mitogen-activated protein kinase pathway alterations. Br J Nutr. 2010 Sep;104(5):656-63. Epub 2010 May 12. 2010.
23. Wang SY, Chen CT, Sciarappa W et al. Fruit quality, antioxidant capacity, and flavonoid content of organically and conventionally grown blueberries. J Agric Food Chem. 2008 Jul 23;56(14):5788-94. Epub 2008 Jul 1. 2008.
24. Wu X, Kang J, Xie C et al. Dietary Blueberries Attenuate Atherosclerosis in Apolipoprotein E-Deficient Mice by Upregulating Antioxidant Enzyme Expression. J. Nutr. September 1, 2010 vol. 140 no. 9 1628-1632. 2010.
25. Litz, Richard E (2005). Google Books -- Biotechnology of fruit and nut crops By Richard E. Litz. ISBN 9780851996622.
26. a b Naumann, W. D. (1993). "Overview of the Vaccinium Industry in Western Europe". In K. A. Clayton-Greene. Fifth International Symposium on Vaccinium Culture. Wageningen, the Netherlands: International Society for Horticultural Science. pp. 53"“58. ISBN 978-90-6605-475-2. OCLC 29663461.
27. http://www.jerseyfruit.com/health_blueberries.asp
28. "Plants Profile: Vaccinium corymbosum L., Highbush blueberry". US Department of Agriculture, National Resources Conservation Service. 2013. Retrieved 30 April 2013.
29. "Wild Blueberry Network Information Centre". Nsac.ns.ca. Retrieved 2011-10-11.
30. "Blueberry Growing Comes to the National Agricultural Library". Agricultural Research Magazine. May/June 2011 - Vol. 59, No. 5. Retrieved 17 June 2011.
31. "The History of ''Whitesbog Village''". Whitesbog.org. Retrieved 2011-10-11.
32. "Agricultural Marketing Resource Center". Agmrc.org. Retrieved 2011-10-11.
33. http://www.nlm.nih.gov/medlineplus/druginfo/natural/1013.html
34. "US Highbush Blueberry Council". Blueberry.org. Retrieved 2011-10-11.
35. "State.nj.us". State.nj.us. 2010-06-17. Retrieved 2011-10-11.
36. Scrivener L. Economy singing the blues, but berries are booming: Health-conscious consumers can't get enough of Canada's most valuable fruit crop, Toronto Star, Jul 28, 2008

37. British Columbia Blueberry Council
38. "United States Highbush Blueberry Council". Blueberry.org. Retrieved 2011-10-11.
39. Yarborough DE. Factors contributing to the increase in productivity in the wild blueberry industry, Small Fruits Review, 3(1-2), July 2004, 33-43, Abstract
40. Nova Scotia: Official emblems and symbols
41. "Wild Blueberries, Carrots, Cranberries, Battered Vegetables". Oxfordfrozenfoods.com. Retrieved 2009-12-06.
42. a b Australian Blueberry Growers' Association
43. Clayton-Greene
44. U.S. Department of Agriculture GAIN Report, Retrieved June 30, 2011
45. Pirovano, Francisco (12 January 2005). "Argentina Blueberries Voluntary 2005". GAIN Report. Foreign Agricultural Service. Retrieved 22 June 2009.
46. Asoex.cl, 2007)
47. Fedefruta.cl, 2007
48. Homemade blueberry wine recipe, MakeWineFromHome.net
49. In-depth nutrition information on raw blueberries, Nutritiondata.com
50. "Antioxidants and Cancer Prevention". Fact Sheet. National Cancer Institute. Cancerresearchsociety.ca
51. Seeram NP, Adams LS, Zhang Y, et al. (December 2006). "Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro". J Agric Food Chem. 54 (25): 9329"“39. doi:10.1021/jf061750g. ISSN 0021-8561. PMID 17147415.
52. Neto CC (June 2007). "Cranberry and blueberry: evidence for protective effects against cancer and vascular diseases". Mol Nutr Food Res. 51 (6): 652"“64. doi:10.1002/mnfr.200600279. ISSN 1613-4125. PMID 17533651.
53. Srivastava A, Akoh CC, Fischer J, Krewer G (April 2007). "Effect of anthocyanin fractions from selected cultivars of Georgia-grown blueberries on apoptosis and phase II enzymes". J Agric Food Chem. 55 (8): 3180"“5. doi:10.1021/jf062915o. ISSN 0021-8561. PMID 17381106.
54. Schmidt BM, Erdman JW, Lila MA (January 2006). "Differential effects of blueberry proanthocyanidins on androgen sensitive and insensitive human prostate cancer cell lines". Cancer Lett. 231 (2): 240"“6. doi:10.1016/j.canlet.2005.02.003. ISSN 0304-3835. PMID 16399225.
55. Yi W, Fischer J, Krewer G, Akoh CC (September 2005). "Phenolic compounds from blueberries can inhibit colon cancer cell proliferation and induce apoptosis". J Agric Food Chem. 53 (18): 7320"“9. doi:10.1021/jf051333o. ISSN 0021-8561. PMID 16131149.
56. Russell WR, Labat A, Scobbie L, Duncan SH (June 2007). "Availability of blueberry phenolics for microbial metabolism in the colon and the potential inflammatory implications". Mol Nutr Food Res. 51 (6): 726"“31. doi:10.1002/mnfr.200700022. ISSN 1613-4125. PMID 17487929.
57. Rimando AM, Kalt W, Magee JB, Dewey J, Ballington JR (July 2004). "Resveratrol, pterostilbene, and piceatannol in vaccinium berries". J Agric Food Chem. 52 (15): 4713"“9. doi:10.1021/jf040095e. ISSN 0021-8561. PMID 15264904.
58. Kalt W, Ryan DA, Duy JC, Prior RL, Ehlenfeldt MK, Vander Kloet SP (October 2001). "Interspecific variation in anthocyanins, phenolics, and antioxidant capacity among genotypes of highbush and lowbush blueberries (Vaccinium section cyanococcus spp.)". J Agric Food Chem. 49 (10): 4761"“7. doi:10.1021/jf010653e. ISSN 0021-8561. PMID 11600018.
59. Sweeney MI, Kalt W, MacKinnon SL, Ashby J, Gottschall-Pass KT (December 2002). "Feeding rats diets enriched in lowbush blueberries for six weeks decreases ischemia-induced brain damage". Nutr Neurosci. 5 (6): 427"“31. doi:10.1080/1028415021000055970. ISSN 1028-415X. PMID 12509072.
60. Wang Y, Chang CF, Chou J, et al. (May 2005). "Dietary supplementation with blueberries, spinach, or spirulina reduces ischemic brain damage". Exp Neurol. 193 (1): 75"“84. doi:10.1016/j.expneurol.2004.12.014. ISSN 0014-4886. PMID 15817266.
61. "The benefits of berries". Chicago Tribune. 2011-03-03.
62. Kalea AZ, Lamari FN, Theocharis AD, et al. (February 2006). "Wild blueberry (Vaccinium angustifolium) consumption affects the composition and structure of glycosaminoglycans in Sprague-Dawley rat aorta". J Nutr Biochem. 17 (2): 109"“16. doi:10.1016/j.jnutbio.2005.05.015. ISSN 0955-2863. PMID 16111874.
63. Kalt W, Foote K, Fillmore SA, Lyon M, Van Lunen TA, McRae KB (July 2008). "Effect of blueberry feeding on plasma lipids in pigs". Br J Nutr. 100 (1): 70"“8. doi:10.1017/S0007114507877658. ISSN 0007-1145. PMID 18081945.
64. Krikorian R et al. (2010). "Blueberry Supplementation Improves Memory in Older Adults". J Agric Food Chem. 58 (7): 3996"“4000. doi:10.1021/jf9029332. PMC 2850944. PMID 20047325.
65. "Catching the Toxic Drift: How Pesticides Used in the Blueberry Industry Threaten Our Communities, Our Water and the Environment". Environment Maine. 2005-08-16. Retrieved 2011-10-11.
66. "Measure E8: Pesticide Residues on Foods Frequently Consumed by Children". EPA. November 2010. Retrieved 9 September 2012.
67. "EWG'S 2011 Shopper's Guide Helps Cut Consumer Pesticide Exposure | Environmental Working Group". Ewg.org. Retrieved 2011-10-11.
68."Executive Summary | EWG's Shopper's Guide to Pesticides | Environmental Working Group". EWG.org. Retrieved 2011-10-11.

69. http://www.reuters.com/article/2015/02/06/us-blood-pressure-women-blueberries-idUSKBN0LA23F20150206

70. http://www.andjrnl.org/article/S2212-2672(14)01633-5/abstract?cc=y

71. http://ndb.nal.usda.gov/ndb/foods

72. http://www.ars-grin.gov/duke/

Red Raspberry

closeup-shot-cute-fresh-raspberries-one-

1. Huxley, A., ed. (1992). New RHS Dictionary of Gardening. Macmillan ISBN 0-333-47494-5.
2. Strick, B.C. "Growing Raspberries in Your Home Garden". Growing Small Fruits. Oregon State University Extension Service. Retrieved 18 August 2011.
3. "Health and healing fact sheets, Red Raspberries".
4. Iannetta, P. P. M.; Wyman, M.; Neelam, A.; Jones, C.; Taylor, M. A.; Davies, H. V.; Sexton, R. (December 2000). "A causal role for ethylene and endo-beta-1,4-glucanase in the abscission of red-raspberry (Rubus idaeus) drupelets". Physiol Plant 110 (4): 535"“543. doi:10.1111/j.1399-3054.2000.1100417.x.
5. World's Healthiest Foods, in-depth nutrient profile for raspberries. Whfoods.org. Retrieved on 2012-09-24.
6. Journal of Agricultural and Food Chemistry Presents Research from the 2007 International Berry Health Benefits Symposium, Journal of Agricultural and Food Chemistry ACS Publications, February 2008
7. Carvalho, Elisabete; Fraser, P.D.; Martens, S. (2013). "Carotenoids and tocopherols in yellow and red raspberries". Food Chemistry 139: 744"“752. doi:10.1016/j.foodchem.2012.12.047.
8. Liu M, Li XQ, Weber C, Lee CY, Brown J, Liu RH (May 2002). "Antioxidant and antiproliferative activities of raspberries". J. Agric. Food Chem. 50 (10): 2926"“30. doi:10.1021/jf0111209. PMID 11982421.
9. Heinonen M (June 2007). "Antioxidant activity and antimicrobial effect of berry phenolics"”a Finnish perspective". Mol Nutr Food Res 51 (6): 684"“91. doi:10.1002/mnfr.200700006. PMID 17492800.
10. Cerdá B, Tomás-Barberán FA, Espín JC (January 2005). "Metabolism of antioxidant and chemopreventive ellagitannins from strawberries, raspberries, walnuts, and oak-aged wine in humans: identification of biomarkers and individual variability". J. Agric. Food Chem. 53 (2): 227"“35. doi:10.1021/jf049144d. PMID 15656654.
11. "Statistics from: Food And Agricultural Organization of United Nations: Economic And Social Department: The Statistical Division". UN Food and Agriculture Organization Corporate Statistical Database.
12. RHS Plant Selector Rubus idaeus 'Glen Moy' PBR (F) AGM / RHS Gardening. Apps.rhs.org.uk. Retrieved on 2012-09-24.
13. RHS Plant Selector Rubus idaeus 'Malling Jewel' (F) AGM / RHS Gardening. Apps.rhs.org.uk. Retrieved on 2012-09-24.
14. RHS Plant Selector Rubus idaeus 'Glen Ample' PBR (F) AGM / RHS Gardening. Apps.rhs.org.uk. Retrieved on 2012-09-24.
15. RHS Plant Selector Rubus idaeus 'Glen Prosen' PBR (F) AGM / RHS Gardening. Apps.rhs.org.uk. Retrieved on 2012-09-24.
16. RHS Plant Selector Rubus idaeus 'Leo' PBR (F) AGM / RHS Gardening. Apps.rhs.org.uk. Retrieved on 2012-09-24.
17. RHS Plant Selector Rubus idaeus 'Malling Admiral' (F) AGM / RHS Gardening. Apps.rhs.org.uk. Retrieved on 2012-09-24.
18. RHS Plant Selector Rubus idaeus 'Autumn Bliss' (F) AGM / RHS Gardening. Apps.rhs.org.uk. Retrieved on 2012-09-24.
19. Spooner farms certified raspberry Plants "Planting Information"
20. Aiyer HS, Li Y, Liu QH et al. Dietary freeze-dried black raspberry's effect on cellular antioxidant status during reflux-induced esophagitis in rats. Nutrition, Volume 27, Issue 2, February 2011, Pages 182-187.
21. Ali L, Svensson B, Alsanius BW et al. Late season harvest and storage of Rubus berries-Major antioxidant and sugar levels. Scientia Horticulturae, Volume 129, Issue 3, 27 June 2011, Pages 376-381.
22. Beekwilder J, Hall RD and de Vos CH. Identification and dietary relevance of antioxidants from raspberry. Biofactors. 2005;23(4):197-205. 2005.
23. Bobinaite R, Viskelis P and Venskutonis PR. Variation of total phenolics, anthocyanins, ellagic acid and radical scavenging capacity in various raspberry (Rubus spp.) cultivars. Food Chemistry, Volume 132, Issue 3, 1 June 2012, Pages 1495-1501.
24. Borquez RM, Canales ER and Redon JP. Osmotic dehydration of raspberries with vacuum pretreatment followed by microwave-vacuum drying. Journal of Food Engineering, Volume 99, Issue 2, July 2010, Pages 121-127.
25. Bowen-Forbes CS, Zhang Y and Nair MG. Anthocyanin content, antioxidant, anti-inflammatory and anticancer properties of blackberry and raspberry fruits. Journal of Food Composition and Analysis, Volume 23, Issue 6, September 2010, Pages 554-560.
26. Cekic C and Ozgen M. Comparison of antioxidant capacity and phytochemical properties of wild and cultivated red raspberries (Rubus idaeus L.). Journal of Food Composition and Analysis, Volume 23, Issue 6, September 2010, Pages 540-544.
27. Goto T, Teraminami A, Lee JY et al. Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese"“diabetic mice. The Journal of Nutritional Biochemistry, Volume 23, Issue 7, July 2012, Pages 768-776.
28. Haffner K, Rosenfeld HJ, Skrede G et al. Quality of red raspberry Rubus idaeus L. cultivars after storage in controlled and normal atmospheres. Postharvest Biology and Technology, Volume 24, Issue 3, April 2002, Pages 279-289.
29. Jeong JB and Jeong HJ. Rheosmin, a naturally occurring phenolic compound inhibits LPS-induced iNOS and COX-2 expression in RAW264.7 cells by blocking NF-kappa B activation pathway. Food and Chemical Toxicology, Volume 48, Issues 8"“9, August"“September 2010, Pages 2148-2153.
30. Jeong JH, Jung J, Lee SR et al. Anti-oxidant, anti-proliferative and anti-inflammatory activities of the extracts from black raspberry fruits and wine. Food Chemistry, Volume 123, Issue 2, 15 November 2010, Pages 338-344.
31. Jin P, Wang SY, Gao H et al. Effect of cultural system and essential oil treatment on antioxidant capacity in raspberries. Food Chemistry, Volume 132, Issue 1, 1 May 2012, Pages 399-405.
32. McDougall GJ, Kulkarnni NN and Stewart D. Berry polyphenols inhibit pancreatic lipase activity in vitro. Food Chemistry, Volume 115, Issue 1, 1 July 2009, Pages 193-199.
33. Miromoto C, Satoh Y, Hara M et al. Anti-obese action of raspberry ketone. Life Sciences, Volume 77, Issue 2, 27 May 2005, Pages 194-204.
34. Ochoa MR, Kesseler AG, Vullioud MB et al. Physical and Chemical Characteristics of Raspberry Pulp: Storage Effect on Composition and Color. LWT - Food Science and Technology, Volume 32, Issue 3, May 1999, Pages 149-153.
35. Park KS. Raspberry ketone increases both lipolysis and fatty acid oxidation in 3T3-L1 adipocytes. Planta Med. 2010 Oct;76(15):1654-8. Epub 2010 Apr 27.
36. Piljac-Zegarac J and Samec D. Antioxidant stability of small fruits in postharvest storage at room and refrigerator temperatures. Food Research International, Volume 44, Issue 1, January 2011, Pages 345-350.
37. Ravoori S, Vadhanam MV, Aqil F et al. Inhibition of estrogen-mediated mammary tumorigenesis by blueberry and black raspberry. J Agric Food Chem. 2012 Jun 6;60(22):5547-55. Epub 2012 May 22.
38. Rosillo MA, Sanchez-Hildago M, Cardeno A et al. Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn's disease. Biochemical Pharmacology, Volume 82, Issue 7, 1 October 2011, Pages 737-745
39. Ross HA, McDougall GJ and Stewart D. Antiproliferative activity is predominantly associated with ellagitannins in raspberry extracts. Phytochemistry, Volume 68, Issue 2, January 2007, Pages 218-228.
40. Sarvikivi E, Roivainen M, Maunula L et al. Multiple norovirus outbreaks linked to imported frozen raspberries. Epidemiol Infect. 2012 Feb;140(2):260-7. Epub 2011 Mar 22.
41. Stober GD, Wang LS, Zikri N et al. Cancer prevention with freeze-dried berries and berry components. Seminars in Cancer Biology, Volume 17, Issue 5, October 2007, Pages 403-410.
42. U.S. Department of Agriculture, Economic Research Service (USDA/ERS). (2011). Fruit situation and outlook yearbook, October 2011.
43. U.S. Department of Agriculture, Economic Research Service (USDA/ERS). (2011). Vegetables and melons yearbook data, May 2011.
44. Wang SY, Chen CT and Want CY. The influence of light and maturity on fruit quality and flavonoid content of red raspberries. Food Chemistry, Volume 112, Issue 3, 1 February 2009, Pages 676-684.
45. Wu X, Beecher GR, Holden JM et al. Concentrations of Anthocyanins in Common Foods in the United States and Estimation of Normal Consumption. J Agric Food Chem. 2006 May 31;54(11):4069-4075. 2006.
46. Zhang L, Li J, Hogan S et al. Inhibitory effect of raspberries on starch digestive enzyme and their antioxidant properties and phenolic composition. Food Chemistry, Volume 119, Issue 2, 15 March 2010, Pages 592-599.
47. Zhang Z, Knobloch TJ, Seamon LG et al. A black raspberry extract inhibits proliferation and regulates apoptosis in cervical cancer cells. Gynecologic Oncology, Volume 123, Issue 2, November 2011, Pages 401-406.

48. http://www.ars.usda.gov/main/site_main.htm?modecode=80-40-05-25

Black Pepper

pepper.png

1. Abila B, Richens A, Davies JA. Anticonvulsant effects of extracts of the west African black pepper, Piper guineense. J Ethnopharmacol 1993 Jun;39(2):113-7. 1993. PMID:16400.

2. http://www.ncbi.nlm.nih.gov/pubmed/25554982

3. http://www.whfoods.com/genpage.php?tname=foodspice&dbid=74#nutritionalprofile

4. http://www.ncbi.nlm.nih.gov/pubmed/25541091

5. Wood, Rebecca. The Whole Foods Encyclopedia. New York, NY: Prentice-Hall Press; 1988. 1988. PMID:15220.

6. http://www.ncbi.nlm.nih.gov/pubmed/25479727

7. Murray MT. The Healing Power of Foods. Prima Publishing, Rocklin, CA, 1993, pp. 211-212. 1993.

8. http://www.ncbi.nlm.nih.gov/pubmed/25446579

9. Mujumdar AM, Dhuley JN, Deshmukh VK, et al. Anti-inflammatory activity of piperine. Jpn J Med Sci Biol 1990 Jun;43(3):95-100. 1990. PMID:16380.

10. http://www.ncbi.nlm.nih.gov/pubmed/25444919

11. Fortin, Francois, Editorial Director. The Visual Foods Encyclopedia. Macmillan, New York. 1996.

12. http://www.ncbi.nlm.nih.gov/pubmed/25438036

13. Grieve M. A Modern Herbal. Dover Publications, New York. 1971.

14. http://www.ncbi.nlm.nih.gov/pubmed/25384161

15. Grieve M. A Modern Herbal. Dover Publications, New York. 1971.

16. http://www.ncbi.nlm.nih.gov/pubmed/25375334

17. Ensminger AH, Esminger M. K. J. e. al. Food for Health: A Nutrition Encyclopedia. Clovis, California: Pegus Press; 1986. 1986. PMID:15210.

18. http://www.ncbi.nlm.nih.gov/pubmed/25331343

19. Ensminger AH, Ensminger, ME, Kondale JE, Robson JRK. Foods & Nutriton Encyclopedia. Pegus Press, Clovis, California. 1983.

20. http://www.ncbi.nlm.nih.gov/pubmed/25327968

21. Dorman HJ, Deans SG. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol 2000 Feb;88(2):308-16. 2000. PMID:16390.

22. http://www.ncbi.nlm.nih.gov/pubmed/25173461

23. Calucci L, Pinzino C, Zandomeneghi M et al. Effects of gamma-irradiation on the free radical and antioxidant contents in nine aromatic herbs and spices. J Agric Food Chem 2003 Feb 12; 51(4):927-34. 2003.

24. http://www.ncbi.nlm.nih.gov/pubmed/25166889

25. Ao P, Hu S, Zhao A. [Essential oil analysis and trace element study of the roots of Piper nigrum L.]. Zhongguo Zhong Yao Za Zhi 1998 Jan;23(1):42-3, 63. 1998. PMID:16370.

26. http://www.ncbi.nlm.nih.gov/pubmed/25153972

27. Merck Index, 11th Edition, 7442

28. http://www.ncbi.nlm.nih.gov/pubmed/25141367

29. Epstein, William W.; Netz, David F.; Seidel, Jimmy L. (1993). "Isolation of piperine from black pepper". J. Chem. Ed. 70 (7): 598. doi:10.1021/ed070p598.

30. http://www.ncbi.nlm.nih.gov/pubmed/25119528

31. Oersted, "Über das Piperin, ein neues Pflanzenalkaloid" [On piperine, a new plant alkaloid], (Schweigger's) Journal für Chemie und Physik, vol. 29, no. 1, pages 80-82 (1820).

32. http://www.ncbi.nlm.nih.gov/pubmed/25050023

33. McNamara FN, Randall A, Gunthorpe MJ (March 2005). "Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1)". Br. J. Pharmacol. 144 (6): 781–90. doi:10.1038/sj.bjp.0706040. PMC 1576058. PMID 15685214.

34. http://www.ncbi.nlm.nih.gov/pubmed/25027570

35. Atal CK, Dubey RK, Singh J (January 1985). "Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism". J. Pharmacol. Exp. Ther. 232 (1): 258–62. PMID 3917507.

36. http://www.ncbi.nlm.nih.gov/pubmed/24835937

37. Bhardwaj RK, Glaeser H, Becquemont L, Klotz U, Gupta SK, Fromm MF (August 2002). "Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4". J. Pharmacol. Exp. Ther. 302 (2): 645–50. doi:10.1124/jpet.102.034728. PMID 12130727.

38. http://www.ncbi.nlm.nih.gov/pubmed/24819444

39. Srinivasan, K (2007). "Black pepper and its pungent principle-piperine: A review of diverse physiological effects". Critical Reviews in Food Science and Nutrition 47 (8): 735–48. doi:10.1080/10408390601062054. PMID 17987447.

40. http://www.ncbi.nlm.nih.gov/pubmed/24816193

41. Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS (May 1998). "Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers". Planta Med. 64 (4): 353–6. doi:10.1055/s-2006-957450. PMID 9619120.

42. http://www.ncbi.nlm.nih.gov/pubmed/24525095

43. Wattanathorna, Jintanaporn; Pennapa Chonpathompikunlertb; Supaporn Muchimapuraa; Aroonsri Pripremc; Orathai Tankamnerdthai (September 2008). "Piperine, the potential functional food for mood and cognitive disorders". Food and Chemical Toxicology 46 (9): 3106–3110. doi:10.1016/j.fct.2008.06.014. PMID 18639606.

44. http://www.ncbi.nlm.nih.gov/pubmed/24418140

45. Singh J, Dubey RK, Ata CK l (1986). "Piperine-mediated inhibition of glucuronidation activity in isolated epithelial cells of the guinea-pig small intestine: evidence that piperine lowers the endogeneous UDP-glucuronic acid content". Pharamcol. Exp. Ther. 236: 488–493.

46. http://www.ncbi.nlm.nih.gov/pubmed/24388894

47. Reen RK, Jamwal DS, Taneja SC, et al. (July 1993). "Impairment of UDP-glucose dehydrogenase and glucuronidation activities in liver and small intestine of rat and guinea pig in vitro by piperine". Biochem. Pharmacol. 46 (2): 229–38. doi:10.1016/0006-2952(93)90408-O. PMID 8347144.

48. http://www.ncbi.nlm.nih.gov/pubmed/24387754

49. Johnson, J. J.; Nihal, M; Siddiqui, I. A.; Scarlett, C. O.; Bailey, H. H.; Mukhtar, H; Ahmad, N (2011). "Enhancing the bioavailability of resveratrol by combining it with piperine". Molecular Nutrition & Food Research 55 (8): 1169–76. doi:10.1002/mnfr.201100117. PMC 3295233. PMID 21714124.

50. http://www.ncbi.nlm.nih.gov/pubmed/24370971

51. Faas, L.; Venkatasamy, R.; Hider, R. C.; Young, A. R.; Soumyanath, A. (2008). "In vivo evaluation of piperine and synthetic analogues as potential treatments for vitiligo using a sparsely pigmented mouse model". British Journal of Dermatology 158 (5): 941–50. doi:10.1111/j.1365-2133.2008.08464.x. PMID 18284389.

52. http://www.ncbi.nlm.nih.gov/pubmed/24348547

53. Ikan, Raphael (1991). Natural Products: A Laboratory Guide 2nd Ed.. San Diego: Academic Press, Inc. pp. 223–224. ISBN 0123705517.

54. http://www.ncbi.nlm.nih.gov/pubmed/24329956

57. http://www.tis-gdv.de/tis_e/ware/gewuerze/pfeffer/pfeffer.htm#selbsterhitzung

58. http://www.ncbi.nlm.nih.gov/pubmed/24250643

59. http://www.ncbi.nlm.nih.gov/pubmed/24005374

60. Majeed, M. Use of piperine as a bioavailability enhancer. US Patent 5744161, October 26, 1999.

61. http://www.ncbi.nlm.nih.gov/pubmed/23993499

62. http://www.ncbi.nlm.nih.gov/pubmed/23905652

63. http://www.ncbi.nlm.nih.gov/pubmed/23895150

64. Manoharan S, Balakrishnan S, Menon V, et al. Singapore Med J. 2009 Feb;50(2):139-46.

65. http://www.ncbi.nlm.nih.gov/pubmed/23886380

66. Bang JS, Oh DH, Choi HM, et al. Arthritis Res Ther. 2009 Mar 30;11(2):R49.

67. http://www.ncbi.nlm.nih.gov/pubmed/23868040

68. Doucette CD, Hilchie AL, Liwski R, Hoskin DW. J Nutr Biochem 2013;24:231-239.

69. http://nutritionfacts.org/2015/02/05/why-pepper-boosts-turmeric-blood-levels/

70. https://www.ncbi.nlm.nih.gov/pubmed/28545378

71. https://www.ncbi.nlm.nih.gov/pubmed/28641526

72. https://www.ncbi.nlm.nih.gov/pubmed/28669317

73. https://www.ncbi.nlm.nih.gov/pubmed/28671634

74. https://www.ncbi.nlm.nih.gov/pubmed/28680454

75. https://www.ncbi.nlm.nih.gov/pubmed/26273991

76. https://www.ncbi.nlm.nih.gov/pubmed/27905507

77. https://www.ncbi.nlm.nih.gov/pubmed/28699236

78. https://www.ncbi.nlm.nih.gov/pubmed/29176994

79. https://www.ncbi.nlm.nih.gov/pubmed/29226913

Turmeric

tumeric.png

1. Ammon, H.P. and M.A. Wahl. 1991. Pharmacology of Curcuma longa . Planta Med 57(1):1"“7
2. Ammon, H.P., M.I. Anazodo, H. Safayhi, B.N. Dhawan, R.C. Srimal. 1992. Curcumin: a potent inhibitor of leukotriene B4 formation in rat peritoneal polymorphonuclear neutrophils. Planta Med 58(2):226
3. Ayurvedic Pharmacopoeia of India (API). 1989. New Delhi: Government of India"”Ministry of Health and Family Welfare"”Department of Health. 45"“46
4. Baumann, J.C., K. Heintze, H.W. Muth. 1971. Klinisch-experimentelle untersuchungen der gallen-, pankreas- und magensaftsekretion unter den phytocholagogen wirkstoffen einer Carduus marianus "“Chelidonium "“Curcuma suspension [Clinico-experimental studies on the secretion of bile, pancreatic and gastric juice under the influence of phytocholagogous agents of a suspension of Carduus marianus, Chelidonium and Curcuma] Arzneimforsch 21(1):98"“101
5. Baumann, J.C. 1975. Ãœber die wirkung von Chelidonium , Curcuma , Absinth und Carduus marianus auf die galle-und pankreassekretion bei hepatopathien [Effect of Chelidonium , Curcuma , Absinth and Carduus marianus on the bile and pancreatic secretion in liver diseases]. Med Monatsschr 29(4):173"“180
6. Braun, R. et al. 1997. Standardzulassungen für Fertigarzneimittel"”Text and Kommentar . Stuttgart: Deutscher Apotheker Verlag
7. Budavari, S. (ed.). 1996. The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals , 12th ed. Whitehouse Station, N.J.: Merck & Co., Inc. 450, 1674
8. But, P.P.H. et al. (eds.). 1997. International Collation of Traditional and Folk Medicine . Singapore: World Scientific. 207"“208
9. Charles, V. and S.X. Charles. 1992. The use and efficacy of Azadirachta indica ADR ("˜Neem') and Curcuma longa ("˜Turmeric') in scabies. A pilot study. Trop Geogr Med 44(1"“2):178"“181
10. Gonda, R., M. Tomoda, K. Takada, N. Ohara, N. Shimizu. 1992. The core structure of ukonan A, a phagocytosis-activating polysaccharide from the rhizome of Curcuma longa , and immunological activities of degradation products. Chem Pharm Bull (Tokyo) 40(4):990"“993
11. Gonda, R., M. Tomoda, N. Ohara, K. Takada. 1993. Arabinogalactan core structure and immunological activities of ukonan C, an acidic polysaccharide from the rhizome of Curcuma longa . Biol Pharm Bull 16(3):235"“238
12. Hastak, K. et al. 1997. Effect of turmeric oil and turmeric oleoresin on cytogenetic damage in patients suffering from oral submucous fibrosis. Cancer Lett 116(2):265"“269
13. Iwu, M.M. 1993. Handbook of African Medicinal Plants . Boca Raton: CRC Press. 164"“166
14. The Japanese Standards for Herbal Medicines (JSHM). 1993. Tokyo: Yakuji Nippo, Ltd. 279
15. Kapoor, L.D. 1990. CRC Handbook of Ayurvedic Medicinal Plants. Boca Raton: CRC Press. 149"“150
16. Kiso, Y., Y. Suzuki, N. Watanabe, Y. Oshima, H. Hikino. 1983. Antihepatotoxic principles of Curcuma longa rhizomes. Planta Med 49(3):185"“187
17. Kiuchi, F. et al. 1993. Nematocidal activity of turmeric: synergistic action of curcuminoids. Chem Pharm Bull (Tokyo) 41(9):1640"“1643
18. Kositchaiwat, C., S. Kositchaiwat, J. Havanondha. 1993. Curcuma longa Linn. in the treatment of gastric ulcer comparison to liquid antacid: a controlled clinical trial. J Med Assoc Thai 76(11):601"“605
19. Leung, A.Y. and S. Foster. 1996. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics , 2nd ed. New York: John Wiley & Sons, Inc. 499"“501
20. McGuffin, M., C. Hobbs, R. Upton, A. Goldberg. 1997. American Herbal Product Association's Botanical Safety Handbook. Boca Raton: CRC Press. 39
21. Nadkarni, K.M. 1976. Indian Materia Medica . Bombay: Popular Prakashan. 414"“418
22. Polasa, K., T.C. Raghuram, T.P. Krishna, K. Krishnaswamy. 1992. Effect of turmeric on urinary mutagens in smokers. Mutagenesis 7(2):107"“109
23. Rao, C.V., A. Rivenson, B. Simi, B.S. Reddy. 1995. Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res 55(2):259"“266
24. Roth, G.N., A. Chandra, M.G. Nair. 1998. Novel bioactivities of Curcuma longa constituents. J Nat Prod 61(4):542"“545
25. Schulz, V., R. Hänsel, V.E. Tyler. 1998. Rational Phytotherapy: A Physicians' Guide to Herbal Medicine. New York: Springer
26. Selvam, R., L. Subramanian, R. Gayathri, N. Angayarkanni. 1995. The anti-oxidant activity of turmeric (Curcuma longa). J Ethnopharmacol 47(2):59"“67
27. Srinivas, L. and V.K. Shalini. 1991. DNA damage by smoke: protection by turmeric and other inhibitors of ROS. Free Radic Biol Med 11(3):277"“283
28. Srinivas, L., V.K. Shalini, M. Shylaja. 1992. Turmerin: a water-soluble antioxidant peptide from turmeric (Curcuma longa ). Arch Biochem Biophys 292(2):617"“623
29. Srivastava, K.C. 1989. Extracts from two frequently consumed spices"”cumin (Cucinum cyminum ) and turmeric (Curcuma longa )"”inhibit platelet aggregation and alter eicosanoid biosynthesis in human blood platelets
Prostaglandins Leukot Essent Fatty Acids 37(1):57"“64

30. Srivastava, R., M. Dikshit, R.C. Srimal, B.N. Dhawan. 1985. Anti-thrombotic effect of curcumin. Thrombosis Res 40(3):413"“417
31. Srivastava, R., V. Puri, R.C. Srimal, B.N. Dhawan. 1986. Effect of curcumin on platelet aggregation and vascular prostacyclin synthesis. Arzneimforsch 36(4):715"“717
32. Stansbury, J.E. 1999. Cancer prevention diet"”the potential of protective phytochemicals. Nutrition Science News 4(8):380"“386
33. Subramanian, M., M. Sreejayan, N. Rao, T.P. Devasagayam, B.B. Singh. 1994. Diminution of singlet oxygen-induced DNA damage by curcumin and related antioxidants. Mutat Res 311(2):249"“255
34. Thamlikitkul, V. et al. 1989. Randomized double blind study of Curcuma domestica Val. for dyspepsia. J Med Assoc Thai 72(11):613"“620
35. Tu, G. (ed.). 1992. Pharmacopoeia of the People's Republic of China (English Edition 1992). Beijing: Guangdong Science and Technology Press. 202"“203
36. Tyler, V.E. 1994. Herbs of Choice: The Therapeutic Use of Phytomedicinals . New York: Pharmaceutical Products Press
37. Yen, K.Y. 1992. The Illustrated Chinese Materia Medica"”Crude and Prepared. Taipei, Taiwan: SMC Publishing, Inc. 82
38. Ferreira, L.A. et al. 1992. Antivenom and biological effects of ar -turmerone isolated from Curcuma longa Toxicon 30(10):1211"“1218
39. Jentzsch, K., T. Gonda, H. Höller. 1959. Papierchromatographische Unterscheidung von Curcuma domestica Val. und Curcuma xanthorrhiza Roxb. Pharm Acta Helv 34(4):181"“188
40. Jiangsu Institute of Modern Medicine. 1977. Zhong Yao Da Ci Dian (Encyclopedia of Chinese Materia Medica), Vol. 3. Shanghai: Shanghai Scientific and Technical Publications
41. Leung, A.Y. 1984. Chinese Herbal Remedies . New York: Universe Books. [Republished as: Chinese Healing Foods and Herbs. 1993. Glen Rock: AYSL Corp.]
42. Qureshi, S., A.H. Shah, A.M. Ageel. 1992. Toxicity studies on Alpinia galanga and Curcuma longa . Planta Med 58(2):124"“127
43. Randhawa, G.S. and R.K. Mahey. 1988. Herbs, Spices, and Medicinal Plants: Recent Advances in Botany, Horticulture, and Pharmacology , Vol. 3. Phoenix: Oryx Press
44. Srimal, R.C. and B.N. Dhawan. 1973. Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J Pharm Pharmacol 25(6):447"“452
45. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781139/
46. http://www.vitasearch.com/get-clp-summary/40704
47. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781139
48. http://www.atherosclerosis-journal.com
49. http://dermatologistsblog.com/sunburns/topical-vesicular-formulations-of-curcuma-longa-extract-on-recuperating-the-uv-damaged-skin-author-interview/
50. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488238/
51. http://www.mdanderson.org/publications/cancerwise/archives/2008-september/cancerwise-september-2008-curcumin-temporarily-slows-pancreatic-cancer.html
52. http://www.hopkinsmedicine.org/neurology_neurosurgery/specialty_areas/pituitary_center/pituitary-tumor/types/pituitary-adenoma.html
53. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969660/
54. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969660/

Ginger

ginger.png

1. Fischer-Rasmussen W, Kjaer SK, Dahl C, Asping U. Ginger treatment of hyperemesis gravidarum. Eur J Obstet Gynecol Reprod Biol 1991;38:19"“24.
2. Borrelli F, Capasso R, Aviello G, et al. Effectiveness and safety of ginger in the treatment of pregnancy-induced nausea and vomiting. Obstet Gynecol 2005;105:849"“56.
3. Fulder S, Tenne M. Ginger as an anti-nausea remedy in pregnancy and the issue of safety. HerbalGram 1996;38:47"“50.
4. Mowrey DB, Clayson DE. Motion sickness, ginger, and psychophysics. Lancet 1982;1:655"“7.
5. Grontved A, Brask T, Kambskard J, et al. Ginger root against seasickness. Acta Otolaryngol 1988;105:45"“9.
6. Ribenfeld D, Borzone L. Randomized double-blind study comparing ginger (Zintona®) with dimenhydrinate in motion sickness. Healthnotes Rev Complementary Integrative Med 1999;6:98"“101.
7. Careddu P. Motion sickness in children: results of a double-blind study with ginger (Zintona®) and dimenhydrinate. Healthnotes Rev Complementary Integrative Med 1999;6:102"“7.
8. Stewart JJ, Wood MJ, Wood CD, Mims ME. Effects of ginger on motion sickness susceptibility and gastric function. Pharmacology 1991;42:111"“20.
9. Holtmann S, Clarke AH, Scherer H, et al. The anti-motion sickness mechanism of ginger. Acta Otolaryngol 1989;108:168"“74.
10. Grontved A, Hentzer E. Vertigo-reducing effect of ginger root. ORL 1986;48:282.
11. Srivastava KC, Mustafa T. Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hypotheses 1992;39:342"“8.
12. Bliddal H, Rosetzsky A, Schlichting P, et al. A randomized, placebo-controlled crossover study of ginger extracts and ibuprofen in osteoarthritis. Osteoarthritis Cartilage 2000;8:9"“12.
13. Altman RD, Marcussen KC. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum 2001;44:2531"“8.
14. Yarnell EY, Abascal K. An herbal formula for treating intractable epilepsy: a review of the literature. Alt Compl Ther 2000;6:203"“6 [review].
15. Narita Y, Satowa H, Kokubu T, et al. Treatment of epileptic patients with the Chinese herbal medicine "saiko-keishi-to" (SK). IRCS Med Sci 1982;10:88"“9.
16. Nagakubo S, Niwa S-I, Kumagai N, et al. Effects of TJ-960 on Sternberg's paradigm results in epileptic patients. Jpn J Psych Neur 1993;47:609"“19.
17. Hirayama C, Okumura M, Tanikawa K, et al. A multicenter randomized controlled clinical trial of Shosaiko-to in chronic active hepatitis. Gastroent Jap 1989;24:715"“9.
18. Fujiwara K, Ohta Y, Ogata I, et al. Treatment trial of traditional Oriental medicine in chronic viral hepatitis. In: Ohta Y (ed) New Trends in Peptic Ulcer and Chronic Hepatitis: Part II. Chronic Hepatitis. Tokyo: Excerpta Medica, 1987, 141"“6.
19. Tajiri H, Kozaiwa K, Osaki Y, et al. The study of the effect of sho-saiko-to on HBeAg clearance in children with chronic HBV infection and with abnormal liver function tests. Acta Paediatr Jpn 1991;94:1811"“5.
20. Gibo Y, Nakamura Y, Takahashi N, et al. Clinical study of sho-saiko-to therapy for Japanese patients with chronic hepatitis C (CH-C). Prog Med 1994;14:217"“9.
21. Gibo Y, Nakamura Y, Takahashi N, et al. Clinical study of sho-saiko-to therapy for Japanese patients with chronic hepatitis C (CH-C). Prog Med 1994;14:217"“9.
22. Oka H, Yamamoto S, Kuroki T, et al. Prospective study of chemoprevention of hepatocellular carcinoma with sho-saiko-to (TJ-9). Cancer 1995;76:743"“9.
23. Mizushima Y, Oosaki R, Kobayashi M. Clinical features of pneumonitis induced by herbal drugs. Phytother Res 1997;11:295"“8.
24. Forster HB, Niklas H, Lutz S. Antispasmodic effects of some medicinal plants. Planta Med 1980;40:303"“19.
25. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 425"“6.
26. Weiss RF. Herbal Medicine. Beaconsfield, UK: Beaconsfield Publishers Ltd, 1988, 185"“6.
27. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 198.
28. Micklefield GH, Redeker Y, Meister V, et al. Effects of ginger on gastroduodenal motility. Int J Clin Pharmacol Ther 1999;37:341"“6.
29. Yamamoto M, Oka H, Kanno T, et al. Controlled prospective trial to evaluate sho-saiko-to for the prevention of hepatotcellular carcinoma in patients with cirrhosis of the liver. Gan To Kagaku Ryoho (Jpn J Cancer Chemother) 1989;16:1519"“24 [in Japanese].
30. Norred CL, Zamudio S, Palmer SK. Use of complementary and alternative medicines by surgical patients. AANA J 2000;68:13"“8.
31. Murphy JM. Preoperative considerations with herbal medicines. AORN J 1999;69:173"“5, 177"“8, 180"“3.
32. Robb-Nicholson C. By the way, doctor. My surgeon advised me to stop taking gingko biloba before my hip surgery. Can you explain why? Are there any other herbs I should avoid? Harv Womens Health Watch 2000;7:8.
33. Phillips S, Ruggier R, Hutchinson SE. Zingiber officinale (ginger)"”an antiemetic for day case surgery. Anaesthesia 1993;48:715"“7.
34. Bone ME, Wilkinson DJ, Young JR, et al. Ginger root"”a new antiemetic. The effect of ginger root on the postoperative nausea and vomiting after major gynaecological surgery. Anaesthesia 1990;45:669"“71.
35. Visalyaputra S, Petchpaisit N, Somcharoen K, Choavaratana R. The efficacy of ginger root in the prevention of postoperative nausea and vomiting after outpatient gynaecological laparoscopy. Anaesthesia 1998;53:506"“10.
36. Arfeen Z, Owen H, Plummer JL, et al. A double-blind randomized controlled trial of ginger for the prevention of postoperative nausea and vomiting. Anaesth Intensive Care 1995;23:449"“52.
37. Ernst E, Pittler MH. Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. Br J Anaesth 2000;84:367"“71 [review].
38. Chaiyakunapruk N, Kitikannakorn N, Nathisuwan S, et al. The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis. Am J Obstet Gynecol2006;194:95"“9.
39. Grontved A, Hentzer E. Vertigo-reducing effect of ginger root. A controlled clinical study. ORL J Otorhinolaryngol Relat Spec 1986;48:282"“6.
40. Grontved A, Brask T, Kambskard J, Hentzer E. Ginger root against sea sickness. A controlled trial in the open sea. Acta Otolarygol 1988;105:45"“9.
41. Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc) and fenugreek (Trigonella foenumgraceum L) on blood lipids, blood sugar, and platelet aggregation in patients with coronary artery disease. Prostagland Leukotrienes Essential Fatty Acids 1997;56:379"“84.
42. Lumb AB. Effect of dried ginger on human platelet function. Thromb Haemost 1994;7:110"“1.
43. Janssen PL, Meyboom S, van Staveren WA, et al. Consumption of ginger (Zingiber officinale Roscoe) does not affect ex vivo platelet thromboxane production in humans. Eur J Clin Nutr 1996;50:772"“4.
44. Baba S, Takasaka T. Double-blind clinical trial of sho-seiryu-to (TJ-19) for perennial nasal allergy. Clin Otolaryngol 1995;88:389"“405.
45. Inada Y, Watanabe K, Kamiyama M, et al. In vitro immunomodulatory effects of traditional Kampo medicine (sho-saiko-to: SST) on peripheral mononuclear cells in patients with AIDS. Biomed Pharmacother 1990;44:17"“9.
46. Piras G, Makino M, Baba M. Sho-saiko-to, a traditional kampo medicine, enhances the anti-HIV-1 activity of lamivudine (3TC) in vitro. Microbiol Immunol 1997;41:435"“9.
47. Fujimaki M, Hada M, Ikematsu S, et al. Clinical efficacy of two kinds of kampo medicine on HIV infected patients. Int Conf AIDS 1989;5:400 [abstract no. W.B.P.292].
48. Li BQ, Fu T, Yan YD, et al. Inhibition of HIV infection by baicalin"”a flavonoid compound purified from Chinese herbal medicine. Cell Mol Biol Res 1993;39:119"“24.
49. Westphal J, Hörning M, Leonhardt K. Phytotherapy in functional abdominal complaints: Results of a clinical study with a preparation of several plants. Phytomedicine 1996;2:285"“91.
50. Mustafa T, Srivastava KC. Ginger (Zingiber officinale) in migraine headache. J Ethnopharmacol 1990;29:267"“73.
51. Srivastava KC, Mustafa T. Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hypoth 1992;39:342"“8.
52. Chopra A, Lavin P, Patwardhan B, Chitre D. Randomized double blind trial of an Ayurvedic plant derived formulation for treatment of rheumatoid arthritis. J Rheumatol 2000;27:1365"“72.
53. Tyler VE. Herbs of Choice: The Therapeutic Use of Phytomedicinals. Binghamton, NY: Pharmaceutical Products Press, 1994, 39"“42.
54. Holtmann S, Clarke AH, Scherer H, Hohn M. The anti-motion sickness mechanism of ginger. A comparative study with placebo and dimenhydrinate. Acta Otolaryngol (Stockh) 1989;108:168"“74.
55. Grontved A, Brask T, Kambskard J, Hentzer E. Ginger root against seasickness. Acta Otolaryngol 1988;105:45"“9.
56. Ribenfeld D, Borzone L. Randomized double-blind study comparing ginger (Zintona®) with dimenhydrinate in motion sickness. Healthnotes Rev Complementary Integrative Med 1999;6:98"“101.
57. Careddu P. Motion sickness in children: Results of a double-blind study with ginger (Zintona®) and dimenhydrinate. Healthnotes Rev Complementary Integrative Med 1999;6:102"“7.
58. Bone ME, Wilkinson DJ, Young JR, et al. Ginger root"”a new antiemetic: The effect of ginger root on postoperative nausea and vomiting after major gynaecological surgery. Anaesthesia 1990;45:669"“71.
59. Phillips S, Ruggier R, Hutchingson SE. Zingiber officinale (ginger)"”an antiemetic for day case surgery. Anaesthesia 1993;48:715"“7.
60. Arfeen Z, Owen H, Plummer JL, et al. A double-blind randomized controlled trial of ginger for the prevention of postoperative nausea and vomiting. Anaesthesia 1995;23:449"“52.
61. Meyer K, Schwartz J, Craer D, Keyes B. Zingiber officinale (ginger) used to prevent 8-Mop associated nausea. Dermatol Nursing 1995;7:242"“4.
62. Langner E, Greifenberg S, Gruenwald J. Ginger: History and use. Adv Ther 1998;15:25"“44 [review].
63. Bradley PR (ed). British Herbal Compendium, vol 1. Bournemouth, Dorset, UK: British Herbal Medicine Association, 1992, 112"“4.
64. Yamahara J, Huang QR, Li YH, et al. Gastrointestinal motility enhancing effect of ginger and its active constituents. Chem Pharm Bull 1990;38:430"“1.
65. al-Yahya MA, Rafatullah S, Mossa JS, et al. Gastroprotective activity of ginger in albino rats. Am J Chinese Med 1989;17:51"“6.
66. Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc) and fenugreek (Trigonella foenumgraecum L) on blood lipids, blood sugar, and platelet aggregation in patients with coronary artery disease. Prostagland Leukotrienes Essential Fatty Acids 1997;56:379"“84.
67. Verma SK, Singh J, Khamesra R, Bordia A. Effect of ginger on platelet aggregation in man. Indian J Med Res 1994;98:240"“2.

68. Lumb AB. Effect of dried ginger on human platelet function. Thromb Haemost 1994;7:110"“1.
69. Janssen PL, Meyboom S, van Staveren WA, et al. Consumption of ginger (Zingiber officinale Roscoe) does not affect ex vivo platelet thromboxane production in humans. Eur J Clin Nutr 1996;50:772"“4.
70. Brown DJ. Herbal Prescriptions for Better Health. Rocklin, CA: Prima Publishing, 1996, 111"“8.
71. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 135"“6.
72. Micklefield GH, Redeker Y, Meister V, et al. Effects of ginger on gastroduodenal motility. Int J Clin Pharmacol Ther 1999;37(7):341-6.
73. Phillips S, Ruggier R, Hutchinson SE. Zingiber officinale (ginger)-an antiemetic for day case surgery. Anaesthesia 1993;48(8):715-7.
74. Blumenthal M, editor. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
75. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
76. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
77. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
78. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
79. McGuffin M, et al, ed. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997.
80. Gruenwald J, et al. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
81. Schechter JO. Treatment of disequilibrium and nausea in the SRI discontinuation syndrome. J Clin Psychiatry 1998;59(8):431-2.
82. Fischer-Rasmussen W, Kjaer SK, Dahl C, Asping U. Ginger treatment of hyperemesis gravidarum. Eur J Obstet Gynecol Reprod Biol 1991;38(1):19-24.
83. Visalyaputra S, Petchpaisit N, Somcharoen K, Choavaratana R. The efficacy of ginger root in the prevention of postoperative nausea and vomiting after outpatient gynaecological laparoscopy. Anaesthesia 1998;53(5):506-10.
84. Bone ME, et al. Ginger root-a new antiemetic. The effect of ginger root on postoperative nausea and vomiting after major gynaecological surgery. Anaesthesia 1990;45(8):669-71.
85. Ernst E, Pittler MH. Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. Br J Anaesth 2000;84:367-71.
86. Anon. Case problem: presenting conventional and complementary approaches for relieving nausea in a breast cancer patient undergoing chemotherapy. J Am Diet Assoc 2000;100(2):257-9.
87. Wilkinson JM. What do we know about herbal morning sickness treatments? A literature survey. Midwifery 2000;16(3):224-8.
88. Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev 2000;(2):CD000145.
89. Lumb AB. Mechanism of antiemetic effect of ginger. Anaesthesia 1993;48(12):1118.
90. Arfeen Z, Owen H, Plummer JL, et al. A double-blind randomized controlled trial of ginger for the prevention of postoperative nausea and vomiting. Anaesth Intensive Care 1995;23(4):449-52.
91. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
92. "Zingiber officinale information from NPGS/GRIN". ars-grin.gov. Retrieved 3 March 2008.
93. "Spices: Exotic Flavors & Medicines: Ginger". Retrieved 8 August 2007.
94. "ginger". Online Etymology Dictionary, http://www.etymonline.com/. Retrieved 22 January 2011.
95. "Medicinal and Poisonous Plants of Southern and Eastern Africa" - Watt & Brandwijk
96. Ginger n Oxford Dictionary of English
97. "All about ginger at All Things Ginger". Allthingsginger.co.uk. Retrieved 25 April 2012.
98. Glorious Ginger: Root out Ailments with this Ancient Spice published by thefoodpaper.com
99. Antioxidant activity of a ginger extract published by [1]
100. "생강차 ginger tea 生薑茶" (in Korean). Doosan Encyclopedia. Retrieved 23 October 2009.
101. Identification of serotonin 5-HT1A receptor partial agonists in ginger. Nievergelt A. Huonker P. Schoop R. Altmann KH. Gertsch J. Bioorganic & Medicinal Chemistry. 18(9):3345-51, 2010 May 01
102. a b Ernst, E.; & Pittler, M.H. (1 March 2000). "Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials" (PDF). British Journal of Anesthesia 84 (3): 367"“371. PMID 10793599. Retrieved 6 September 2006.
103. Wood, C.; Pittler, MH (2000). "Comparison of efficacy of ginger with various antimotion sickness drugs". British journal of anaesthesia 84 (3): 367"“71. PMID 10793599.
104. Grøntved, A.; Pittler, MH (2000). "Ginger root against seasickness. A controlled trial on the open sea". British journal of anaesthesia 84 (3): 367"“71. PMID 10793599.
105. a b c University of Maryland Medical Centre (2006). "Ginger". Retrieved 2 August 2007.
106. Antiglycating potential of Zingiber officinalis and delay of diabetic cataract in rats. Saraswat M. Suryanarayana P. Reddy PY. Patil MA. Balakrishna N. Reddy GB. Molecular Vision. 16:1525"“37, 2010.
107. Al-Amin, Zainab M. et al.; Thomson, M; Al-Qattan, KK; Peltonen-Shalaby, R; Ali, M (2006). "Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats". British Journal of Nutrition (Cambridge University Press) 96 (4): 660"“666. doi:10.1079/BJN20061849. PMID 17010224. Retrieved 5 November 2007.
108. Afshari, Ali Taghizadeh et al.; Shirpoor, A; Farshid, A; Saadatian, R; Rasmi, Y; Saboory, E; Ilkhanizadeh, B; Allameh, A (2007). "The effect of ginger on diabetic nephropathy, plasma antioxidant capacity and lipid peroxidation in rats". Food Chemistry (Elsevier) 101 (1): 148"“153. doi:10.1016/j.foodchem.2006.01.013.
109. Chen, Jaw-Chyun; Li-Jiau Huang, Shih-Lu Wu, Sheng-Chu Kuo, Tin-Yun Ho, Chien-Yun Hsiang (2007). "Ginger and Its Bioactive Component Inhibit Enterotoxigenic Escherichia coli Heat-Labile Enterotoxin-Induced Diarrhoea in Mice". Journal of Agricultural and Food Chemistry 55 (21): 8390"“8397. doi:10.1021/jf071460f. PMID 17880155.
110. O'Hara, Mary; Kiefer, David; Farrell, Kim; Kemper, Kathi (1998). "A Review of 12 Commonly Used Medicinal Herbs". Archives of Family Medicine 7 (7): 523"“536. doi:10.1001/archfami.7.6.523. PMID 9821826.
111. Glorious Ginger: Root Out Ailments with This Ancient Spice published by thefoodpaper.com
112. Rhode, J.; Fogoros, S.; Zick, S.; Wahl, H.; Griffith, K. A.; Huang, J.; Liu, J. R. (2007). "Ginger inhibits cell growth and modulates angiogenic factors in ovarian cancer cells". BMC Complementary & Alternative Medicine 7: 44. doi:10.1186/1472-6882-7-44. PMC 2241638. PMID 18096028.
113. Kim, J. S.; et al., Sa Im; Park, Hye Won; Yang, Jae Heon; Shin, Tae-Yong; Kim, Youn-Chul; Baek, Nam-In; Kim, Sung-Hoon et al. (2008). "Cytotoxic components from the dried rhizomes of Zingiber officinale Roscoe". Archives of Pharmacal Research 31 (4): 415"“418. doi:10.1007/s12272-001-1172-y. PMID 18449496.
114. Choudhury, D.; et al., Amlan; Bhattacharya, Abhijit; Chakrabarti, Gopal (2010). "Aqueous extract of ginger shows antiproliferative activity through disruption of microtubule network of cancer cells". Food Chem Toxicol. 48 (10): 2872"“2880. doi:10.1016/j.fct.2010.07.020.
115. Oyagbemi, A. A.; Saba, A. B.; Azeez, O. I. (2010). "Molecular targets of [6]-gingerol: Its potential roles in cancer chemoprevention". Biofactors 36 (3): 169"“178. doi:10.1002/biof.78. PMID 20232343.

116. McGee, Harold (2004). On Food and Cooking: The Science and Lore of the Kitchen (2nd ed.). New York: Scribner. pp. 425"“426. ISBN 0-684-80001-2.
117. a b Al-Achi, Antoine. "A Current Look at Ginger Use". Retrieved 2 August 2007.
118. MDidea Extracts Professional (2010). "Dosage and Administration of Ginger". Retrieved 3 October 2010.
119. a b c Mayo Clinic (1 May 2006). "Drugs & Supplements: Ginger (Zingiber officinale Roscoe)". Retrieved 2 August 2007.
120. http://www.ncbi.nlm.nih.gov/pubmed/3537898
121. http://www.ncbi.nlm.nih.gov/pubmed/23123794
122. http://articles.mercola.com/sites/articles/archive/2014/06/30/ginger-health-benefits.aspx
123. http://www.ncbi.nlm.nih.gov/pubmed/15453957
124. http://www.ncbi.nlm.nih.gov/pubmed/22235230
125. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016669/?tool=pubmed
126. http://www.ncbi.nlm.nih.gov/pubmed/11710709
127. http://www.ncbi.nlm.nih.gov/pubmed/17695143
128. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519348/
129. http://www.ncbi.nlm.nih.gov/pubmed/17066513
130. http://www.ncbi.nlm.nih.gov/pubmed/21849094

131. http://www.ncbi.nlm.nih.gov/pubmed/23657930
132. http://www.ncbi.nlm.nih.gov/pubmed/19216660
133. http://www.ncbi.nlm.nih.gov/pubmed/6440548
134. http://www.academicjournals.org/article/article1380017545_Sebiomo%20et%20al.pdf
135. http://www.indianjrheumatol.com/article/S0973-3698%2810%2960514-6/abstract
136. http://www.ncbi.nlm.nih.gov/pubmed/20142827
137. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020385/?tool=pubmed
138. http://www.indianjrheumatol.com/article/S0973-3698(10)60514-6/abstract

 

Cinnamon

cinnamon.png

1. Braun, R. et al. 1997. Standardzulassungen für Fertigarzneimittel"”Text and Kommentar. Stuttgart: Deutscher Apotheker Verlag
2. British Herbal Pharmacopoeia (BHP). 1996. Exeter, U.K.: British Herbal Medicine Association
3. Bruneton, J. 1995. Pharmacognosy, Phytochemistry, Medicinal Plants. Paris: Lavoisier Publishing
4. Der Marderosian, A. (ed.). 1999. The Review of Natural Products. St. Louis: Facts and Comparisons
5. Europäisches Arzneibuch, 3rd ed. (Ph.Eur.3). 1997. Stuttgart: Deutscher Apotheker Verlag
6. Grieve, M. 1979. A Modern Herbal. New York: Dover Publications, Inc.
7. The Homeopathic Pharmacopoeia of the United States (HPUS). 1992. Revision Service Official Compendium. Boston: Pharmacopoeia Convention of the American Institute of Homeopathy
8. Karnick, C.R. 1994. Pharmacopoeial Standards of Herbal Plants, Vol. 1. Delhi: Sri Satguru Publications. 94"“95
9. Leung, A.Y. and S. Foster. 1996. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, 2nd ed. New York: John Wiley & Sons, Inc.
10. List, P.H. and L. Hörhammer (eds.). 1973. Hagers Handbuch der Pharmazeutischen Praxis, 4th ed. Vol. 4. New York: Springer Verlag. 54, 884
11. Hänsel, R., K. Keller, H. Rimpler, G. Schneider (eds.). 1992. Hagers Handbuch der Pharmazeutischen Praxis, 5th ed. Vol. 4. Berlin-Heidelberg: Springer Verlag. 884
12. McGuffin, M., C. Hobbs, R. Upton, A. Goldberg. 1997. American Herbal Product Association's Botanical Safety Handbook. Boca Raton: CRC Press
13. Newall, C.A., L.A. Anderson, J.D. Phillipson. 1996. Herbal Medicines: A Guide for Health-Care Professionals. London: The Pharmaceutical Press
14. Wichtl, M. and N.G. Bisset (eds.). 1994. Herbal Drugs and Phytopharmaceuticals. Stuttgart: Medpharm Scientific Publishers
15. Akira, T., S. Tanaka, M. Tabata. 1986. Pharmacological studies on the antiulcerogenic activity of Chinese cinnamon. Planta Med 52(6):440"“443
16. Azumi, S., A. Tanimura, K. Tanamoto. 1997. A novel inhibitor of bacterial endotoxin derived from cinnamon bark. Biochem Biophys Res Commun 234(2):506"“510
17. Braun, R. et al. 1997. Standardzulassungen für Fertigarzneimittel"”Text and Kommentar. Stuttgart: Deutscher Apotheker Verlag
18. British Herbal Pharmacopoeia (BHP). 1983. Keighley, U.K.: British Herbal Medicine Association
19. Bruneton, J. 1995. Pharmacognosy, Phytochemistry, Medicinal Plants. Paris: Lavoisier Publishing
20. Chang, H.M. and P.P.H. But (eds.) 1986. Pharmacology and Applications of Chinese Materia Medica. Philadelphia: World Scientific. 510"“514
21. Grieve, M. 1979. A Modern Herbal. New York: Dover Publications, Inc.
22. Hänsel, R., K. Keller, H. Rimpler, G. Schneider (eds.). 1992. Hagers Handbuch der Pharmazeutischen Praxis, 5th ed. Vol. 4. Berlin-Heidelberg: Springer Verlag
23. Hikino, H. 1985. Oriental Medicinal Plants. In: Wagner, H., H. Hikino, N.R. Farnsworth. 1985. Economic and Medicinal Plant Research, Vol. 1. London: Academic Press. 69"“70
24. Leung, A.Y. and S. Foster. 1996. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, 2nd ed. New York: John Wiley & Sons, Inc.
25. List, P.H. and L. Hörhammer (eds.). 1973. Hagers Handbuch der Pharmazeutischen Praxis, Vol. 4. New York: Springer Verlag. 54, 884
26. McGuffin, M., C. Hobbs, R. Upton, A. Goldberg. 1997. American Herbal Product Association's Botanical Safety Handbook. Boca Raton: CRC Press
27. Nadkarni, K.M. 1976. Indian Materia Medica. Bombay: Popular Prakashan. 328"“330
28. Newall, C.A., L.A. Anderson, J.D. Phillipson. 1996. Herbal Medicines: A Guide for Health-Care Professionals. London: The Pharmaceutical Press
29. Tu, G. (ed.). 1992. Pharmacopoeia of the People's Republic of China (English Edition 1992). Beijing: Guangdong Science and Technology Press. 31
30. Tyler, V.E., L.R. Brady, J.E. Robbers. 1988. Pharmacognosy , 9th ed. Philadelphia: Lea & Febiger. 119"“122
31. Yen, K.Y. 1992. The Illustrated Chinese Materia Medica"”Crude and Prepared. Taipei: SMC Publishing, Inc.
32. http://www.rush.edu/webapps/MEDREL/servlet/NewsRelease?id=1768
33. http://www.ibtimes.co.in/cinnamon-may-help-treat-parkinsons-disease-study-604144
34. Zhongshan Medical College Editorial Group (ZMC). 1975. Clinical Application of Chinese Traditional Drugs, 1st ed. Guangdong: Guangdong People's Publishing House. 8, 201

Broccoli

broccoli.png

1. "Broccoli May Help Protect Against Respiratory Conditions Like Asthma". Nursing Today. Mar 1 2009; ISSN 1940-6975.
2. Y Zhang, et al. (1992) A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure, Proc. Natl Acad. Sci., 89:2399"“2403 .
3. Angier, Natalie (1992-03-15). "Potent Chemical To Fight Cancer Seen in Broccoli - The". New York Times. Retrieved 2009-11-16.
4. P. Talalay, et al. (1997) Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens, Proc. Natl. Acad. Sci., 94:1036710372.
5. Angier, Natalie (1997-09-16). "Researchers Find a Concentrated Anticancer Substance in Broccoli Sprouts - The". New York Times. Retrieved 2009-11-16.
6. Rungapamestry et al. British Journal of Nutrition (2007), 97;644"“652.
7. Kensler et al. Cancer Epidemiol Biomarkers Prev 2005;14(11).
8. Cancer Epidemiology, Biomarkers Prevention, 2005; 14(11).
9. Yang, YM; Jhanwar-Uniyal, M; Schwartz, J; Conaway, CC; Halicka, HD; Traganos, F; Chung, FL (2006). "N-acetylcysteine conjugate of phenethyl isothiocyanate enhances apoptosis in growth-stimulated human lung cells". Cancer Research 65 (18): 8538"“8547. doi:10.1158/0008-5472.CAN-05-0236. PMID 16166335.
10. Proc. Natl. Acad. Sci. USA, 2002, 99(11):7610"“7615.
11. Cancer Epidemiology, Biomarkers & Prevention, 2005, 14(11.2): 2754s.
12. Cancer Epidemiology, Biomarkers & Prevention, 2005, 14(11).
13. Cancer Letters, 2006, 240:243"“252.
14. Cancer Research, 2006, 66:8293"“8296.
15. Proc. Natl. Acad. Sci., USA, 2007, 104(44):17500-5.
16. Cancer Research, 2003, 63:3980"“3986.
17. Carcinogenesis, 2004, 25:219"“227.
18. Carcinogenesis, 2007, 28(7):1485"“1490.
19. Cancer Epidemiology, Biomarkers & Prevention, 2001, Vol. 10, pp. 949"“954.
20. Carcinogenesis, 2004, 25:83"“90.
21. BMC Cancer, 2006, 6:62.
22. Proceedings of the American Association for Cancer Research, 2000; 41:660.
23. J. Nutrition, 2005, 135: 1865"“1872.
24. Cancer Chemother. Pharm., 2006, 57:317"“327.
25. Journal of the National Cancer Institute, 1999, 91(7):605"“613.
26. J. Nutrition, 2004, 134:2004"“2010.
27. Mol. Cancer Ther., 2006, 5(4):935"“944.
28. Cancer Research, 2008, 68(5):1593"“1600.
29. Cancer Research, 2001, 61(16): 6120"“6130.
30. Current Cancer Drug Targets, 2006, 6:135"“145.
32. Life Science, 2006; 78(26):3043"“3050.
33. Biofactors, 2004, 22:271"“275.
34. Proc. Natl. Acad. Sci. USA, 2004, 101(18):7094"“7099.
35. Proc. Natl. Acad. Sci. USA, 2001, 98(26):15221"“15226.
36. Proc. Natl. Acad. Sci. USA, 2004, 101( 28): 10446-10451.
37. Invest. Opthamol. Vis. Sci., 2005, 46: 979"“987.
38. Am J Resp Crit Care Med, 2008, 178(6):592"“604.
39. Diabetes, 2008, 57:2809"“2817.
40. European Journal of Clinical Nutrition, 2011, http://www.nature.com/ejcn/journal/vaop/ncurrent/full/ejcn201159a.html.
41. Guidance For Industry: Reducing Microbial Food Safety Hazards For Sprouted Seeds [1].
42. J.W. Fahey, et al. (2006) Pathogen detection, testing, and control in fresh broccoli sprouts, Nutritional Journal, retrieved Dec. 2008.
43. "Nutrition Journal | Full text | Pathogen detection, testing, and control in fresh broccoli sprouts". Nutritionj.com. Retrieved 2009-11-16.
44. http://science.naturalnews.com 48. Ambrosone CB, Tang L. Cruciferous vegetable intake and cancer prevention: role of nutrigenetics. Cancer Prev Res (Phila Pa). 2009 Apr;2(4):298-300. 2009.
45. Angeloni C, Leoncini E, Malaguti M, et al. Modulation of phase II enzymes by sulforaphane: implications for its cardioprotective potential. J Agric Food Chem. 2009 Jun 24;57(12):5615-22. 2009.
46. Banerjee S, Wang Z, Kong D, et al. 3,3'-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer. 3,3'-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer. 2009.
47. Bhattacharya A, Tang L, Li Y, et al. Inhibition of bladder cancer development by allyl isothiocyanate. Carcinogenesis. 2010 Feb;31(2):281-6. 2010.
48. Bryant CS, Kumar S, Chamala S, et al. Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells. Molecular Cancer 2010, 9:47. 2010.
49. Carpenter CL, Yu MC, and London SJ. Dietary isothiocyanates, glutathione S-transferase M1 (GSTM1), and lung cancer risk in African Americans and Caucasians from Los Angeles County, California. Nutr Cancer. 2009;61(4):492-9. 2009.
50. Christopher B, Sanjeez K, Sreedhar C, et al. Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells. Molecular Cancer Year: 2010 Vol: 9 Issue: 1 Pages/record No.: 47. 2010.
51. Chuanphongpanich S, Phanichphant S, Bhuddasukh D et al. Bioactive glucosinolates and antioxidant properties of broccoli seeds cultivated in Thailand. Songklanakarin Journal of Science and Technology Year: 2006 Vol: 28 Issue: Suppl.1 Pages/record No.: 55-61. 2006.
52. Clarke JD, Dashwood RH, Ho E. Multi-targeted prevention of cancer by sulforaphane. Cancer Lett. 2008 Oct 8;269(2):291-304. 2008.
53. Cornelis MC, El-Sohemy A, Campos H. GSTT1 genotype modifies the association between cruciferous vegetable intake and the risk of myocardial infarction. Am J Clin Nutr. 2007 Sep;86(3):752-8. 2007.
54. Higdon JV, Delage B, Williams DE, et al. Cruciferous Vegetables and Human Cancer Risk: Epidemiologic Evidence and Mechanistic Basis. Pharmacol Res. 2007 March; 55(3): 224-236. 2007.
55. Ho E, Clarke JD, Dashwood RH. Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention. J Nutr. 2009 Dec;139(12):2393-6. 2009.

56. Hofmann T, Kuhnert A, Schubert A et al. Modulation of detoxification enzymes by watercress: in vitro and in vivo investigations in human peripheral blood cells. Eur J Nutr. 2009 Dec;48(8):483-91. 2009.
57. Hu J, Straub J, Xiao D, et al. Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1. Cancer Res. 2007 Apr 15;67(8):3569-73. 2007.
58. Hutzen B, Willis W, Jones S, et al. Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells. Cancer Cell International 2009, 9:24. 2009.
59. Jiang H, Shang X, Wu H, et al. Combination treatment with resveratrol and sulforaphane induces apoptosis in human U251 glioma cells. Neurochem Res. 2010 Jan;35(1):152-61. 2010.
60. Kahlon TS, Chiu MC, and Chapman MH. Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage. Nutr Res. 2008 Jun;28(6):351-7. 2008.
61. Konsue N, Ioannides C. Modulation of carcinogen-metabolising cytochromes P450 in human liver by the chemopreventive phytochemical phenethyl isothiocyanate, a constituent of cruciferous vegetables. Toxicology. 2010 Feb 9;268(3):184-90. 2010.
62. Kunimasa K, Kobayashi T, Kaji K et al. Antiangiogenic effects of indole-3-carbinol and 3,3'-diindolylmethane are associated with their differential regulation of ERK1/2 and Akt in tube-forming HUVEC. J Nutr. 2010 Jan;140(1):1-6. 2010.
63. Lakhan SE, Kirchgessner A, Hofer M. Inflammatory mechanisms in ischemic stroke: therapeutic approaches. Journal of Translational Medicine 2009, 7:97. 2009.
64. Larsson SC, Andersson SO, Johansson JE, et al. Fruit and vegetable consumption and risk of bladder cancer: a prospective cohort study. Cancer Epidemiol Biomarkers Prev. 2008 Sep;17(9):2519-22. 2008.
65. Li F, Hullar MAJ, Schwarz Y, et al. Human Gut Bacterial Communities Are Altered by Addition of Cruciferous Vegetables to a Controlled Fruit- and Vegetable-Free Diet. Journal of Nutrition, Vol. 139, No. 9, 1685-1691, September 2009. 2009.
66. Lin J, Kamat A, Gu J, et al. Dietary intake of vegetables and fruits and the modification effects of GSTM1 and NAT2 genotypes on bladder cancer risk. Cancer Epidemiol Biomarkers Prev. 2009 Jul;18(7):2090-7. 2009.
67. Machijima Y, Ishikawa C, Sawada S, et al. Anti-adult T-cell leukemia/lymphoma effects of indole-3-carbinol. Retrovirology 2009, 6:7. 2009.
68. Nakamura Y, Yogosawa S, Izutani Y et al. A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy. Mol Cancer. 2009 Nov 12;8:100. 2009.
69. Navarro SL, Chang JL, Peterson S et al. Modulation of human serum glutathione S-transferase A1/2 concentration by cruciferous vegetables in a controlled feeding study is influenced by GSTM1 and GSTT1 genotypes. Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):2974-8. 2009.
70. Nettleton JA, Steffen LM, Mayer-Davis EJ, et al. Dietary patterns are associated with biochemical markers of inflammation and endothelial activation in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Clin Nutr. 2006 Jun;83(6):1369-79. 2006.
71. Pellegrini N, Chiavaro E, Gardana C et al. Effect of Different Cooking Methods on Color, Phytochemical Concentration, and Antioxidant Capacity of Raw and Frozen Brassica Vegetables. J. Agric. Food Chem., 2010, 58 (7), pp 4310-4321. 2010.
72. Prawan A, Saw CL, Khor TO, et al. Anti-NF-kappaB and anti-inflammatory activities of synthetic isothiocyanates: effect of chemical structures and cellular signaling. Chem Biol Interact. 2009 May 15;179(2-3):202-11. 2009.
73. Rungapamestry V, Duncan AJ, Fuller Z et al. Effect of cooking brassica vegetables on the subsequent hydrolysis and metabolic fate of glucosinolates. Proc Nutr Soc. 2007 Feb;66(1):69-81. 2007.
74. Silberstein JL, Parsons JK. Evidence-based principles of bladder cancer and diet. Urology. 2010 Feb;75(2):340-6. 2010.
75. Steinbrecher A, Linseisen J. Dietary Intake of Individual Glucosinolates in Participants of the EPIC-Heidelberg Cohort Study. Ann Nutr Metab 2009;54:87-96. 2009.
76. Tang L, Zirpoli GR, Guru K et al. Consumption of Raw Cruciferous Vegetables is Inversely Associated with Bladder Cancer Risk. Cancer Res. 2007 Apr 15;67(8):3569-73. 2007.
77. Taraseviien Z, Danilenko E, Jarien E et al. Changes in Some Chemical Components During Germination of Broccoli Seeds. Notulae Botanicae Horti Agrobotanici Cluj-Napoca Year: 2009 Vol: 37 Issue: 2 Pages/record No.: 173-176. 2009.
78. Tarozzi A, Morroni F, Merlicco A, et al. Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line. J Neurochem. 2009 Dec;111(5):1161-71. 2009.
79. Thompson CA, Habermann TM, Wang AH, et al. Antioxidant intake from fruits, vegetables and other sources and risk of non-Hodgkin's lymphoma: the Iowa Women's Health Study. Int J Cancer. 2010 Feb 15;126(4):992-1003. 2010.
80. Traka M, Gasper AV, Melchini A et al. Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate. PLoS One. 2008 Jul 2;3(7):e2568. 2008.
81. Vasanthi HR, Mukherjee S and Das DK. Potential health benefits of broccoli- a chemico-biological overview. Mini Rev Med Chem. 2009 Jun;9(6):749-59. 2009.
82. Vivar OI, Saunier EF, Leitman DC et al. Selective activation of estrogen receptor-{beta} target genes by 3,3'-diindolylmethane. Endocrinology. 2010 Apr;151(4):1662-7. 2010.
83. Yanaka A, Fahey JW, Fukumoto A et al. Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans. Cancer Prev Res (Phila Pa). 2009 Apr;2(4):353-60. 2009.
84. Yang G, Gao YT, Shu XO et al. Isothiocyanate exposure, glutathione S-transferase polymorphisms, and colorectal cancer risk. Am J Clin Nutr. 2010 Mar;91(3):704-11. 2010.
85. Zhang Y. Allyl isothiocyanate as a cancer chemopreventive phytochemical. Mol Nutr Food Res. 2010 Jan;54(1):127-35. 2010.
86. Zhu H, Jia Z, Zhou K et al. Cruciferous dithiolethione-mediated coordinated induction of total cellular and mitochondrial antioxidants and phase 2 enzymes in human primary cardiomyocytes: cytoprotection against oxidative/electr. Exp Biol Med (Maywood). 2009 Apr;234(4):418-29. 2009.

Broccoli Sprouts

broc sprouts.png

1. "Broccoli May Help Protect Against Respiratory Conditions Like Asthma". Nursing Today. Mar 1 2009; ISSN 1940-6975.
2. Y Zhang, et al. (1992) A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure, Proc. Natl Acad. Sci., 89:2399"“2403 .
3. Angier, Natalie (1992-03-15). "Potent Chemical To Fight Cancer Seen in Broccoli - The". New York Times. Retrieved 2009-11-16.
4. P. Talalay, et al. (1997) Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens, Proc. Natl. Acad. Sci., 94:1036710372.
5. Angier, Natalie (1997-09-16). "Researchers Find a Concentrated Anticancer Substance in Broccoli Sprouts - The". New York Times. Retrieved 2009-11-16.
6. Nutrient Data Laboratory.
7. Rungapamestry et al. British Journal of Nutrition (2007), 97;644"“652.
8. Kensler et al. Cancer Epidemiol Biomarkers Prev 2005;14(11).
9. Cancer Epidemiology, Biomarkers Prevention, 2005; 14(11).
10. Yang, YM; Jhanwar-Uniyal, M; Schwartz, J; Conaway, CC; Halicka, HD; Traganos, F; Chung, FL (2006). "N-acetylcysteine conjugate of phenethyl isothiocyanate enhances apoptosis in growth-stimulated human lung cells". Cancer Research 65 (18): 8538"“8547. doi:10.1158/0008-5472.CAN-05-0236. PMID 16166335.
11. Proc. Natl. Acad. Sci. USA, 2002, 99(11):7610"“7615.
12. Cancer Epidemiology, Biomarkers & Prevention, 2005, 14(11.2): 2754s.
13. Cancer Epidemiology, Biomarkers & Prevention, 2005, 14(11).
14. Cancer Letters, 2006, 240:243"“252.
15. Cancer Research, 2006, 66:8293"“8296.
16. Proc. Natl. Acad. Sci., USA, 2007, 104(44):17500-5.
17. Cancer Research, 2003, 63:3980"“3986.
18. Carcinogenesis, 2004, 25:219"“227.
19. Carcinogenesis, 2007, 28(7):1485"“1490.
20. Cancer Epidemiology, Biomarkers & Prevention, 2001, Vol. 10, pp. 949"“954.
21. Carcinogenesis, 2004, 25:83"“90.
22. BMC Cancer, 2006, 6:62.
23. Proceedings of the American Association for Cancer Research, 2000; 41:660.
24. J. Nutrition, 2005, 135: 1865"“1872.
25. Cancer Chemother. Pharm., 2006, 57:317"“327.
26. Journal of the National Cancer Institute, 1999, 91(7):605"“613.
27. J. Nutrition, 2004, 134:2004"“2010.
28. Mol. Cancer Ther., 2006, 5(4):935"“944.
29. Cancer Research, 2008, 68(5):1593"“1600.
30. Cancer Research, 2001, 61(16): 6120"“6130.
31. Current Cancer Drug Targets, 2006, 6:135"“145.
32. Life Science, 2006; 78(26):3043"“3050.
33. Biofactors, 2004, 22:271"“275.
34. Proc. Natl. Acad. Sci. USA, 2004, 101(18):7094"“7099.
35. Proc. Natl. Acad. Sci. USA, 2001, 98(26):15221"“15226.
36. Proc. Natl. Acad. Sci. USA, 2004, 101( 28): 10446-10451.
37. Invest. Opthamol. Vis. Sci., 2005, 46: 979"“987.
38. Am J Resp Crit Care Med, 2008, 178(6):592"“604.
39. Diabetes, 2008, 57:2809"“2817.
40. European Journal of Clinical Nutrition, 2011, http://www.nature.com/ejcn/journal/vaop/ncurrent/full/ejcn201159a.html.
41. Guidance For Industry: Reducing Microbial Food Safety Hazards For Sprouted Seeds [1].
42. J.W. Fahey, et al. (2006) Pathogen detection, testing, and control in fresh broccoli sprouts, Nutritional Journal, retrieved Dec. 2008.
43. "Nutrition Journal | Full text | Pathogen detection, testing, and control in fresh broccoli sprouts". Nutritionj.com. Retrieved 2009-11-16.
44. http://news.ifr.ac.uk
45. http://www.ibtimes.com
46. http://www.nutraingredients.com
47. http://science.naturalnews.com 48. Ambrosone CB, Tang L. Cruciferous vegetable intake and cancer prevention: role of nutrigenetics. Cancer Prev Res (Phila Pa). 2009 Apr;2(4):298-300. 2009.
48. Angeloni C, Leoncini E, Malaguti M, et al. Modulation of phase II enzymes by sulforaphane: implications for its cardioprotective potential. J Agric Food Chem. 2009 Jun 24;57(12):5615-22. 2009.
49. Banerjee S, Wang Z, Kong D, et al. 3,3'-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer. 3,3'-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer. 2009.
50. Bhattacharya A, Tang L, Li Y, et al. Inhibition of bladder cancer development by allyl isothiocyanate. Carcinogenesis. 2010 Feb;31(2):281-6. 2010.
51. Bryant CS, Kumar S, Chamala S, et al. Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells. Molecular Cancer 2010, 9:47. 2010.
52. Carpenter CL, Yu MC, and London SJ. Dietary isothiocyanates, glutathione S-transferase M1 (GSTM1), and lung cancer risk in African Americans and Caucasians from Los Angeles County, California. Nutr Cancer. 2009;61(4):492-9. 2009.
53. Christopher B, Sanjeez K, Sreedhar C, et al. Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells. Molecular Cancer Year: 2010 Vol: 9 Issue: 1 Pages/record No.: 47. 2010.
54. Chuanphongpanich S, Phanichphant S, Bhuddasukh D et al. Bioactive glucosinolates and antioxidant properties of broccoli seeds cultivated in Thailand. Songklanakarin Journal of Science and Technology Year: 2006 Vol: 28 Issue: Suppl.1 Pages/record No.: 55-61. 2006.
55. Clarke JD, Dashwood RH, Ho E. Multi-targeted prevention of cancer by sulforaphane. Cancer Lett. 2008 Oct 8;269(2):291-304. 2008.
56. Cornelis MC, El-Sohemy A, Campos H. GSTT1 genotype modifies the association between cruciferous vegetable intake and the risk of myocardial infarction. Am J Clin Nutr. 2007 Sep;86(3):752-8. 2007.
57. Higdon JV, Delage B, Williams DE, et al. Cruciferous Vegetables and Human Cancer Risk: Epidemiologic Evidence and Mechanistic Basis. Pharmacol Res. 2007 March; 55(3): 224-236. 2007.
58. Ho E, Clarke JD, Dashwood RH. Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention. J Nutr. 2009 Dec;139(12):2393-6. 2009.
59. Hofmann T, Kuhnert A, Schubert A et al. Modulation of detoxification enzymes by watercress: in vitro and in vivo investigations in human peripheral blood cells. Eur J Nutr. 2009 Dec;48(8):483-91. 2009.
60. Hu J, Straub J, Xiao D, et al. Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1. Cancer Res. 2007 Apr 15;67(8):3569-73. 2007.
61. Hutzen B, Willis W, Jones S, et al. Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells. Cancer Cell International 2009, 9:24. 2009.
62. Jiang H, Shang X, Wu H, et al. Combination treatment with resveratrol and sulforaphane induces apoptosis in human U251 glioma cells. Neurochem Res. 2010 Jan;35(1):152-61. 2010.
63. Kahlon TS, Chiu MC, and Chapman MH. Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage. Nutr Res. 2008 Jun;28(6):351-7. 2008.
64. Konsue N, Ioannides C. Modulation of carcinogen-metabolising cytochromes P450 in human liver by the chemopreventive phytochemical phenethyl isothiocyanate, a constituent of cruciferous vegetables. Toxicology. 2010 Feb 9;268(3):184-90. 2010.
65. Kunimasa K, Kobayashi T, Kaji K et al. Antiangiogenic effects of indole-3-carbinol and 3,3'-diindolylmethane are associated with their differential regulation of ERK1/2 and Akt in tube-forming HUVEC. J Nutr. 2010 Jan;140(1):1-6. 2010.
66. Lakhan SE, Kirchgessner A, Hofer M. Inflammatory mechanisms in ischemic stroke: therapeutic approaches. Journal of Translational Medicine 2009, 7:97. 2009.
67. Larsson SC, Andersson SO, Johansson JE, et al. Fruit and vegetable consumption and risk of bladder cancer: a prospective cohort study. Cancer Epidemiol Biomarkers Prev. 2008 Sep;17(9):2519-22. 2008.
68. Li F, Hullar MAJ, Schwarz Y, et al. Human Gut Bacterial Communities Are Altered by Addition of Cruciferous Vegetables to a Controlled Fruit- and Vegetable-Free Diet. Journal of Nutrition, Vol. 139, No. 9, 1685-1691, September 2009. 2009.
69. Lin J, Kamat A, Gu J, et al. Dietary intake of vegetables and fruits and the modification effects of GSTM1 and NAT2 genotypes on bladder cancer risk. Cancer Epidemiol Biomarkers Prev. 2009 Jul;18(7):2090-7. 2009.
70. Machijima Y, Ishikawa C, Sawada S, et al. Anti-adult T-cell leukemia/lymphoma effects of indole-3-carbinol. Retrovirology 2009, 6:7. 2009.
71. Nakamura Y, Yogosawa S, Izutani Y et al. A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy. Mol Cancer. 2009 Nov 12;8:100. 2009.
72. Navarro SL, Chang JL, Peterson S et al. Modulation of human serum glutathione S-transferase A1/2 concentration by cruciferous vegetables in a controlled feeding study is influenced by GSTM1 and GSTT1 genotypes. Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):2974-8. 2009.
73. Nettleton JA, Steffen LM, Mayer-Davis EJ, et al. Dietary patterns are associated with biochemical markers of inflammation and endothelial activation in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Clin Nutr. 2006 Jun;83(6):1369-79. 2006.
74. Pellegrini N, Chiavaro E, Gardana C et al. Effect of Different Cooking Methods on Color, Phytochemical Concentration, and Antioxidant Capacity of Raw and Frozen Brassica Vegetables. J. Agric. Food Chem., 2010, 58 (7), pp 4310-4321. 2010.
75. Prawan A, Saw CL, Khor TO, et al. Anti-NF-kappaB and anti-inflammatory activities of synthetic isothiocyanates: effect of chemical structures and cellular signaling. Chem Biol Interact. 2009 May 15;179(2-3):202-11. 2009.
76. Rungapamestry V, Duncan AJ, Fuller Z et al. Effect of cooking brassica vegetables on the subsequent hydrolysis and metabolic fate of glucosinolates. Proc Nutr Soc. 2007 Feb;66(1):69-81. 2007.
77. Silberstein JL, Parsons JK. Evidence-based principles of bladder cancer and diet. Urology. 2010 Feb;75(2):340-6. 2010.
78. Steinbrecher A, Linseisen J. Dietary Intake of Individual Glucosinolates in Participants of the EPIC-Heidelberg Cohort Study. Ann Nutr Metab 2009;54:87-96. 2009.
79. Tang L, Zirpoli GR, Guru K et al. Consumption of Raw Cruciferous Vegetables is Inversely Associated with Bladder Cancer Risk. Cancer Res. 2007 Apr 15;67(8):3569-73. 2007.
80. Taraseviien Z, Danilenko E, Jarien E et al. Changes in Some Chemical Components During Germination of Broccoli Seeds. Notulae Botanicae Horti Agrobotanici Cluj-Napoca Year: 2009 Vol: 37 Issue: 2 Pages/record No.: 173-176. 2009.
81. Tarozzi A, Morroni F, Merlicco A, et al. Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line. J Neurochem. 2009 Dec;111(5):1161-71. 2009.
82. Thompson CA, Habermann TM, Wang AH, et al. Antioxidant intake from fruits, vegetables and other sources and risk of non-Hodgkin's lymphoma: the Iowa Women's Health Study. Int J Cancer. 2010 Feb 15;126(4):992-1003. 2010.
83. Traka M, Gasper AV, Melchini A et al. Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate. PLoS One. 2008 Jul 2;3(7):e2568. 2008.
84. Vasanthi HR, Mukherjee S and Das DK. Potential health benefits of broccoli- a chemico-biological overview. Mini Rev Med Chem. 2009 Jun;9(6):749-59. 2009.
85. Vivar OI, Saunier EF, Leitman DC et al. Selective activation of estrogen receptor-{beta} target genes by 3,3'-diindolylmethane. Endocrinology. 2010 Apr;151(4):1662-7. 2010.
86. Yanaka A, Fahey JW, Fukumoto A et al. Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans. Cancer Prev Res (Phila Pa). 2009 Apr;2(4):353-60. 2009.
87. Yang G, Gao YT, Shu XO et al. Isothiocyanate exposure, glutathione S-transferase polymorphisms, and colorectal cancer risk. Am J Clin Nutr. 2010 Mar;91(3):704-11. 2010.
88. Zhang Y. Allyl isothiocyanate as a cancer chemopreventive phytochemical. Mol Nutr Food Res. 2010 Jan;54(1):127-35. 2010.
89. Zhu H, Jia Z, Zhou K et al. Cruciferous dithiolethione-mediated coordinated induction of total cellular and mitochondrial antioxidants and phase 2 enzymes in human primary cardiomyocytes: cytoprotection against oxidative/electr. Exp Biol Med (Maywood). 2009 Apr;234(4):418-29. 2009.
90. http://www.ncbi.nlm.nih.gov/pubmed/23983046
91. http://preventdisease.com/news/13/082913_Broccoli-Based-Medicine-Against-Cancer-Osteoporosis-and-Cardiovascular-Protection.shtml
92. http://time.com/#2891178/broccoli-sprout-beverage-can-detoxify-pollutants/
93. http://cancerpreventionresearch.aacrjournals.org/content/early/2014/06/07/1940-6207.CAPR-14-0103.abstract
94. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC23369/
95. http://www.hopkinsmedicine.org/press/1997/sept/970903.htm
96. http://www.ncbi.nlm.nih.gov/pubmed/22052072
97. http://www.pnas.org/content/94/21/11149.full
98. http://www.hopkinsmedicine.org/press/1997/sept/970903.htm
99. http://www.nature.com/scitable/topicpage/the-role-of-methylation-in-gene-expression-1070

Lingonberry

1.Oana-Crina Buior, Christian Ginies, Valentin I. Popa, Claire Dufour, et al. Phenolic Compounds and Antioxidant activity of Lingonberry (Vaccinium vitus-idaea L.) leaf, stem and fruit at different harvest periods. Food Chemistry. 2018; 252:356-365

2. Törrönen R, Kolehmainen M, Sarkkinen E, Poutanen K, Mykkänen H, Niskanen L. Berries reduce postprandial insulin responses to wheat and rye breads in healthy women. J Nutr. 2013 Apr;143(4):430-6. doi: 10.3945/jn.112.169771. Epub 2013 Jan 30.

3.Törrönen R, Kolehmainen M, Sarkkinen E, Mykkänen H, Niskanen L. Postprandial glucose, insulin, and free fatty acid responses to sucrose consumed with blackcurrants and lingonberries in healthy women. Am J Clin Nutr. 2012 Sep;96(3):527-33. doi: 10.3945/ajcn.112.042184. Epub 2012 Aug 1.

4. Riitta Törrönen, Marjukka Kolehmainen, Essi Sarkkinen, Hannu Mykkänen, Leo Niskanen, Postprandial glucose, insulin, and free fatty acid responses to sucrose consumed with blackcurrants and lingonberries in healthy women, The American Journal of Clinical Nutrition, Volume 96, Issue 3, September 2012, Pages 527–533, https://doi.org/10.3945/ajcn.112.042184

5. Quek R, Henry CJ. Influence of polyphenols from lingonberry, cranberry, and red grape on in vitro digestibility of rice. Int J Food Sci Nutr. 2015;66(4):378-82. doi: 10.3109/09637486.2015.1042849. Epub 2015 May 26. PMID: 26008717.

6. Chiok M, Satora P, Skotniczny M, Semik-Szczurak D, et al. Charactarisation of Antimicrobial Properties of Extracts of Selected Medicinal Plants. Polish Journal of Microbiology. 2017; Dec. 66(4): 463-472

7.Fu Z, Liska D, Talan D, Chung M. Cranberry Reduces the Risk of Urinary Tract Infection Recurrence in Otherwise Healthy Women: A Systematic Review and Meta-Analysis. J Nutr. 2017 Dec;147(12):2282-2288. doi: 10.3945/jn.117.254961. Epub 2017 Oct 18. PMID: 29046404.

8. Davidson E, Zimmermann BF, Jungfer E, Chrubasik-Hausmann S. Prevention of urinary tract infections with vaccinium products. Phytother Res. 2014 Mar;28(3):465-70. doi: 10.1002/ptr.5047. Epub 2013 Aug 6. PMID: 23922238.

9.Wojnicz D, Kucharska AZ, Sokół-Łętowska A, Kicia M, Tichaczek-Goska D. Medicinal plants extracts affect virulence factors expression and biofilm formation by the uropathogenic Escherichia coli. Urol Res. 2012 Dec;40(6):683-97. doi: 10.1007/s00240-012-0499-6. Epub 2012 Aug 23. PMID: 22915095; PMCID: PMC3495101.

10. Tapiainen T, Jauhiainen H, Jaakola L, Salo J, Sevander J, Ikäheimo I, Pirttilä AM, Hohtola A, Uhari M. Biofilm formation and virulence of uropathogenic Escherichia coli in urine after consumption of cranberry-lingonberry juice. Eur J Clin Microbiol Infect Dis. 2012 May;31(5):655-62. doi: 10.1007/s10096-011-1355-2. Epub 2011 Aug 7. PMID: 21822564.

11. Nikolaeva-Glomb L, Mukova L, Nikolova N, Badjakov I, Dincheva I, Kondakova V, Doumanova L, Galabov AS. In vitro antiviral activity of a series of wild berry fruit extracts against representatives of Picorna-, Orthomyxo- and Paramyxoviridae. Nat Prod Commun. 2014 Jan;9(1):51-4. PMID: 24660461.

12. Nilsson A, Salo I, Plaza M, Björck I. Effects of a mixed berry beverage on cognitive functions and cardiometabolic risk markers; A randomized cross-over study in healthy older adults. PLoS One. 2017 Nov 15;12(11):e0188173. doi: 10.1371/journal.pone.0188173. eCollection 2017.

13. Nilsson A, Salo I, Plaza M, Björck I. Effects of a mixed berry beverage on cognitive functions and cardiometabolic risk markers; A randomized cross-over study in healthy older adults. PLoS One. 2017 Nov 15;12(11):e0188173. doi: 10.1371/journal.pone.0188173. PMID: 29141041; PMCID: PMC5687726.

14. Zuo C, Li W, Wang L, Zhu J, Wang L, Wang Z. [Effects of lingonberry extraction on the mice cognitive function damaged by chronic stress]. Wei Sheng Yan Jiu. 2015 Nov;44(6):943-8. Chinese. PMID: 26738388

15. Bhullar KS, Rupasinghe HPV. Partridgeberry polyphenols protect primary cortical and hippocampal neurons against β-amyloid toxicity. Food Res Int. 2015 Aug;74:237-249. doi: 10.1016/j.foodres.2015.05.019. Epub 2015 May 11. PMID: 28411989

16. Bhullar KS, Rupasinghe HP. Partridgeberry polyphenols protect rat primary cortical neurons from oxygen-glucose deprivation-reperfusion-induced injury via suppression of inflammatory adipokines and regulation of HIF-1α and PPARγ. Nutr Neurosci. 2016 Jul;19(6):260-8. doi: 10.1179/1476830515Y.0000000026. Epub 2015 May 5. PMID: 25941748

17. Isaak CK, Petkau JC, Blewett H, O K, Siow YL. Lingonberry anthocyanins protect cardiac cells from oxidative-stress-induced apoptosis. Can J Physiol Pharmacol. 2017 Aug;95(8):904-910. doi: 10.1139/cjpp-2016-0667. Epub 2017 Apr 6. PMID: 28384410

18. Isaak CK, Wang P, Prashar S, O K, Brown DC, Debnath SC, Siow YL. Supplementing diet with Manitoba lingonberry juice reduces kidney ischemia-reperfusion injury. J Sci Food Agric. 2017 Jul;97(9):3065-3076. doi: 10.1002/jsfa.8200. Epub 2017 Feb 6. PMID: 28074603

19. Pärnänen P, Nawaz A, Sorsa T, Meurman J, Nikula-Ijäs P. The Effect of Fermented Lingonberry Juice on Candida glabrata Intracellular Protein Expression. Int J Dent. 2017;2017:6185395. doi: 10.1155/2017/6185395. Epub 2017 Mar 30. PMID: 28465686; PMCID: PMC5390647

20.Heyman-Lindén L, Kotowska D, Sand E, et al. Lingonberries alter the gut microbiota and prevent low-grade inflammation in high-fat diet fed mice. Food Nutr Res. 2016;60:29993. Published 2016 Apr 27. doi:10.3402/fnr.v60.29993

21.Matziouridou C, Marungruang N, Nguyen TD, Nyman M, Fåk F. Lingonberries reduce atherosclerosis in Apoe(-/-) mice in association with altered gut microbiota composition and improved lipid profile. Mol Nutr Food Res. 2016 May;60(5):1150-60. doi: 10.1002/mnfr.201500738. Epub 2016 Mar 22. PMID: 26890232

22. Ogawa K, Kuse Y, Tsuruma K, Kobayashi S, Shimazawa M, Hara H. Protective effects of bilberry and lingonberry extracts against blue light-emitting diode light-induced retinal photoreceptor cell damage in vitro. BMC Complement Altern Med. 2014 Apr 2;14:120. doi: 10.1186/1472-6882-14-120. PMID: 24690313; PMCID: PMC3992157

23. Eriksson NE, Möller C, Werner S, Magnusson J, Bengtsson U, Zolubas M. Self-reported food hypersensitivity in Sweden, Denmark, Estonia, Lithuania, and Russia. J Investig Allergol Clin Immunol. 2004;14(1):70-9. PMID: 15160445

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Bilberry

1. Canter PH, Ernst E. Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision--a systematic review of placebo-controlled trials. Surv Ophthalmol. 2004 Jan-Feb;49(1):38-50. doi: 10.1016/j.survophthal.2003.10.006. PMID: 1471143

2. Bagchi D, Roy S, Patel V, et al. Safety and whole body antioxidant potential of a novel anthocyanin-rich formula of edible berries. Mol Cell Biochem. 2006;281:197–209.

3. Bagchi D, Sen C.K, Bagchi M, Atalay M. Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyaninin-rich berry extract formula. Biochem (Moscow). 2004;69:75–80.

4. Bao L, Abe K, Tsang P, Xu J.K, Yao X.S, Liu H.W, Kurihara H. Bilberry extract protect restraint stress-induced liver damage through attenuating mitochondrial dysfunction. Fitoterapia. Jul 8, 2010. 2010. e doi:10​.1016/j.fitote.2010.07.004.pub.

5. Barringer T.A, Hatcher L, Sasser H.C. Potential benefits on impairment of endothelial function after a high-fat meal of 4 weeks of flavonoid supplementation. Evid Based Complement Alternat Med. 2008;10:1–6. [PMC free article]

6. Bertuglia S, Malandrino S, Colantuoni A. Effect of Vaccinium myrtillis anthocyanosides on ischaemic reperfusion injury in hamster cheek pouch microcirculation. Pharmacol Res. 1995;31:183–7.

7. Bravetti G.O, Fraboni E, Maccolini E. Preventive medical treatment of senile cataract with vitamin E and Vaccinium myrtillus anthocyanosides: Clinical evaluation. Ann Ottalmol Clin Ocul. 1989;115:109–16.

8. Burdulis D, Sarkinas A, Jasutienè I, Stackivicenè E, Nikolajevas L, Janulis V. Comparative study of anthocyanin composition, antimicrobial and antioxidant activity in bilberry ( Vaccinium myrtillus L.) and blueberry ( Vaccinium corymbosum L.) fruits. Acta Pol Pharm. 2009;66:399–408.

9. Camire M.E. Herbs Botanicals and Teas. Lancaster, PA: Technomic Publishing Company; 2000. Bilberries and blueberries as functional foods and nutraceuticals; pp. 289–319.

10. Canter P.H, Ernst E. Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision-a systematic review of placebo-controlled trials. Surv Ophthalmol. 2004;49:38–50.

11. Chatterjee A, Yasmin T, Bagchi D, Stohs S.J. Inhibition of Helicobacter pylori in vitro by various berry extracts, with enhanced susceptibility to clarithromycin. Mol Cell Biochem. 2004;265:19–26.

12.  Chen J, Uto T, Tanigawa S, Kumamoto T, Fuji M, Hou D.X. Expression profiling of genes targeted by bilberry (Vaccinium myrtillus) in macrophages through DNA array. Nutr Cancer. 2008;60:43–50.

13. Choi E.H, Ok H.E, Yoon Y, Magnuson B.A, Kim M.K, Chun H.S. Protective effect of anthocyanin-rich extract from bilberry ( Vaccinium myrtillus L.) against myelotoxicity induced by 5-fluorouracil. Biofactors. 2007;29:55–65.

14. Choi E.H, Park J.H, Kim M.K, Chun H.S. Alleviation of doxorubicin-induced toxicities by anthocyanin-rich bilberry ( Vaccinium myrtillus L.) extract in rats and mice. Biofactors. 2010 2010 July 7;36:319–27. Epub.

15. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: A comparison with clofibrate. Thromb Res. 1996;84:311–22.

16. Clifford M.N. Anthocyanins—nature, occurrence and dietary burden. J Sci Food Agric. 2000;80:1063–72.

17. Cooke D, Schwartz M, Boocock D, Winterhalter P, Steward W.P, Gescher A.J, Marczylo T.H. Effect of cyanidin-3-glucoseide andan anthocyanin mixture on adenoma development in the ApcMin mouse model of intestinal carcinogenesis—relationship with tissue anthocyanin levels. Int J Cancer. 2006;119:2213–20.

18. Cravotto G, Boffa L, Genzini L, Garella D. Phytotherapeutics: An evaluation of the potential of 1000 plants. J Clin Pharm Ther. 2010;35:11–48.

19. Detre Z, Jellinek H, Miskulin M, Robert A.M. Studies on vascular permeability in hypertension: Action of anthocyanosides. Clin Physiol Biochem. 1986;4:143–9.

20. Dreiseitel A, Schreier P, Oehme A, et al., editors. Inhibition of proteasome activity by anthocyanins and anthocyanidins. Biochem Biophys Res Commun. 2008;372:57–61.

21. Duthie S. Berry phytochemicals, genomic stability and cancer: Evidence for chemoprevention at several stages in the carcinogenic processes. Mol Nutr Food Res. 2007;52:386–7.

22. Erlund I, Kol R, Alfthan G, et al., editors. Favourable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr. 2008;87:323–31.

23. Erlund I, Marniemi J, Hakala P, Alfthan G, Meririnne E, Aro A. Consumption of blackcurrants, lingonberries and bilberries increases serum quercetin concentrations. Eur J Clin Nutr. 2003;57:37–42.

24. Ghosh D, Konishi T. Anthocyanins and anthocyanin-rich extracts: Role in diabetes and eye function. Asia Pac J Clin Nutr. 2007;16:200–8.

25. Grace M.H, Ribnicky D.M, Kuhn P, et al., editors. Hypoglycaemic activity of a novel anthocyanin-rich formulation from low-bush blueberry, Vaccinium anustifolium Aiton. Phytomedicine. 2009 2009 March 20;16:406–15. Epub. 

26. Helmstädter A, Schuster N. Vaccinium myrtillus as an antidiabetic medicinal plant-research through the ages. Pharmazie. 2010;65:315–21.

27. Hou D.-X. Potential mechanism of cancer chemoprevention by anthocyanins. Curr Mol Med. 2003;3:149–59. http://www​.ukwildflowers.com/ (accessed June 4th 2010)

28. Huttunen S, Toivanen M, Arkko S, Ruponen M, Tikkanen-Kaukanen C. Inhibition activity of wild berry juice fractions against Streptococcus pneumoniae binding to human bronchial cells. Phytother Res. 2010. n/a. doi: 10.1002/ptr.3240.

29. Jang Y.P, Zhou J, Nakanishi K, Sparrow J.R. Anthocyanins protect against photooxidation and membrane permeabilization in retinal pigment epithelial cells. Photochem Photobiol. 2005;81:529–36.

30. Jayaprakasam B, Vareed S.K, Olsen L.K, Nair M.G. Insulin secretion by bioactive anthocyanins and anthocyanins present in fruits. J Agric Food Chem. 2005;53:28–31.

31. Karlsen A, Paur I, Bøhn S.V, et al., editors. Bilberry juice modulates plasma concentration of NF-κB related inflammatory markers in subjects at increased risk of CVD. Eur J Nutr. 2010 2010 February 2;49:345–55. Epub.

32. Karlsen A, Retterstol L, Laake P, Paur I, Kjolsrud-Bohn S, Sandvik L, Blomhoff R. Anthocyanins inhibit nuclear factor-B activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults. J Nutr. 2007;137:1951–4.

33. Katsube N, Iwashita K, Tsuchida T, Yamaki K, Kobori M. Induction of apoptosis in cancer cells by bilberry ( Vaccinium myrtillus ) and the anthocyanins. J Agric Food Chem. 2003;51:68–75.

34. Kim Y.S, Young M.R, Bobe G, Colburn N.H, Milner J.A. Bioactive food components, inflammatory targets and cancer prevention. Cancer Prev Res. 2009;2:200–8.

35. Kolosova N.G, Shcheglova T.V, Sergeeva S.V, Loskutova L.V. Long term antioxidant supplementationattenuates oxidative stress markers and cognitive deficits in senescent-accelerated OXYS rats. Neurobiol Aging. 2006;27:1289–97.

36. Kong J.-M, Chia L.-S, Goh N.-K, Chia T.-F, Brouillard R. Analysis and biological activities of anthocyanins. Phytochem. 2003;64:923–33.

37. Kowalczyk C, Kxzesmski P, Kura M, Szmigiel B, Blaszczyk J. Anthocyanins in medicine. Pol J Pharmacol. 2003;55:699–702.

38. Lala G, Malik M, Zhao C, He J, Kwon Y, Giusti M.M, Magnuson B.A. Anthocyanin-rich extracts inhibit multiple biomarkers of colon cancer in rats. Nutr Cancer. 2006;54:84–93.

39. Lazzé M.C, Pizzaa R, Savio M, Stivala L.A, Prosperi E, Bianchi L. Anthocyanins protect against DNA damage induced by tert-butyl-hydroperoxide in rat smooth muscle and hepatoma cells. Mutat Res. 2003;535:103–15.

40. Lee S.W. Effects of bilberry ingestion on biomarkers of health and antioxidant content. MSc Thesis. Hong Kong: The Hong Kong Polytechnic University; 2008.

41. Lee M.H, Kwon H.A, Kwon D.Y, et al., editors. Antibacterial activity of medicinal herb extracts against Salmonella. Int J Food Microbiol. 2006;111:270–5.

42. Lee J, Lee H.K, Kim C.Y, Choe C.M, You T.W, Seong G.J. Purified high-dose anthocyanoside oligomer administration improves nocturnal vision and clinical symptoms in myopia subjects. Br J Nutr. 2005;93:895–9.

43. Madhavi D.L, Bomser J, Smith M. A. L, Singleton K. Isolation of bioactive constituents of Vaccinium myrtillis (bilberry) fruits and cell cultures. Plant Sci. 1998;131:95–103.

44. Martineau L.C, Couture A, Spoor D, et al., editors. Anti-diabetic properties of the Canadian low-bush blueberry Vaccinium angustifolium Ait. Phytomedicine. 2006;13:612–23.

45. Mas T, Susperregui J, Berkè B, Chéze C, Moreau S, Nuhrich A, Vercauteren J. DNA triplex stabilization property of natural anthocyanins. Phytochem. 2000;53:679–87.

46. Matsui T, Ogunwande I.A, Abesundara K.J, Matsumoto K. Anti-hyperglycemic potential of natural products. Mini Rev Med Chem. 2006;6:349–56.

47. Matsunaga N, Imai S, Inokuchi Y, Shimazawa M, Yokata S, Araki Y, Hara H. Bilberry and its main constituents have neuroprotective effects against retinal neuronal damage in vitro and in vivo. Mol Nutr Food Res. 2009;53:869–77. [PubMed]

48. Matsunaga N, Tsuruma K, Shimazawa M, Yokota S, Hara H. Inhibitory actions of bilberry anthycyanidins on angiogenesis. Phytother Res. 2010;24:S42–7.

49. Mazza G, Kay C.D, Correll T, Holub B.J. Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. J Agric Food Chem. 2002;50:7731–7.

50. McDougall G.J, Kulkarni N.N, Stewart D. Current developments on the inhibitory effects of berry polyphenols on digestive enzymes. Biofactors. 2008;34:73–80.

51. Milbury P.E, Graf B, Curran-Celentano J.M, Blumberg J.M. Bilberry (Vaccinium myrtillus) anthocyanins modulate heme oxygenase-1 and glutathione S-tranferase-pi expression in ARPE-19 cells. Invest Ophthalmol Vis Sci. 2007;48:2343–9.

52. Mutanen M, Pajari A.M, Paivarinta E, Misikangas M, Rajakangas J, Marttinen M, Oikarinen S. Berries as preventive dietary constituents-a mechanistic approach with ApcMin+ mouse. Asia Pac J Clin Nutr. 2008;17:123–5.

53. Nguyen V, Tang J, Oroudjev E, Lee C.J, Marasigan C, Wilson L, Ayoub G. Cytotoxic effects of bilberry extract in MCF7-GFP-tubulin breast cancer cells. J Med Food. 2010;13:278–85.

54. Packer L, Cadenas E. Oxidants and antioxidants revisited: New concepts of oxidative stress. Free Radic Res. 2007;41:951–2.

55. Park S.J, Shin W.H, Seo J.W, Kim E.J. Anthocyanins inhibit airway inflammation and hyper-responsiveness in a murine asthma model. Food Chem Toxicol. 2007;45:1459–67.

56. Persson I.A, Persson K, Andersson R.G. Effect of Vaccinium myrtillus and its polyphenols on angiotensin-converting enzyme activity in human endothelial cells. J Agric Food Chem. 2009;57:4626–9.

57. Petlevski R, Hadžija M, Slijepčević M, Juretic D. Effect of “antidiabetis” herbal preparation on serum glucose and fructosamine in NOD mice. J Ethnopharmacol. 2001;75:181–4.

58. Pool-Zobel B.L, Bub A, Schràder N, Rechkemmer G. Anthocyanins are potent antioxidants in model systems but do not reduce endogenous oxidative DNA damage in colon cells. Eur J Nutr. 1999;227-34;38

59. Prior R.L, Wu X. Anthocyanins: Structural characteristics that results in unique metabolic patterns and biological activities. Free Radic Res. 2006;40:1014–28.

60. Puupponen-Pimiä R, Nohynek L, Alakomi H.-L, Oksman-Caldentey K.-M. Bioactive berry compounds-novel tools against human pathogens. Appl Microbiol Biotechnol. 2005a;67:8–19.

61. Puupponen-Pimià R, Nohynek L, Alakomi H.-L, Oksman-Caldentey K.-M. Theaction of berry phenolics against human intestinal pathogens. Biofactors. 2005b;23:243–51.

62. Qin Y, Xia M, Ma J, et al., editors. Anthocyanin supplementation improves serum LDL- and HDL-cholesterol concentrations associated with the inhibition of cholesteryl ester transfer protein in dyslipidemic subjects. Am J Clin Nutr. 2009;90:485–92.

63. Saija A, Princi P, D’Amico N, Pasquale R. De, Costa G. Vaccinium myrtillus anthocyanins on triiodothyronine transport into the brain in the rat. Pharmacol Res. 1990;22:59–60.

64. Sakakibari H, Ogawa T, Koyanagi A, et al., editors. Distribution and excretion of bilberry anthocyanins in mice. J Agric Food Chem. 2009;57:7681–6.

65. Seeram N.P. Berry fruits: Compositional elements, biochemical activities, and the impact of their intake on human health, performance, and disease. J Agric Food Chem. 2008;56:627–9.

66. Seeram N.P. Berry fruits for cancer prevention: Current status and future prospects. J Agric Food Chem. 2009;56:630–5.

67. Sharma A.D, Sharma R. Anthocyanin-DNA copigmentation complex: Mutual protection against oxidative damage. Phytochem. 1999;52:1313–8.

68. Shukitt-Hale B, Lau F.C, Joseph J.A. Berry fruit supplementation and the aging brain. J Agric Food Chem. 2009;56:636–41.

69. Song J, Li Y, Ge J, et al., editors. Protective effects of bilberry ( Vaccinium myrtillis L.) extracts on cultured human corneal limbal epithelial cells (HCLEC). PhytotherRes. 2010;24:520–4.

70. Svobodová A, Zdarilová A, Vostalova J. Locinere caerulea and Vaccinium myrtillus fruit polyphenols protect HaCaT keratinocytes against UVB-induced phototoxic stress and DNA damage. J Dermatol Sci. 2009;56:196–201.

71. Takikawa M, Inoue S, Horio F, Tsuda T. Dietary anthocyaninrich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice. J Nutr. 2009;140:527–33.

72. Talavera S, Felgines C, Texier O, Besson C, Gil-Izquierdo A, Lamaison J.L, Remesy C. Anthocyanin metabolism in rats and their distribution to digestive area, kidney and brain. J Agric Food Chem. 2005;53:3902–8.

73. Talavera S, Felgines C, Texier O, Besson C, Lamaison J.L, Remesy C. Anthocyanins are efficiently absorbed from the stomach in anaesthetized rats. J Nutr. 2003;133:4178–82.

74. Thomasset S, Berry D.P, Cai H, et al., editors. Pilot study of oral anthocyanins for colorectal cancer chemoprevention. Cancer Prev Res. 2009;2:625–33.

75. Thomasset S, Teller N, Cai H, Marko D, Berry D.P, Steward W.P, Gescher A.J. Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs? Cancer Chemother Pharmacol. 2009;64:201–11.

76.Tsuda T. Regulation of adipocyte function by anthocyanins: Possibility of preventing the metabolic syndrome. J Agric Food Chem. 2008;56:642–6.

77. Tsuda T, Ueno Y, Kojo H, Yoshikawa T 3, Osawa T. Gene expression profile of isolated rat adipocytes treated with anthocyanins. Biochim Biophys Acta. 2005;1733:137–47.

78. Upton R, editor. Bilberry Fruit Vaccinium myrtillus L. Standards of Analysis, Quality Control, and Therapeutics. Santa Cruz, CA: American Herbal Pharmacopoeia and Therapeutic Compendium; 2001.

79. Valentova K, Ulrichova J, Cvak L, Simanek V. Cytoprotective effect of a bilberry extract against oxidative damage of rat hepatocytes. Food Chem. 2006;101:912–7.

80. Wang L.-S, Stoner G.D. Anthocyanins and their role in cancer prevention. Cancer Lett. 2008;269:281–90. [PMC free article]

81. National Institutes of Health, U.S. National Library of Medicine. 2010. “Bilberry.” www​.nlm.nih.gov/medlineplus​/druginfo/natural​/patient-bilberry.html

82. Yildirim H.K. Evaluation of colour parameters and antioxidant activities of fruit wine. Int J Food Sci Nutr. 2006;57:47–63.

83. Yoshida K, Mori M, Kondo T. Blue color development by anthocyanins: From chemical structure to cell physiology. Nat Prod Rep. 2009;26:884–915.

84. Zafra-Stone S, Taharat Y, Bagchi M, Chatterjee A, Vinson J.A, Bagchi D. Berry anthocyanins as novel antioxidants in human health and disease prevention. Mol Nutr Food Res. 2007;51:675–83.

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Monkfruit

1. Swingle, WT. Momrodica grosvenori Sp. Nov. the source of the Chinese Lo han kuo. J Arnold Arboretum. 1941;22:197-203. Department of Horticulture and Landscape Architecture. Purdue University. West Lafayette, IN.
2. Tsang KY, Ng TB. Isolation and characterization of a new ribosome inactivating protein, momorgrosvin, from seeds of the monk's fruit Momordica grosvenorii. Life Sci. 2001;68:773-784.
3. Hossen MA, Shinmei Y, Jiang S, et al. Effect of Lo Han Kuo (Siraitia grosvenori Swingle) on nasal rubbing and scratching behavior in ICR mice. Biol Pharm Bull. 2005;28:238-241.
4. Chen JC, Chiu MH, Nie RL, Cordell GA, Qiu SX. Cucurbitacins and cucurbitane glycosides: structures and biological activities. Nat Prod Rep. 2005;22:386-399.
5. Hussain RA, Lin YM, Poveda LJ, et al. Plant-derived sweetening agents: saccharide and polyol constituents of some sweet-tasting plants. J Ethnopharmacol. 1990;28:103-115.
6. Kinghorn AD. Biologically active compounds from plants with reputed medicinal and sweetening properties. J Nat Prod. 1987;50:1009-1024.
7. Jakinovich W Jr, Moon C, Choi YH, Kinghorn AD. Evaluation of plant extracts for sweetness using the Mongolian gerbil. J Nat Prod. 1990;53:190-195.
8. Vasquez E, Jakinovich W Jr. Stimulation of the gerbil's gustatory receptors by some potently sweet terpenoids. J Agric Food Chem. 1993;41:1305-1310.
9. Suzuki YA, Murata Y, Inui H, Sugiura M, Nakano Y. Triterpene glycosides of Siraitia grosvenori inhibit rat intestinal maltase and suppress the rise in blood glucose level after a single oral administration of maltose in rats. J Agric Food Chem. 2005;53:2941-2946.
10. Takeo E, Yoshida H, Tada N, et al. Sweet elements of Siraitia grosvenori inhibit oxidative modification of low-density lipoprotein. J Atheroscler Thromb. 2002;9:114-120.
11. Ukiya M, Akihisa T, Tokuda H, et al. Inhibitory effects of cucurbitane glycosides and other triterpenoids from the fruit of Momordica grosvenori on epstein-barr virus early antigen induced by tumor promoter 12-O-tetradecanoylphorbol-13-acetate. J Agric Food Chem . 2002;50:6710-6715.
12. Takasaki M, Konoshima T, Murata Y, et al. Anticarcinogenic activity of natural sweeteners, cucurbitane glycosides, from Momordica grosvenori. Cancer Lett. 2003;198:37-42.
13. Konoshima T, Takasaki M. Cancer-chemopreventive effects of natural sweeteners and related compounds. Pure Appl Chem. 2002;74:1309-1316.
14. Ling Yeouruenn, A New Compendium of Materia Medica, 1995 Science Press, Beijing.
15. Dawson GE, et al., Process and composition for sweet juice from Cucurbitaceae fruit, U.S. patent 5,411,755, May 2, 1995.
16. Blumert M and Liu Jialiu, Jiaogulan: China's Immortality Herb, 1999 Torchlight Pub., Badger, CA.
17. Dai Yinfang and Liu Chengjun, Fruit as Medicine, 1986 The Ram's Skull Press, Kuranda, Australia.
18. Dragon River Health Products, http://www.dragonriver.net/eng/home.html
19. Kinghorn AD and Soejarto DD, Discovery of terpenoid and phenolic sweeteners from plants, Pure Applied Chemistry 2002; 74(7): 1169-1179.
20. Guangxi Science and Technology Information Network, http://www.gxsti.net.cn/esti/2resourse.htm
21. People's Daily Online, Culture: Guilin has more centenarians, November 26, 1999; http://fpeng.peopledaily.com.cn/199911/26/eng19991126R107.html
22. Strait's Times, Village of longevity gets onto tourist map, http://straitstimes.asia1.com.sg/mnt/html/webspecial/gallery/livelong/story.html
23. Hsu HY, et al., Oriental Materia Medica, 1986 Oriental Healing Arts Institute, Long Beach, CA
24. Croom, EM Jr., Luo Han Guo: A literature review, http://www.hort.purdue.edu/newcrop/articles/momordica%20croom.html
25. Lee CH., Intense sweetener from Lo Han Kuo, Experientia 1975, 31(5): 533-534.
26. Shi H, et al., Antioxidant property of fructus momordicae extract, 1996 Biochemistry and Molecular Biology International 1996; 40 (6): 1111-1121.
27. Konoshima T and Takasaki M, Cancer-chemopreventive effects of natural sweeteners and related compounds, Pure Applied Chemistry 2002; 74(7): 1309-1316.
28. Katiyar SK and Mukhtar H, Tea antioxidants in cancer chemoprevention, Journal of Cellular Biochemistry, Supplement 1997; 27: 59-67.
29. http://www.itmonline.org/arts/luohanguo.htm
30. S. Takagi, et. al., "Anti-Allergic Activity of Glycopeptide Isolated from Perilla Frutescens," Journal of Traditional Medicines, 18 no.6 (2001): 239-244.
31. Xiang-Yang Qi, Wei-Jun Chen, Li-Qin Zhang, Bi-Jun Xie, "Mogrosides Extract From Siraitia Grosvenori Scavenges Free Radicals in Vitro and Lowers Oxidative Stress, Serum Glucose, and Lipid Levels in Alloxan-Induced Diabetic Mice," Nutrition Research, 4 no. 28 (April 2008):278-284.
32. Yasushi A. Suzuki, et. al., "Antidiabetic Effect of Long-Term Supplementation with Siraitia Grosvenori on the Spontaneously Diabetic Goto Kakizaki Rat," British Journal of Nutrition, 97 (2007): 770 - 775.
33. Xiang-Yang Qi, Wei-Jun Chen, Li-Qin Zhang, Bi-Jun Xie, "Effect of a Siraitia Grosvenori Extract Containing Mogrosides on the Cellular Immune System of Type 1 Diabetes Mellitus Mice," Molecular Nutrition and Food Research, 50 no. 8 (August 2006): 732-738.
34. Makapugay HC, Nanayakkara NP, Soejarto DD, Kinghorn AD. High-performance liquid chromatographic analysis of the major sweet principle of lo han kuo fruits. J Agric Food Chem. 1985;33:348-350.

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